Results 21 to 30 of about 283,436 (252)
Single molecule thermodynamics of ATP synthesis by F1-ATPase
New Journal of Physics, 2015 F _o F _1 -ATP synthase is a factory for synthesizing ATP in virtually all cells. Its core machinery is the subcomplex F _1 -motor (F _1 -ATPase) and performs the reversible mechanochemical coupling.
Shoichi Toyabe, Eiro Muneyuki
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Connecting two arrays: The emerging role of actin-microtubule cross-linking motor proteins
Frontiers in Plant Science, 2015 The cytoskeleton of plant cells, consisting of actin filaments (AFs) and microtubules (MTs), is a central structure for various intracellular processes, such as cell division, isotropic and polar growth, vesicle transport, cell shape and morphogenesis ...
René eSchneider, Staffan ePersson
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Cortical proteins may provide motor resilience in older adults
Scientific Reports, 2021 Motor resilience proteins may be a high value therapeutic target that offset the negative effects of pathologies on motor function. This study sought to identify cortical proteins associated with motor decline unexplained by brain pathologies that ...
Aron S. Buchman +11 more
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Frontiers in Cellular Neuroscience, 2015 Reports from neural cell cultures and experimental animal studies provide evidence of age- and disease-related changes in retrograde transport of spent or misfolded proteins destined for degradation or recycling. However, few studies address these issues
Orwa eAboud +5 more
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Symmetry Breaking and Emergence of Directional Flows in Minimal Actomyosin Cortices
Cells, 2020 Cortical actomyosin flows, among other mechanisms, scale up spontaneous symmetry breaking and thus play pivotal roles in cell differentiation, division, and motility.
Sven K. Vogel +5 more
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Myosin-V Induces Cargo Immobilization and Clustering at the Axon Initial Segment
Frontiers in Cellular Neuroscience, 2017 The selective transport of different cargoes into axons and dendrites underlies the polarized organization of the neuron. Although it has become clear that the combined activity of different motors determines the destination and selectivity of transport,
Anne F. J. Janssen +5 more
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Nonlinearity of mechanochemical motions in motor proteins. [PDF]
PLoS Computational Biology, 2010 The assumption of linear response of protein molecules to thermal noise or structural perturbations, such as ligand binding or detachment, is broadly used in the studies of protein dynamics.
Yuichi Togashi +2 more
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Dendritic trafficking faces physiologically critical speed-precision tradeoffs
eLife, 2016 Nervous system function requires intracellular transport of channels, receptors, mRNAs, and other cargo throughout complex neuronal morphologies. Local signals such as synaptic input can regulate cargo trafficking, motivating the leading conceptual model
Alex H Williams +3 more
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eLife, 2017 The localisation of oskar mRNA to the posterior of the Drosophila oocyte defines where the abdomen and germ cells form in the embryo. Kinesin 1 transports oskar mRNA to the oocyte posterior along a polarised microtubule cytoskeleton that grows from non ...
Ross Nieuwburg +6 more
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Motor Proteins: Myosin Mechanosensors [PDF]
Current Biology, 2008 Mechanosensation is emerging as a general principle of myosin motors. As demonstrated in a recent study, the single-headed myosin I molecule is an exquisite mechanosensor, able to sense strain over a very small force range.
Kee, Yee-Seir, Robinson, Douglas N.
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