Results 31 to 40 of about 8,367,716 (316)
Mechanisms of Regulation in Intraflagellar Transport
Cells, 2022 Cilia are eukaryotic organelles essential for movement, signaling or sensing. Primary cilia act as antennae to sense a cell’s environment and are involved in a wide range of signaling pathways essential for development. Motile cilia drive cell locomotion
Wouter Mul +2 more
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Myosin repertoire expansion coincides with eukaryotic diversification in the Mesoproterozoic era
BMC Evolutionary Biology, 2017 Background The last eukaryotic common ancestor already had an amazingly complex cell possessing genomic and cellular features such as spliceosomal introns, mitochondria, cilia-dependent motility, and a cytoskeleton together with several intracellular ...
Martin Kollmar, Stefanie Mühlhausen
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Coupling of Two Motor Proteins: a New Motor Can Move Faster [PDF]
, 2005 We study the effect of a coupling between two motor domains in highly-processive motor protein complexes. A simple stochastic discrete model, in which the two parts of the protein molecule interact through some energy potential, is presented.
Anatoly B. Kolomeisky +8 more
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The agrin gene codes for a family of basal lamina proteins that differ in function and distribution [PDF]
, 1992 We isolated two cDNAs that encode isoforms of agrin, the basal lamina protein that mediates the motor neuron-induced aggregation of acetylcholine receptors on muscle fibers at the neuromuscular junction.
Escher, G. +6 more
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Cortical proteins may provide motor resilience in older adults
Scientific Reports, 2021 Motor resilience proteins may be a high value therapeutic target that offset the negative effects of pathologies on motor function. This study sought to identify cortical proteins associated with motor decline unexplained by brain pathologies that ...
Aron S. Buchman +11 more
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Modelling Molecular Motors as Folding-Unfolding Cycles [PDF]
, 1999 We propose a model for motor proteins based on a hierarchical Hamiltonian that we have previously introduced to describe protein folding. The proposed motor model has high efficiency and is consistent with a linear load-velocity response.
+8 more
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The landscape of human mutually exclusive splicing
Molecular Systems Biology, 2017 Mutually exclusive splicing of exons is a mechanism of functional gene and protein diversification with pivotal roles in organismal development and diseases such as Timothy syndrome, cardiomyopathy and cancer in humans.
Klas Hatje +10 more
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Single molecule thermodynamics of ATP synthesis by F1-ATPase
New Journal of Physics, 2015 F _o F _1 -ATP synthase is a factory for synthesizing ATP in virtually all cells. Its core machinery is the subcomplex F _1 -motor (F _1 -ATPase) and performs the reversible mechanochemical coupling.
Shoichi Toyabe, Eiro Muneyuki
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Frontiers in Cellular Neuroscience, 2015 Reports from neural cell cultures and experimental animal studies provide evidence of age- and disease-related changes in retrograde transport of spent or misfolded proteins destined for degradation or recycling. However, few studies address these issues
Orwa eAboud +5 more
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Symmetry Breaking and Emergence of Directional Flows in Minimal Actomyosin Cortices
Cells, 2020 Cortical actomyosin flows, among other mechanisms, scale up spontaneous symmetry breaking and thus play pivotal roles in cell differentiation, division, and motility.
Sven K. Vogel +5 more
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