Results 111 to 120 of about 8,367,716 (316)
Phenomenological analysis of ATP dependence of motor proteins.
PLoS ONE, 2012 In this study, through phenomenological comparison of the velocity-force data of processive motor proteins, including conventional kinesin, cytoplasmic dynein and myosin V, I found that, the ratio between motor velocities of two different ATP ...
Yunxin Zhang
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Realistic Models of Biological Motion
, 1998 The origin of biological motion can be traced back to the function of molecular motor proteins. Cytoplasmic dynein and kinesin transport organelles within our cells moving along a polymeric filament, the microtubule.
Ajdari +42 more
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Role of cytoskeletal motor proteins in viral infection.
Postępy Higieny i Medycyny Doświadczalnej, 2012 Cytoskeleton, composed of actin filaments, microtubules and intermediate filaments, regulates many processes in the cell, e.g. intracellular transport. Actin and microtubules are polarized structures, along which bidirectional transport of motor proteins
A. Słońska +3 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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Cell Reports, 2016 Long-distance intracellular transport of organelles, mRNA, and proteins (“cargo”) occurs along the microtubule cytoskeleton by the action of kinesin and dynein motor proteins, but the vast network of factors involved in regulating intracellular cargo ...
Amber L. Jolly +13 more
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Journal of Biological Chemistry, 2012 Background: The flagellar motor generates bidirectional rotation using the proteins FliG, FliM, and CheY and membrane-bound stator complexes. Results: The structures of portions of FliG and FliM in complex allow for insights into switching and structure.
A. S. Vartanian +4 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Cytoplasmic microtubule sliding
Communicative & Integrative Biology, 2010 There are well known examples in nature of microtubules dramatically changing their function by re-organizing their structure. Most interphase animal cells rely on the radial organization of the microtubule network for precise cargo delivery.
Amber L. Jolly, Vladimir I. Gelfand
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Transport of organelles by elastically coupled motor proteins
, 2016 Motor-driven cargo transport is a complex phenomenon where multiple motor proteins attached on to a cargo engage in pulling activity, often leading to tug-of-war, displaying bidirectional motion. However, most mathematical and computational models ignore
Bhat, Deepak, Gopalakrishnan, Manoj
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Motor proteins: A dynamic duo [PDF]
Current Biology, 1996 The interactions between the microtubule motor cytoplasmic dynein and its putative regulator dynactin have been shown to be dynamic and complex.
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