Results 101 to 110 of about 830,352 (306)

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Sensor-Based Quantification of MDS-UPDRS III Subitems in Parkinson’s Disease Using Machine Learning

Sensors
Wearable sensors could be beneficial for the continuous quantification of upper limb motor symptoms in people with Parkinson’s disease (PD). This work evaluates the use of two inertial measurement units combined with supervised machine learning models to
Rene Peter Bremm, Lukas Pavelka, Maria Moscardo Garcia, Laurent Mombaerts, Rejko Krüger, Frank Hertel   +5 more
doaj   +1 more source

Automated operant assessments of Huntington's Disease mouse models [PDF]

, 2018
Huntington’s disease (HD) presents clinically with a triad of motor, cognitive, and psychiatric symptoms. Cognitive symptoms often occur early within the disease progression, prior to the onset of motor symptoms, and they are significantly burdensome to ...
A Burns, A Lunkes, AD Lawrence, AD Lawrence, AE Horner, AJ Mitchell, AJ Morton, B Baldo, B Skinner, C Clelland, C Kipps, CF Jacobsen, CL Julien, D Craufurd, D Helder, D Yang, DC Rogers, E Dowd, E Dowd, E Mayer, E Yhnell, E Yhnell, E Yhnell, F Yue, J Paulsen, J Snowden, J Talpos, J-C Bensadoun, JC Jacobsen, JC Thompson, JF Gusella, JM Raamsdonk Van, JN Crawley, JR Slaughter, JS Paulsen, K Kubota, L Mangiarini, L Menalled, M Carli, M Carli, M D’amato, MD Döbrössy, MD Döbrössy, ME MacDonald, P Thompson, PC Curtin, PJ Brasted, PW Faber, R Diamond, RC Josiassen, RC Trueman, RC Trueman, RC Trueman, RC Trueman, RC Trueman, RE Ready, S Baudic, S Brooks, S Brooks, S Hörsten von, S Kirkwood, S Klöppel, S-H Yang, SA Johnson, SB Dunnett, SB Dunnett, SB Dunnett, SB Dunnett, SB Dunnett, SJ Tabrizi, SJ Tabrizi, SJ Tabrizi, SM McTighe, SP Brooks, SP Brooks, SP Brooks, T Humby, T Robbins, T-B Robins Wahlin, V Tucci, W Duan, WD Spaulding   +81 more
core   +2 more sources

Relationship between the type and side of motor symptoms with the prevalence of non-motor symptoms in Parkinson's disease

Neurología (English Edition), 2011
the relationship between laterality and asymmetry of Parkinson's disease and non-motor dysfunction has been studied mainly from the perspective of cognitive functions, and the few studies that have included other symptoms have mixed reports. The relationship between non-motor symptoms and the type of onset of the disease has not been studied in detail ...
M. Rodríguez-Violante, A. Cervantes-Arriaga, A. Villar-Velarde, T. Corona   +3 more
openaire   +3 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Gender discrepancies and differences in motor and non-motor symptoms, cognition, and psychological outcomes in the treatment of Parkinson’s disease with subthalamic deep brain stimulation

Frontiers in Neurology
Available data suggest that there may be gender differences in the effect of STN-DBS in the treatment of Parkinson’s disease (PD). The aim of this study was to review data on gender discrepancies and gender differences in clinical outcomes in PD patients
Martijn Hendriks, Martijn Hendriks, Ruben Saman Vinke, Dejan Georgiev, Dejan Georgiev   +4 more
doaj   +1 more source

Eye movement desensitisation and reprocessing (EMDR) treatment associated with parent management training (PMT) for the acute symptoms in a patient with PANDAS syndrome: a case report [PDF]

, 2019
BACKGROUND: The purpose of this report was to present the results of eye movement desensitisation and reprocessing (EMDR) therapy associated with parent management training (PMT) in a child with paediatric autoimmune neuropsychiatric disorder associated ...
Duse, M., Guido, C. A., Spalice, A., Zicari, A. M.   +3 more
core   +1 more source

MOTOR RETARDATION AS A MANIC-DEPRESSIVE SYMPTOM [PDF]

American Journal of Psychiatry, 1909
n ...
openaire   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source