Results 31 to 40 of about 38,779 (193)
JID Innovations, 2023 Cutaneous squamous cell carcinoma (cSCC) is the second most common cancer, with increased incidence in immunosuppressed patients. β-Human papillomavirus has been proposed as a contributor to cSCC risk partly on the basis of increased β-human ...
Luke H. Johnson +5 more
doaj +1 more source
Cryo EM Analysis Reveals Inherent Flexibility of Authentic Murine Papillomavirus Capsids
Viruses, 2021 Human papillomavirus (HPV) is a significant health burden and leading cause of virus-induced cancers. However, studies have been hampered due to restricted tropism that makes production and purification of high titer virus problematic.
Samantha R. Hartmann +6 more
doaj +1 more source
Viruses, 2022 Murine papillomavirus, MmuPV1, causes natural infections in laboratory mice that can progress to squamous cell carcinoma (SCC) making it a useful preclinical model to study the role of papillomaviruses in cancer.
Ruben Moreno +2 more
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A novel lineage-tracing mouse model for studying early MmuPV1 infections
eLife, 2022 Human papillomaviruses are DNA viruses that ubiquitously infect humans and have been associated with hyperproliferative lesions. The recently discovered mouse specific papillomavirus (MmuPV1) provides the opportunity to study papillomavirus infections in
Vural Yilmaz +4 more
doaj +1 more source
Induction of autoantibodies to mouse CCR5 with recombinant papillomavirus particles [PDF]
Proceedings of the National Academy of Sciences, 1999 The vertebrate immune system has evolved to respond vigorously to microbial infection but to ignore self-antigens. Evidence has emerged that B cell responses to viruses are initiated by immune recognition of ordered arrays of antigen on the viral surface.
B, Chackerian, D R, Lowy, J T, Schiller
openaire +2 more sources
An Infection-Based Murine Model for Papillomavirus-Associated Head and Neck Cancer
mBio, 2020 Human papillomavirus (HPV) is the most common sexually transmitted pathogen, and high-risk HPVs contribute to 5% of human cancers, including 25% of head and neck squamous cell carcinomas (HNSCCs).
Tao Wei +3 more
doaj +1 more source
A novel pre-clinical murine model to study the life cycle and progression of cervical and anal papillomavirus infections. [PDF]
PLoS ONE, 2015 Papillomavirus disease and associated cancers remain a significant health burden in much of the world. The current protective vaccines, Gardasil and Cervarix, are expensive and not readily available to the underprivileged.
Nancy M Cladel +5 more
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Life cycle heterogeneity in animal models of human papillomavirus-associated disease [PDF]
, 2002 Animal papillomaviruses are widely used as models to study papillomavirus infection in humans despite differences in genome organization and tissue tropism. Here, we have investigated the extent to which animal models of papillomavirus infection resemble
Peh, W.L. +21 more
core +2 more sources
Sex-dependent development of Kras-induced anal squamous cell carcinoma in mice.
PLoS ONE, 2021 Anal squamous cell carcinoma (SCC) will be diagnosed in an estimated 9,080 adults in the United States this year, and rates have been rising over the last several decades.
Morgan T Walcheck +7 more
doaj +2 more sources
Isolation of three novel rat and mouse papillomaviruses and their genomic characterization. [PDF]
, 2012 Despite a growing knowledge about the biological diversity of papillomaviruses (PV), only little is known about non-human PV in general and about PV mice models in particular.
Ingo Nindl (126623) +23 more
core +1 more source