Results 41 to 50 of about 38,779 (193)

MmuPV1 E7's interaction with PTPN14 delays Epithelial differentiation and contributes to virus-induced skin disease.

PLoS Pathogens, 2023
Human papillomaviruses (HPVs) contribute to approximately 5% of all human cancers. Species-specific barriers limit the ability to study HPV pathogenesis in animal models.
James C Romero-Masters, Miranda Grace, Denis Lee, Joshua Lei, Melanie DePamphilis, Darya Buehler, Rong Hu, Ella Ward-Shaw, Simon Blaine-Sauer, Nathalie Lavoie, Elizabeth A White, Karl Munger, Paul F Lambert   +12 more
doaj   +3 more sources

Papillomavirus E5: the smallest oncoprotein with many functions [PDF]

, 2011
Papillomaviruses (PVs) are established agents of human and animal cancers. They infect cutaneous and mucous epithelia. High Risk (HR) Human PVs (HPVs) are consistently associated with cancer of the uterine cervix, but are also involved in the ...
Roperto, S., Borzacchiello, G., Venuti Aldo, Sante Roperto, Corteggio, A., BORZACCHIELLO, GIUSEPPE, Giuseppe Borzacchiello, Roperto Sante, CORTEGGIO, ANNUNZIATA, Francesca Paolini, Nasir, L., A. Venuti, Paolini Francesca, Aldo Venuti, Paolini, F., L. Nasir, Lubna Nasir, Annunziata Corteggio, Corteggio Annunziata, F. Paolini, Borzacchiello Giuseppe, ROPERTO, SANTE, M.S. Campo, Maria S Campo, Nasir Lubna, Venuti, A., Campo, M.S., Campo Maria S   +27 more
core   +1 more source

Increased Growth of a Newly Established Mouse Epithelial Cell Line Transformed with HPV-16 E7 in Diabetic Mice. [PDF]

PLoS ONE, 2016
Epidemiological evidence supports that infection with high-risk types of human papillomavirus (HPV) can interact with host and environmental risk factors to contribute to the development of cervical, oropharyngeal, and other anogenital cancers.
Lan He, Priscilla T Y Law, Siaw Shi Boon, Chuqing Zhang, Wendy C S Ho, Lawrence Banks, C K Wong, Juliana C N Chan, Paul K S Chan   +8 more
doaj   +1 more source

CCCTC-binding factor recruitment to the early region of the human papillomavirus type 18 genome regulates viral oncogene expression [PDF]

, 2015
C.P. was supported by a Ph.D. studentshipfunded by the University of St. Andrews, School of Medicine. I.P. is supported by a Cancer Research UK (CRUK) Ph.D. studentship awarded to J.L.P. and S.R. I.G. and N.C.
Coleman, Nicholas, Roberts, David, Groves, Ian, Powis, Simon J, Roberts, Sally, Roberts, David C, Pentland, Ieisha, Parish, Joanna; id_orcid, Parish, Joanna L, Paris, Christian   +9 more
core   +2 more sources

Down-regulation of MHC class I is a property common to papillomavirus E5 proteins [PDF]

, 2006
The E5 protein family of papillomaviruses comprises small hydrophobic proteins which are associated with the cell endomembrane compartments. The functions of the E5 proteins, particularly those of HPV, are still far from clear.
Fife, K.H., G.H. Ashrafi, Ashrafi, G, Campo, M, D.R. Brown, Ashrafi, G.H., M.S. Campo, Brown, D.R., Fife, K, Campo, M.S., Brown, D R, K.H. Fife   +11 more
core   +1 more source

HPV-positive murine oral squamous cell carcinoma: development and characterization of a new mouse tumor model for immunological studies

Journal of Translational Medicine, 2023
Background Infection with high-risk human papillomavirus (HPV) strains is one of the risk factors for the development of oral squamous cell carcinoma (OSCC).
Ziva Modic, Maja Cemazar, Bostjan Markelc, Andrej Cör, Gregor Sersa, Simona Kranjc Brezar, Tanja Jesenko   +6 more
doaj   +1 more source

Immunization and immunotherapy for cancers involving infection by a human papillomavirus in a mouse model [PDF]

Proceedings of the National Academy of Sciences, 2002
We describe a protocol for generating a potent cellular immune response against viral-infected cells, and demonstrate its efficacy and safety in a mouse model of human cancer associated with infection by a human papillomavirus (HPV). In the mouse model, the mouse tumor TC-1, which expresses the E7 oncoprotein from HPV-16, is used as a surrogate for ...
Jin, Li, Ying, Sun, Alan, Garen
openaire   +2 more sources

Downregulation of major histocompatibility complex class I in bovine papillomas [PDF]

, 2004
Bovine papillomavirus (BPV) induces papillomas in cattle; in the great majority of cases, these regress due to the host immune response, but they can persist and progress to malignancy.
Marchetti, B, Araibi, E.H., Ashrafi, G.H., Campo, M.S., Marchetti, B., Araibi, E. H.   +5 more
core   +1 more source

Hierarchy of polyadenylation site usage by bovine papillomavirus in transformed mouse cells [PDF]

Journal of Virology, 1993
The great majority of viral mRNAs in mouse C127 cells transformed by bovine papillomavirus type 1 (BPV) have a common 3' end at the early polyadenylation site which is 23 nucleotides (nt) downstream of a canonical poly(A) consensus signal. Twenty percent of BPV mRNA from productively infected cells bypasses the early polyadenylation site and uses the ...
E M, Andrews, D, DiMaio
openaire   +2 more sources

Human papillomavirus 16 L2 inhibits the transcriptional activation function, but not the DNA replication function, of HPV-16 E2 [PDF]

, 2005
In this study we analysed the outcome of the interaction between HPV-16 L2 and E2 on the transactivation and DNA replication functions of E2. When E2 was expressed on its own, it transactivated a number of E2-responsive promoters but co-expression of L2 ...
Morgan, I.M., Cordano, P., Taylor, E.R., Everett, R., R. Everett, A. Okoye, M.S. Campo, P. Cordano, E.R. Taylor, Campo, M.S., I.M. Morgan, Okoye, A.   +11 more
core   +1 more source