Results 51 to 60 of about 887,744 (175)

Key aspects of papillomavirus infection influence the host cervicovaginal microbiome in a preclinical murine papillomavirus (MmuPV1) infection model

mBio
Human papillomaviruses (HPVs) are the most common sexually transmitted infection in the United States and are a major etiological agent of cancers in the anogenital tract and oral cavity.
Megan E. Spurgeon, Elizabeth C. Townsend, Simon Blaine-Sauer, Stephanie M. McGregor, Mark Horswill, Johan A. den Boon, Paul Ahlquist, Lindsay Kalan, Paul F. Lambert   +8 more
doaj   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Human papillomavirus 16 L2 inhibits the transcriptional activation function, but not the DNA replication function, of HPV-16 E2 [PDF]

, 2005
In this study we analysed the outcome of the interaction between HPV-16 L2 and E2 on the transactivation and DNA replication functions of E2. When E2 was expressed on its own, it transactivated a number of E2-responsive promoters but co-expression of L2 ...
Morgan, I.M., Cordano, P., Taylor, E.R., Everett, R., R. Everett, A. Okoye, M.S. Campo, P. Cordano, E.R. Taylor, Campo, M.S., I.M. Morgan, Okoye, A.   +11 more
core   +1 more source

The rabbit as an animal model to study innate immunity genes: Is it better than mice?

Frontiers in Immunology, 2022
The European rabbit (Oryctolagus cuniculus) was the first animal model used to understand human diseases like rabies and syphilis. Nowadays, the rabbit is still used to study several human infectious diseases like syphilis, HIV and papillomavirus ...
João Soares, João Soares, Ana Pinheiro, Ana Pinheiro, Pedro José Esteves, Pedro José Esteves, Pedro José Esteves, Pedro José Esteves   +7 more
doaj   +1 more source

Equine sarcoids: Bovine Papillomavirus type 1 transformed fibroblasts are sensitive to cisplatin and UVB induced apoptosis and show aberrant expression of p53 [PDF]

, 2012
Bovine papillomavirus type 1 infects not only cattle but also equids and is a causative factor in the pathogenesis of commonly occurring equine sarcoid tumours.
Finlay, M., Morgan Iain M, M Campo, Margaret Finlay, Campo M, Finlay Margaret, Yuan ZhengQiang, Lubna Nasir, Morgan, I.M., Campo, M., ZhengQiang Yuan, Iain M Morgan, Nasir Lubna, Yuan, Z., Nasir, L.   +14 more
core   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

E5 protein of human papillomavirus 16 downregulates HLA class I and interacts with the heavy chain via its first hydrophobic domai [PDF]

, 2006
Human papillomavirus type 16 E5 protein (HPV-16 E5) is expressed early in papillomavirus infection and is localised primarily in the cell Golgi apparatus (GA) and endoplasmic reticulum. E5 prevents transport of the major histocompatibility class I (MHC I;
Marchetti, Barbara, Ashrafi, G. Hossein, Haghshenas, Mohammad, Ashrafi, G.H., Haghshenas, M., Campo, M.S., Marchetti, B., Campo, M. Saveria   +7 more
core   +1 more source

Design and Immunological Validation of Macaca fascicularis Papillomavirus Type 3 Based Vaccine Candidates in Outbred Mice: Basis for Future Testing of a Therapeutic Papillomavirus Vaccine in NHPs

Frontiers in Immunology, 2021
Persistent human papillomavirus (HPV) infections are causative for cervical neoplasia and carcinomas. Despite the availability of prophylactic vaccines, morbidity and mortality induced by HPV are still too high.
Patrick Neckermann, Ditte Rahbaek Boilesen, Ditte Rahbaek Boilesen, Torsten Willert, Cordula Pertl, Silke Schrödel, Christian Thirion, Benedikt Asbach, Peter Johannes Holst, Peter Johannes Holst, Ralf Wagner, Ralf Wagner   +11 more
doaj   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Downregulation of major histocompatibility complex class I in bovine papillomas [PDF]

, 2004
Bovine papillomavirus (BPV) induces papillomas in cattle; in the great majority of cases, these regress due to the host immune response, but they can persist and progress to malignancy.
Marchetti, B, Araibi, E.H., Ashrafi, G.H., Campo, M.S., Marchetti, B., Araibi, E. H., E. H. Araibi   +6 more
core   +1 more source