Results 111 to 120 of about 485,078 (155)

Structural Insight into Molecular Inhibitory Mechanism of InsP₆ on African Swine Fever Virus mRNA-Decapping Enzyme g5Rp. [PDF]

J Virol, 2022
Yang Y, Zhang C, Li X, Li L, Chen Y, Yang X, Zhao Y, Chen C, Wang W, Zhong Z, Yang C, Huang Z, Su D.   +12 more
europepmc   +1 more source

Conformational control of eukaryotic mRNA decapping by Dcp2 [PDF]

, 2011
The lifetime of eukaryotic messenger RNA is highly regulated by elements on both the 5' and 3' ends of the message. Methylated guanine "cap" on the 5' end of a message is critical for nuclear export, protein translation, and stability of a message.
Floor, Stephen N.
core  

Creatine mitigates neurogenesis impairment caused by defective DcpS decapping

Scientific Reports
Biallelic mutations in the DCPS gene disrupting the decapping activity of the scavenger decapping protein DcpS, leads to neurodevelopmental deficiencies and intellectual disability.
Jun Yang, Geeta Palsule, Xinfu Jiao, Jaime S. Messenger, Ronald P. Hart, Megerditch Kiledjian   +5 more
doaj   +1 more source

miR-4293 upregulates lncRNA WFDC21P by suppressing mRNA-decapping enzyme 2 to promote lung carcinoma proliferation. [PDF]

Cell Death Dis, 2021
Zhang Q, Yan YF, Lv Q, Li YJ, Wang RR, Sun GB, Pan L, Hu JX, Xie N, Zhang C, Tian BC, Jiao F, Xu S, Wang PY, Xie SY.   +14 more
europepmc   +1 more source

N4BP1 uses tandem KH domains to associate with EDC4 and mRNA decapping factors in P-bodies. [PDF]

Commun Biol
Piłat P, Garg A, Heinemann U, Wilamowski M, Jura J.   +4 more
europepmc   +1 more source

InsP₇ is a small-molecule regulator of NUDT3-mediated mRNA decapping and processing-body dynamics. [PDF]

Proc Natl Acad Sci U S A, 2020
Sahu S, Wang Z, Jiao X, Gu C, Jork N, Wittwer C, Li X, Hostachy S, Fiedler D, Wang H, Jessen HJ, Kiledjian M, Shears SB.   +12 more
europepmc   +1 more source

The trypanosome mRNA decapping enzyme ALPH1 prefers caps without m7G methylation and produces diphosphate RNA. [PDF]

Nucleic Acids Res
Pereira L, Dzadz DA, Londoño PAC, Warminski M, Kowalska J, Seifert N, Braune S, Holetz F, Zoltner M, Kramer S, Górna MW.   +10 more
europepmc   +1 more source

mRNA decapping enzyme2 DCP2 expression correlates with progression and prognosis of hepatocellular carcinoma. [PDF]

Sci Rep
Huang T, Wang R, Lu C, Zhang J.
europepmc   +1 more source

A protein-proximity screen reveals Ebola virus co-opts the mRNA decapping complex through the scaffold protein EDC4. [PDF]

Nat Commun
Donahue CJ, Kesari AS, Thakur N, Wang L, Stubbs SH, Williams CG, Sharma SB, Kirby CD, Leung DW, Aryal UK, Basler CF, LaCount DJ, Davey RA.   +12 more
europepmc   +1 more source

Molecular basis of the selective processing of short mRNA substrates by the DcpS mRNA decapping enzyme. [PDF]

Proc Natl Acad Sci U S A, 2020
Fuchs AL, Wurm JP, Neu A, Sprangers R.
europepmc   +1 more source