Results 21 to 30 of about 1,406,247 (286)

In vivo Imaging of oskar mRNA transport reveals the mechanism of posterior localization [PDF]

open access: yes, 2008
oskar mRNA localization to the posterior of the Drosophila oocyte defines where the abdomen and germ cells form in the embryo. Although this localization requires microtubules and the plus end-directed motor, kinesin, its mechanism is controversial and ...
Zimyanin, Vitaly L   +16 more
core   +1 more source

A cytoplasmic complex mediates specific mRNA recognition and localization in yeast [PDF]

open access: yes, 2011
In eukaryotes, hundreds of mRNAs are localized by specialized transport complexes. For localization, transcripts are recognized by RNA-binding proteins and incorporated into motor-containing messenger ribonucleoprotein particles (mRNPs).
Henning Urlaub   +41 more
core   +2 more sources

mRNA Localization Revisited [PDF]

open access: yesCell, 2001
Book ...
Kiebler, Michael, Macchi, Paolo
openaire   +3 more sources

Controlling mRNA localization with light [PDF]

open access: yesNature Methods, 2020
An optogenetic approach allows researchers to probe how mRNA localization affects cellular processes.
openaire   +2 more sources

Mechanisms of Subcellular mRNA Localization [PDF]

open access: yesCell, 2002
Localization of RNA is a widespread and efficient way to target gene products to a specific region of a cell or embryo. This strategy of posttranscriptional gene regulation utilizes a variety of distinct mechanisms to regulate the movement and anchoring of different transcripts.
Kloc, Malgorzata   +2 more
openaire   +2 more sources

Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation in vertebrates

open access: yeseLife, 2018
As microtubule-organizing centers of animal cells, centrosomes guide the formation of the bipolar spindle that segregates chromosomes during mitosis.
Guadalupe Sepulveda   +11 more
doaj   +1 more source

Opposing roles for Egalitarian and Staufen in transport, anchoring and localization of oskar mRNA in the Drosophila oocyte.

open access: yesPLoS Genetics, 2021
Localization of oskar mRNA includes two distinct phases: transport from nurse cells to the oocyte, a process typically accompanied by cortical anchoring in the oocyte, followed by posterior localization within the oocyte.
Sabine Mohr   +6 more
doaj   +1 more source

Appearance of phloridzin-sensitive glucose transport is not controlled at mRNA level in rabbit jejunal enterocytes [PDF]

open access: yes, 1992
Glucose uptake by rabbit intestine has been shown to be confined to the upper two-thirds of jejunal villi. Inhibition by phloridzin shows most of this transport to take place through the Na(+)-glucose linked transporter (SGLT1).
Turvey, A   +5 more
core   +1 more source

Split-BioID a conditional proteomics approach to monitor the composition of spatiotemporally defined protein complexes

open access: yesNature Communications, 2017
The BioID approaches takes advantage of the promiscuous biotinylation enzyme (BirA*) to identify proteins that closely interact. Here the authors improve the resolution of BioID using a protein fragment complementation approach that allows the assignment
Isabel Myriam Schopp   +6 more
doaj   +1 more source

Quantification of pre-mRNA escape rate and synergy in splicing [PDF]

open access: yes, 2014
Splicing reactions generally combine high speed with accuracy. However, some of the pre-mRNAs escape the nucleus with a retained intron. Intron retention can control gene expression and increase proteome diversity.
Becskei, Attila   +13 more
core   +1 more source

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