Results 31 to 40 of about 3,806,370 (293)
Regulation of SUMOylation on RNA metabolism in cancers
Frontiers in Molecular Biosciences, 2023 Post-translational modifications of proteins play very important roles in regulating RNA metabolism and affect many biological pathways. Here we mainly summarize the crucial functions of small ubiquitin-like modifier (SUMO) modification in RNA metabolism
Yingting Cao +3 more
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Processing and degradation of chloroplast mRNA
Biochimie, 2000 The conversion of genetic information stored in DNA into a protein product proceeds through the obligatory intermediate of messenger RNA. The steady-state level of an mRNA is determined by its relative synthesis and degradation rates, i.e., an interplay between transcriptional regulation and control of RNA stability.
R A, Monde, G, Schuster, D B, Stern
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Interplay between exonic splicing enhancers, mRNA processing, and mRNA surveillance in the dystrophic Mdx mouse. [PDF]
PLoS ONE, 2007 Pre-mRNA splicing, the removal of introns from RNA, takes place within the spliceosome, a macromolecular complex composed of five small nuclear RNAs and a large number of associated proteins. Spliceosome assembly is modulated by the 5' and 3' splice site
Massimo Buvoli +2 more
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Genome Biology, 2018 Background The multifaceted control of gene expression requires tight coordination of regulatory mechanisms at transcriptional and post-transcriptional level.
Seyed Yahya Anvar +11 more
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Modulation of mRNA 3′-End Processing and Transcription Termination in Virus-Infected Cells
Frontiers in Immunology, 2022 Eukaryotic mRNA 3´-end processing is a multi-step process beginning with pre-mRNA transcript cleavage followed by poly(A) tail addition. Closely coupled to transcription termination, 3´-end processing is a critical step in the regulation of gene ...
Aarthi Vijayakumar +2 more
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Regulation of pre-mRNA processing by src [PDF]
Current Biology, 1995 Changes in gene expression in response to external signals provide a key mechanisms for the regulation of higher eukaryotic cell functions. The importance of transcriptional control in the response of cells to growth factors and cytokines has been extensively documented, but gene expression has also been shown to be controlled at other levels, such as ...
Neel, Henry +3 more
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Biochemical characterization and three-dimensional structure analysis of the yeast cleavage and polyadenylation factor CPF [PDF]
, 2008 In eukaryotes, protein-encoding genes are transcribed in the nucleus by RNA polymerase II (RNAP II). Before the gene transcript (pre-mRNA) is transported to the cytoplasm and can function in translation, it has to undergo three specific maturation ...
Paguet, Bertrand
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Context-dependent deposition and regulation of mRNAs in P-bodies
eLife, 2018 Cells respond to stress by remodeling their transcriptome through transcription and degradation. Xrn1p-dependent degradation in P-bodies is the most prevalent decay pathway, yet, P-bodies may facilitate not only decay, but also act as a storage ...
Congwei Wang +5 more
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Two- and Three-Dimensional Tracking of MFA2 mRNA Molecules in Mating Yeast
Cells, 2020 Intracellular mRNA transport contributes to the spatio-temporal regulation of mRNA function and localized translation. In the budding yeast, Saccharomyces cerevisiae, asymmetric mRNA transport localizes ~30 specific mRNAs including those encoding ...
Polina Geva +2 more
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Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system [PDF]
, 2015 This work was supported by Medical Research Scotland (FRG353 to VAS), the FP7- Directorate-General for Research and Innovation of the European Commission (EU HEALTHF4-2012-305033 to Coordinating Action Systems Medicine to DJH); the Chief Scientist Office
Smith, V. Anne +7 more
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