Results 71 to 80 of about 110,071 (192)

A Luciferase-Based Approach for Functional Screening of 5′ and 3′ Untranslated Regions of the mRNA Component for mRNA Vaccines

Background/Objectives: The recent COVID-19 pandemic caused by SARS-CoV-2 infection has highlighted the need for protocols for rapid development of efficient screening methods to search for the optimal mRNA vaccine structures against mutable viral agents.
Nikita Shepelev, Diana Malabuiok, Maria Poteshnova, Elena Vodovozova, Yury Prokopenko, Yuliana Mokrushina, Dmitry Andreev, Maria Rubtsova, Yury Rubtsov, Mariya Koryagina, Olga Dontsova, Stanislav Terekhov, Ivan Smirnov, Aleksander Chernov, Alexander Gabibov, Ekaterina Moiseeva   +15 more
core   +1 more source

SARS-CoV-2 mRNA Vaccines: Immunological Mechanism and Beyond

, 2021
To successfully protect against pathogen infection, a vaccine must elicit efficient adaptive immunity, including B and T cell responses. While B cell responses are key, as they can mediate antibody-dependent protection, T cells can modulate B cell ...
Emily Bettini, Michela Locci
core   +1 more source

RNA vaccines: The dawn of a new age for tuberculosis?

Human Vaccines & Immunotherapeutics
Since 2019, there has been a growing focus on mRNA vaccines for infectious disease prevention, particularly following the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Junli Li, Dong Liu, Xiaochi Li, Jiazheng Wei, Weixin Du, Aihua Zhao, Miao Xu   +6 more
doaj   +1 more source

Recent Advances in Messenger Ribonucleic Acid (mRNA) Vaccines and Their Delivery Systems: A Review

, 2023
Wubetu Yihunie,1 Getinet Nibret,1 Yibeltal Aschale2 1Department of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia; 2Department of Medical Laboratory Science, College of Health Sciences, Debre Markos University ...
Yihunie W, Nibret G, Aschale Y
core  

Development of Bivalent mRNA Vaccines against SARS-CoV-2 Variants

, 2022
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected billions of individuals and is the cause of the current global coronavirus disease 2019 (COVID-19) pandemic.
Zihui Fang, Luo, Liping, Yixin Lei, Jianglong Li, Lei, Yixin, Shuang Li, Li, Shuang, Li, Zhi, Jun Liu, Ronglin Xie, Yucai Peng, Liu, Qi, Peng, Yucai, Jing Jin, Liping Luo, Li, Jianglong, Xie, Ronglin, Fang, Zihui, Jin, Jing, Liu, Jun, Qi Liu, Zhi Li   +21 more
core   +1 more source

Local and Systemic Adverse Reactions to mRNA COVID-19 Vaccines Comparing Two Vaccine Types and Occurrence of Previous COVID-19 Infection

, 2021
The aim of this study was to assess adverse reactions to COVID-19 vaccines, comparing the BNT162b2 or the mRNA-1273 COVID-19 vaccines and the presence and seriousness of a previous COVID-19 infection.
Antònia Agustí, Magda Campins, Susana Otero-Romero, Sonia Uriona, Blanca Borras-Bermejo, Yolima Cossio-Gil, Laia Pinós, Xavier Martínez-Gómez, Oleguer Parés-Badell, Cristina Aguilera, José Ángel Rodrigo-Pendás   +10 more
core   +1 more source

mRNA Vaccine Technology Beyond COVID-19

Background/Objectives: Since their approval in early 2020, mRNA vaccines have gained significant attention since the COVID-19 pandemic as a potential therapeutic approach to tackle several infectious diseases.
Florence Akinyi, Sola Oloruntimehin, Michael Paul, Olumuyiwa Ariyo   +3 more
core   +1 more source

mRNA vaccines in tumor targeted therapy: mechanism, clinical application, and development trends

Biomarker Research
Malignant tumors remain a primary cause of human mortality. Among the various treatment modalities for neoplasms, tumor vaccines have consistently shown efficacy and promising potential.
Yu Gao, Liang Yang, Zhenning Li, Xueqiang Peng, Hangyu Li   +4 more
doaj   +1 more source

Malaria Vaccines: From the Past towards the mRNA Vaccine Era

, 2023
Plasmodium spp. is the etiological agent of malaria, a life-threatening parasitic disease transmitted by infected mosquitoes. Malaria remains a major global health challenge, particularly in endemic regions.
Maria E. Tsoumani, Antonia Efstathiou, Chrysa Voyiatzaki   +2 more
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Concomitant administration of seasonal influenza and COVID-19 mRNA vaccines [PDF]

Current clinical guidelines support the concomitant administration of seasonal influenza vaccines and COVID-19 mRNA boosters vaccine. Whether dual vaccination may impact vaccine immunogenicity due to an interference between influenza or SARS-CoV-2 ...
María Del Mar Muñoz-García (17812548), García-Sastre, Adolfo, Escalera, Alba, Salamanca-Rivera, Celia, Jerónimo Pachón (171963), Alba Escalera (17673661), Muñoz-García, M. M., Celia Salamanca-Rivera (17812545), Teresa Aydillo (13943739), Pachón, Jerónimo, Amaya Rojo-Fernandez (17812542), Rojo-Fernández, Amaya, Sánchez-Cordero, María José, Adolfo García-Sastre (51848), Sánchez-Céspedes, Javier, Cordero, Elisa, Javier Sánchez-Céspedes (10724359), Aydillo, Teresa, Maria Balsera-Manzanero (17812539), María José Sánchez-Cordero (17812551), Balsera-Manzanero, María, Elisa Cordero (6997022)   +21 more
core   +2 more sources