Results 61 to 70 of about 110,071 (192)
Developing mRNA-vaccine technologies [PDF]
RNA Biology, 2012 mRNA vaccines combine desirable immunological properties with an outstanding safety profile and the unmet flexibility of genetic vaccines. Based on in situ protein expression, mRNA vaccines are capable of inducing a balanced immune response comprising both cellular and humoral immunity while not subject to MHC haplotype restriction.
Thomas, Schlake +3 more
openaire +2 more sources
The Delivery of mRNA Vaccines for Therapeutics
Life, 2022 mRNA vaccines have been revolutionary in combating the COVID-19 pandemic in the past two years. They have also become a versatile tool for the prevention of infectious diseases and treatment of cancers. For effective vaccination, mRNA formulation, delivery method and composition of the mRNA carrier play an important role. mRNA vaccines can be delivered
Nitika, Jiao Wei, Ai-Min Hui
openaire +3 more sources
Journal of Genetics and Genomics, 2021 The ongoing COVID-19 pandemic and its unprecedented global societal and economic disruptive impact highlight the urgent need for safe and effective vaccines. Taking substantial advantages of versatility and rapid development, two mRNA vaccines against COVID-19 have completed late-stage clinical assessment at an unprecedented speed and reported positive
Huang, Qingrui +2 more
openaire +2 more sources
Reactogenicity of mRNA- and Non-mRNA-Based COVID-19 Vaccines among Lactating Mother and Child Dyads
, 2022 The aims of the study are to: (a) Describe the reactogenicity of WHO-approved two mRNA (Pfizer-BioNTech, Moderna) and two non-RNA (Oxford-AstraZeneca, Sinovac) vaccines among lactating mother and child pairs, and (b) Compare and contrast the ...
Low, Jia Ming +11 more
core +1 more source
Messenger RNA vaccines in the prevention of allergic diseases
World Allergy Organization JournalMessenger RNA (mRNA) vaccines are composed of mRNA sequences encoding pathogens. The first coronavirus mRNA vaccine (BNT162B2, Pfizer/BioNTech), approved in the United Kingdom in 2020, had prevented approximately 20 million deaths globally within the ...
Song Li, MD +2 more
doaj +1 more source
Advanced Drug Delivery Reviews, 2021 mRNA vaccines have evolved from being a mere curiosity to emerging as COVID-19 vaccine front-runners. Recent advancements in the field of RNA technology, vaccinology, and nanotechnology have generated interest in delivering safe and effective mRNA therapeutics. In this review, we discuss design and self-assembly of mRNA vaccines.
Kim, Jeonghwan +3 more
openaire +2 more sources
, 2022 Little was known about Malaysian parental attitudes, beliefs, and intentions surrounding coronavirus disease 2019 (COVID-19) vaccines for children when the National COVID-19 Immunization Program for Children (PICKids) was launched in February 2021.
Li-Ping Wong +7 more
core +1 more source
COVID-19 mRNA vaccines preserve immunogenicity after re-freezing
, 2022 The massive COVID-19 vaccine purchases made by high-income countries have resulted in important sample losses, mainly due to the complexity of their handling.
Maldonado, Rafael, 1961- +7 more
core +1 more source
Recent Advancements in mRNA Vaccines: From Target Selection to Delivery Systems
mRNA vaccines are leading a medical revolution. mRNA technologies utilize the host’s own cells as bio-factories to produce proteins that serve as antigens.
Weilu Sun, Hailong Qi, Zhongyan Wu
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Leveraging an mRNA Platform for the Development of Vaccines Against Egg Allergy
Background: Food allergy (FA) poses a major global health issue due to the increasing prevalence and lack of effective prevention strategies. Allergen-specific immunotherapy (AIT) has emerged as a disease-modifying therapy for FA.
Xianyu Shao +14 more
core +1 more source