Results 81 to 90 of about 2,567 (167)

Knockdown of MSI1 inhibited the cell proliferation of human osteosarcoma cells by targeting p21 and p27

Oncology Letters, 2017
Osteosarcoma is the most common type of primary bone cancer in children and adolescents, but its mechanism remains unclear. Musashi RNA-binding protein 1 (MSI1) is highly expressed in certain cancer types and functions as a putative progenitor/stem cell marker.
Niu, Jianbing, Zhao, Xiulian, Liu, Qingsheng, Yang, Jinsan   +3 more
openaire   +3 more sources

MSI1-FTHL17C-iron circuit couples metabolic and epigenetic control of pluripotency in mouse embryonic stem cells

Cell Regeneration
Maintenance of pluripotency in embryonic stem cells (ESCs) requires coordinated integration of transcriptional, metabolic, and epigenetic programs. Here, we identify a post-transcriptional regulatory axis linking the RNA-binding protein Musashi-1 (MSI1 ...
Qianyan Li, Yi Li, Jiazhen Han, Liming Cheng, Gufa Lin, Youwei Chen   +5 more
doaj   +1 more source

Knockout of RNA Binding Protein MSI2 Impairs Follicle Development in the Mouse Ovary: Characterization of MSI1 and MSI2 during Folliculogenesis

Biomolecules, 2015
Characterizing the mechanisms underlying follicle development in the ovary is crucial to understanding female fertility and is an area of increasing research interest.
Jessie M. Sutherland, Alexander P. Sobinoff, Kara M. Gunter, Barbara A. Fraser, Victoria Pye, Ilana R. Bernstein, Evan Boon, Nicole A. Siddall, Luisa I. De Andres, Gary R. Hime, Janet E. Holt, Thomas Graf, Eileen A. McLaughlin   +12 more
doaj   +1 more source

Knockdown of MSI1 inhibits the proliferation of human oral squamous cell carcinoma by inactivating STAT3 signaling

International Journal of Molecular Medicine, 2019
Musashi RNA‑binding protein 1 (MSI1) is highly expressed in several types of cancer; however, its role in oral squamous cell carcinoma (OSCC) remains unknown. The purpose of this study was to investigate the probable mechanism underlying the involvement of MSI1 in OSCC.
Wang, Chen-Fei, Zhang, Hong-Chuang, Feng, Xin-Mei, Song, Xiao-Meng, Wu, Yu-Nong   +4 more
openaire   +3 more sources

Zika Virus as Oncolytic Therapy for Brain Cancer: Myth or Reality?

Frontiers in Microbiology, 2019
The ability of self-replicating oncolytic viruses (OVs) to preferentially infect and lyse cancer cells while stimulating anti-tumor immunity of the host strongly indicates its value as a new field of cancer therapeutics to be further explored.
Kar Yan Su, Kar Yan Su, Vinod R. M. T. Balasubramaniam   +2 more
doaj   +1 more source

Establishment of Prognostic Models for Astrocytic and Oligodendroglial Brain Tumors with Standardized Quantification of Marker Gene Expression and Clinical Variables

Biomarker Insights, 2010
Background Prognosis models established using multiple molecular markers in cancer along with clinical variables should enable prediction of natural disease progression and residual risk faced by patients.
Yi-Hong Zhou, Kenneth R. Hess, Vinay R. Raj, Liping Yu, Longjian Liu, Alfred W.K. Yung, Mark E. Linskey   +6 more
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

MiR-330-3p inhibits gastric cancer progression through targeting MSI1.

American journal of translational research
Increasing evidences demonstrated that microRNAs (miRNAs) play critical roles in the human tumor development and progression. In our study, we found that miR-330-3p expression was downregulated in gastric cancer cell lines and tissues. Ectopic expression of miR-330-3p suppressed the gastric cancer cell proliferation, colony formation and migration ...
Aoran, Guan, Hui, Wang, Xun, Li, Hui, Xie, Ruotian, Wang, Yankun, Zhu, Ruhong, Li   +6 more
openaire   +1 more source

MSI1 Gene [PDF]

, 2020
openaire   +1 more source

MSI1 wt Allele [PDF]

, 2020
openaire   +1 more source