Results 51 to 60 of about 4,722 (199)

Methylation of the promoter region of the MTRR gene in childhood acute lymphoblastic leukemia

open access: yesOncology Reports, 2019
Epigenetic analysis of the association between the methylation status of the promoter region of the MTRR (5‑methyltetrahydrofolate‑homocysteine methyltransferase reductase) gene and the risk of acute lymphoblastic leukemia (ALL) in children plays an important role in the early diagnosis, assessment of the malignant degree, treatment and evaluation of ...
Jun, Bai   +5 more
openaire   +3 more sources

1H HR‐MAS NMR Metabolomics in Combination With Transcriptomic Correlation Provides New Insights Into Metabolic Heterogeneity Across Breast Cancer Immunohistochemical Subtypes

open access: yesNMR in Biomedicine, Volume 39, Issue 10, October 2026.
Metabolomic profiling of breast cancer tissue using 1H HR‐MAS NMR spectroscopy and LCModel‐based quantitative analysis revealed metabolite differences associated with immunohistochemical subtypes, and subsequent metabolomics–transcriptomics integration linked these subtype‐dependent metabolic signatures to pathways in choline metabolism, one‐carbon ...
Irene Garcia‐Bocanegra   +10 more
wiley   +1 more source

Associations between reduced sperm counts and the most common MTRR haplotypes.

open access: yes, 2013
Associations between reduced sperm counts and the most common MTRR haplotypes.
Jacqueline Mandelbaum (371312)   +11 more
core   +1 more source

Whole‐Genome Sequencing Pilot of the Central Asian Genomic Diversity Project Reveals Distinct Histories, Adaptation, and Introgression

open access: yesAdvanced Science, Volume 13, Issue 53, 24 September 2026.
As a pilot phase of the Central Asian Genomic Diversity Project, whole‐genome sequencing of 166 individuals from 20 Central Asian and Afghan Hazara populations reveals fine‐scale substructure shaped by repeated trans‐Eurasian migration and admixture. Integrated analyses uncover post‐admixture adaptation, archaic introgression, and medically relevant ...
Mengge Wang   +11 more
wiley   +1 more source

The sequencing data of porB, tbpB, 23S rRNA, mtrR and penA genes

open access: yes, 2016
The sequencing data of porB, tbpB, 23S rRNA, mtrR and penA genes in Neisseria ...
Ping, Li   +19 more
core   +1 more source

An Optimized Diagnostic Approach for Adults With Suspected Inherited Metabolic Disorders

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
A multidisciplinary strategy that integrates deep phenotyping with expert genetic interpretation substantially increases the likelihood of reaching a diagnosis in adults suspected of having an IMD. ABSTRACT Inherited metabolic disorders (IMDs) arise from defects in metabolic pathways essential for normal biochemical function.
Machteld M. Oud   +12 more
wiley   +1 more source

Expression of nadA by FarR and MtrR.

open access: yes, 2013
(A–C) Specific activity of β-galactosidase activity of nadA-lacZ in various M7 backgrounds as indicated. Strains over-expressing MtrR marked with a superscript asterisk.
Jason M. Cloward (284427)   +1 more
core   +1 more source

Dueling Regulatory Properties of a Transcriptional Activator (MtrA) and Repressor (MtrR) That Control Efflux Pump Gene Expression in Neisseria gonorrhoeae

open access: yesmBio, 2012
MtrA is a member of the AraC family of transcriptional regulators and has been shown to play an important role in enhancing transcription of the mtrCDE operon, which encodes a tripartite multidrug efflux pump, when gonococci are exposed to a sublethal ...
Yaramah M. Zalucki   +2 more
doaj   +1 more source

An eye on long‐duration spaceflight: Controversies, countermeasures and challenges

open access: yesExperimental Physiology, Volume 111, Issue 9, Page 4004-4014, 1 September 2026.
Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng   +1 more
wiley   +1 more source

Characterization of the Multiple Transferable Resistance Repressor, MtrR, fromNeisseria gonorrhoeae [PDF]

open access: yesJournal of Bacteriology, 2005
ABSTRACTMtrR represses expression of theNeisseria gonorrhoeae mtrCDEmultidrug efflux transporter genes. MtrR displays salt-dependent DNA binding, a stoichiometry of two dimers per DNA site, and, for a protein that was expected to be essentially all helical, a high percentage of random coil and possibly β-sheet structure.
Katherine M, Hoffmann   +3 more
openaire   +2 more sources

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