Results 41 to 50 of about 4,722 (199)
Decreased Azithromycin Susceptibility of Neisseria gonorrhoeae Due to mtrR Mutations [PDF]
Antimicrobial Agents and Chemotherapy, 1999 ABSTRACT Single-dose azithromycin therapy has recently been used in Uruguay for the treatment of uncomplicated gonococcal infections. As part of an active surveillance study to monitor the emergence of antibiotic resistance in gonococcal isolates, we examined the levels of azithromycin susceptibility in 51 consecutive isolates ...
L, Zarantonelli +3 more
openaire +2 more sources
MtrR influences FarR::DNA complexes.
, 2013 Shown is an EMSA evaluating the binding of MtrR–MBP and FarR-MBP to 32P-labeled nadA promoter based on order of protein introduction. Lane assignments from left to right: probe alone; probe plus 1.0 mg MtrR-MBP and increasing amounts of FarR-MBP (0, 0.13,
Jason M. Cloward (284427) +1 more
core +1 more source
Antibiotics, 2023 The aim of this work was to study the resistance to macrolides (azithromycin) in the modern Russian population of N. gonorrhoeae with the analysis of genetic resistance determinants.
Ilya Kandinov +10 more
doaj +1 more source
Analysis of MTR and MTRR Polymorphisms for Neural Tube Defects Risk Association
Medicine, 2015 Neural tube defects (NTDs) are the most common congenital defects of the central nervous system among neonates and the folate status during pregnancy was considered as the most important etiopathogenesis of NTDs. Besides, methionine synthase (MTR) gene and methionine synthase reductase (MTRR) gene were folate metabolism involved genes and had been ...
Wang, Yongxin +7 more
openaire +2 more sources
, 2013 Specific activity of β-galactosidase activity of farR-lacZ in the strains M7 wild-type, ΔmtrR, and ΔmtrR complemented with the native and inducible-promoter alleles (superscript asterisk), respectively.
Jason M. Cloward (284427) +1 more
core +1 more source
International Journal of Infectious Diseases, 2019 Objectives: To analyze the susceptibility of Neisseria gonorrhoeae isolates to penicillin (Pen), cefixime (Cfm), ceftriaxone (Cro), tetracycline (Tet), ciprofloxacin (Cip), azithromycin (Azm), and spectinomycin (Spt), and to verify the presence of ...
Joana Calado +5 more
doaj +1 more source
DNA binding properties of MtrR-MBP.
, 2013 Successive increases of MtrR-MBP incubated with 10 ng mtrCDE (A) or nadA (B) promoter regions to assess binding by gel-shift analysis. Arrow; primary complex of DNA and MtrR-MBP. (C) Competition assays.
Jason M. Cloward (284427) +1 more
core +1 more source
Rheumatology &Autoimmunity, EarlyView.This review integrates clinical, immunological, genetic, and multi‐omic evidence, highlighting dynamic inflammatory and adenosine‐pathway biomarkers and reinforcing treat‐to‐target principles as the most actionable framework for personalized methotrexate therapy.
Joana Ramos Rodrigues +6 more
wiley +1 more source
Distribution of the MTRR A66G polymorphism among populations in China.
, 2016 Distribution of the MTRR A66G polymorphism among populations in China.
Jinjian Fu (381987) +3 more
core +1 more source
Journal of Human Reproductive Sciences, 2022 Context: According to various epidemiological studies, the aetiology of recurrent miscarriages (RMs) is multifactorial. The goal of this study is to learn more about the link between genetic polymorphisms and RM.
Seerat Talwar +6 more
doaj +1 more source