Results 151 to 160 of about 10,037 (206)

Role of mucosal-associated invariant T cells dynamics in pathogenesis of Sjögren syndrome. [PDF]

Sci Rep
Chauffier J, Berger de Gallardo H, Chevalier MF, Kante A, Lambert M, Cabrol X, Aldersons E, Mouly S, Champion K, Amador-Borrero B, Burlacu R, Bigot W, Adle-Biassete H, Kaci R, Selvanadin A, Cohen-Solal M, Coudert A, Caillat-Zucman S, Sène D, Comarmond C.   +19 more
europepmc   +1 more source

Image‐Based Diagnosis of Oral Lesions: Performance of a Vision‐Language Model versus Human Clinicians

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate the real‐world diagnostic performance of a multimodal large language model (LLM) for image‐based assessment of oral mucosal lesions compared with clinicians of varying expertise. Study Design Prospective international multicenter diagnostic accuracy study.
Luigi A. Vaira, Jerome R. Lechien, Fabiola Giudici, Andrea Gasparato, Antonino Maniaci, Andrea De Vito, Fabio Maglitto, Miguel Mayo‐Yáñez, Stefania Troise, Carlos M. Chiesa‐Estomba, Guido Gabriele, Andrea Frosolini, Thomas Radulesco, Fabiana Allevi, Valentino Vellone, Umberto Committeri, Fabrizio Spallaccia, Resi Pucci, Giuseppe Consorti, Giulio Cirignaco, Salvatore Crimi, Marzia Petrocelli, Eleonora M.C. Trecca, Giannicola Iannella, Francesco Laganà, Bernardo Bianchi, Alberto Maria Saibene, Sholem Hack, Paolo Boscolo‐Rizzo, Giovanni M. Soro, Giovanni Salzano, Jerry Polesel, Giacomo De Riu   +32 more
wiley   +1 more source

Single-cell analysis reveals immune remodeling of monocytes, NK cells, T cell exhaustion, and Galectin-9-associated depletion of gamma delta and mucosal-associated invariant T cells in Long COVID with ME/CFS. [PDF]

Front Immunol
Shahbaz S, Bozorgmehr N, Rahmati A, Abouda A, Syed H, Osman M, Elahi S.   +6 more
europepmc   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

The effector function of mucosal associated invariant T cells alters with aging and is regulated by RORγt. [PDF]

Front Immunol
Yang Z, Luo B, Li M, He Z, Ren C, Chen X, Kang X, Chen H, Xu E, Guan W, Xia X.   +10 more
europepmc   +1 more source

Mechanistic Learning for Predicting Survival Outcomes in Head and Neck Squamous Cell Carcinoma

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 540-550, March 2025.
ABSTRACT We employed a mechanistic learning approach, integrating on‐treatment tumor kinetics (TK) modeling with various machine learning (ML) models to address the challenge of predicting post‐progression survival (PPS)—the duration from the time of documented disease progression to death—and overall survival (OS) in Head and Neck Squamous Cell ...
Kevin Atsou, Anne Auperin, Jôel Guigay, Sébastien Salas, Sebastien Benzekry   +4 more
wiley   +1 more source

Betulinic Acid Enema Alleviates Colitis by Targeting Vitamin D Receptor to Protect the Intestinal Mucosal Barrier and Modulate Mucosa‐Associated Microbiota

Phytotherapy Research, EarlyView.
ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with limited effectiveness and safety of current drug therapies. Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid present in traditional Chinese medicines used clinically as retention enemas for UC, but its direct effects and mechanisms remain unclear ...
Lina Dong, Yuanxia Gao, Qian Li, Guangxin Chen, Dong Yang, Liping Zhao, Xiaojing Liu, Shumei Lin   +7 more
wiley   +1 more source

Diagnostic value of mucosal-associated invariant T+ cells combined with inflammatory factors in differentiating chronic rhinosinusitis subtypes with or without nasal polyps. [PDF]

J Med Biochem
Wang Y, Feng Y, Song J, Mou Z.
europepmc   +1 more source

Asymptomatic Violaceous Papules of the Penis in a Patient With HIV

JEADV Clinical Practice, EarlyView.
Jhon Edwin Rodríguez‐Vásquez, Gadwyn Sánchez‐Félix, Joseph Luigi Arzapalo‐Benavides, Adeliza Mariely Manrique‐Vera, Reynaldo Alberto Pomar‐Morante, Celia Betzabet Moisés‐Alfaro   +5 more
wiley   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

Phytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li, Junnan Li, Guangzhi Li, Lili Huang, Tiantian Wen, Yanying Li, Yan Sun, Zhenqiang Liu, Qingshan Chen, Lili Zhang, Tiangang Lu, Ruiyan Wu, Haixue Kuang, Xiaochi Ma, Yan Liu   +14 more
wiley   +1 more source