Results 151 to 160 of about 10,766 (255)
Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden
ChemFoodChem, EarlyView.ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley +1 more source
166 Mucosal-associated invariant T-cells (MAIT) in pancreatic cancer
Journal for ImmunoTherapy of Cancer, 2020 Jéssica Kamiki +7 more
doaj +1 more source
Cancer Nexus, EarlyView.ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang +4 more
wiley +1 more source
RORγt‐APCs: The New Masters of Oral Tolerance
Barrier Immunity, EarlyView.ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley +1 more source
Associations Between Microbial Depletion and Autonomic Dysregulation in Binge‐Eating Disorder
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective The interplay between the gut microbiome and autonomic nervous system remains unexplored in binge‐eating disorder (BED). We aimed to explore specific microbial alterations in BED and examine their potential association with cardiac vagal tone as a distinct bio‐behavioral phenotype.
Shuang Liang +4 more
wiley +1 more source
Fish Scales: A Multifunctional Biomaterial from Nature
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.Fish scales demonstrate nature's solution to impact protection through overlapping multilayered architecture. This biological design combines mineralized surfaces with collagen networks to achieve both flexibility and fracture resistance. The structural principles inspire advanced protective materials and biomedical implants, where damage tolerance ...
Liyao Dong, Xiaojie Sun, Xiguang Chen
wiley +1 more source
Mucosal-associated invariant T cells and the gut-kidney axis: a review. [PDF]
Clin Kidney JZhang X +5 more
europepmc +1 more source
Mucosal-Associated Invariant T Cells in the Digestive System: Defender or Destroyer? [PDF]
Cell Mol Gastroenterol Hepatol, 2023 Zhang H +5 more
europepmc +1 more source
ELECTROPHORESIS, EarlyView.This study improved an HPLC–UV method for quantifying 3‐O‐methylquercetin in porcine nasal mucosa following ICH M10 and ANVISA (Brazil) guidelines, assessing selectivity, linearity, accuracy, precision, and robustness. The method was applied for the first time to evaluate release, permeation, and retention profiles of a nasal formulation.
Jeniffer Viviana Ramirez Hernández +6 more
wiley +1 more source
Discovery of novel, microbial antigens recognised by Mucosal Associated Invariant T cells
Mucosal Associated Invariant T (MAIT) cells are an abundant yet poorly studied type of T cells in humans. Based on our discovery that MAIT cells target pathogens by recognising a by-product of their metabolism, this proposal will identify novel microbial
core