Results 111 to 120 of about 29,467 (217)

Palmitate increased SFA/MUFA ratio in membrane phospholipid and induced UPR in neonatal rat cardiomyocytes.

, 2018
Neonatal rat cardiomyocytes were stimulated by fatty acids (200 μmol/L). (A) Fatty acid composition (mol% of phospholipids) of saturated fatty acid (SFA), monounsaturated fatty acid (MUFA) and the SFA/MUFA ratio after fatty acid stimulation for 6 hours. (
Kaoru Yamashita (5066951), Hiroki Nakanishi (4545331), Keiichi Fukuda (67538), Naohiro Yoshida (479684), Tomohiro Matsuhashi (290906), Shinichi Goto (6069197), Yoshinori Katsumata (630787), Nozomu Kono (211527), Hidenori Moriyama (6069194), Kohsuke Shirakawa (4233655), Masaharu Kataoka (290909), Hiroyuki Arai (37989), Ken Shinmura (328476), Tsunehisa Yamamoto (106999), Jin Endo (4233664), Yuta Shimanaka (6069200), Motoaki Sano (276939), Sarasa Isobe (4233658)   +17 more
core   +1 more source

Causality of unsaturated fatty acids and psoriasis a Mendelian randomization study

Frontiers in Nutrition
BackgroundMany observational studies have identified a link between unsaturated fatty acids and psoriasis. However, they contain reverse causality and confounding factors, and there is no definite causal study between unsaturated fatty acids and ...
Junchen Li, Qian Shen, Chenqi Guo, Yingdong Wang, Yuxiao Ma, Yu Zhang   +5 more
doaj   +1 more source

Entdeckung eines antiviralen Elektronentransferprozesses zur Erzeugung katalytisch selbstversorgender viraler Restriktionsfaktoren

Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.
CYB5R3 wird als mutmaßlicher Elektronentransferpartner von Viperin (RSAD2) identifiziert, was erklärt, warum die ER‐Lokalisation für die antivirale Aktivität erforderlich ist. Dieses Wissen ermöglichte die Entwicklung immunstiller, katalytisch selbstversorgender antiviraler Restriktionsfaktor‐Enzyme (iCAREs), die ein antivirales Nukleosidtriphosphat ...
Mengdi Wu, Nghi Thao Hoang, Deborah Grifagni, Meritxell Wu‐Lu, Yujie Sheng, Theo Situmorang, Pei‐Hsin Tai, Zheng Chen, Astrid Maluta, Mohammed Hakil, Bianca Susini, Hannah Florance, Peter‐Leon Hagedoorn, John Mark Sutton, Maria‐Andrea Mroginski, Simone Ciofi‐Baffoni, Kourosh H. Ebrahimi   +16 more
wiley   +1 more source

A CHO/fibre diet reduces and a MUFA diet increases postprandial lipaemia in type 2 diabetes: no supplementary effects of low-volume physical training.

, 2014
The aim of the study was to evaluate the effects of a supervised physical training added to a healthy diet-rich in either carbohydrate and fibre (CHO/fibre) or monounsaturated fatty acids (MUFA)-on postprandial dyslipidaemia, an independent ...
MANGIONE, ANNA, ANNUZZI, GIOVANNI, VITELLI, ALESSANDRA, P. Cipriano, RIVELLESE, ANGELA ALBAROSA, VIGORITO, CARLO, RICCARDI, GABRIELE, COSTAGLIOLA, Lucia, L. Patti, GIORGINI, Marisa, BOZZETTO, LUTGARDA, ALDERISIO, ANTONIO, STRAZZULLO, ALFONSO, COSTABILE, GIUSEPPINA   +13 more
core   +1 more source

Discovery of an Antiviral Electron Transfer Process to Create Catalytically Self‐Sufficient Viral Restriction Factors

Angewandte Chemie International Edition, Volume 65, Issue 39, 21 September 2026.
CYB5R3 is identified as a putative electron‐transfer partner of viperin (RSAD2), explaining why ER localisation is required for antiviral activity. Its utilisation enabled the engineering of immune‐silent, catalytically self‐sufficient antiviral restriction factor enzymes (iCAREs) that produce an antiviral nucleoside triphosphate analogue (ANTA ...
Mengdi Wu, Nghi Thao Hoang, Deborah Grifagni, Meritxell Wu‐Lu, Yujie Sheng, Theo Situmorang, Pei‐Hsin Tai, Zheng Chen, Astrid Maluta, Mohammed Hakil, Bianca Susini, Hannah Florance, Peter‐Leon Hagedoorn, John Mark Sutton, Maria‐Andrea Mroginski, Simone Ciofi‐Baffoni, Kourosh H. Ebrahimi   +16 more
wiley   +1 more source

Diet effects on the expression of PPARγ2 and enzymes involved in MUFA synthesis.

, 2013
Panel A: Expression of enzymes involved in MUFA synthesis and the nuclear receptor peroxisome proliferator activated receptor γ2 (PPARγ2). Results are represented as mRNA Abundance-Fold Change, relative to chow-fed mice; mean ± SD, n=8/group.
Christopher M. Depner (498478), Gerd Bobe (382976), Donald B. Jump (498480), Kurt M. Bohren (498479), Elizabeth Kensicki (210017), Ginger Milne (366827), Maret G. Traber (127742)   +6 more
core   +1 more source

Egg Peptides From American Shad Extend Lifespan and Healthspan in Caenorhabditis elegans via Lipid Metabolism Remodeling and Antioxidant Defense

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
A novel shad egg peptide (EP) significantly extends Caenorhabditis elegans lifespan through a dual antiaging mechanism. EP systematically remodels lipid metabolism to reinforce cell membranes by promoting beneficial fatty acid biosynthesis and suppressing degradation. Simultaneously, its potent antioxidant activity alleviates oxidative damage, shifting
Jia Du, Qinghua Liu, Zhongxiao Wan, Naomi Sudo, Yanyang Xu   +4 more
wiley   +1 more source

Overexpression of human SCD5 increases the ratio n-7 MUFA to SFA.

, 2013
Neuro2a cells were stably transfected with human SCD5 cDNA in a pCDNA4 expression plasmid (SCD5 cells) or with empty plasmid alone (pCDNA4 cells). Expression of SCD5 was determined by immunoblot analysis of cell homogenates (A).
Debora I. Sinner (318494), R. Ariel Igal (318497), Gregory C. Henderson (318496), Gretchun J. Kim (318495)   +3 more
core   +1 more source

4‐Hydroxytamoxifen induces a noncanonical ferroptosis in lung adenocarcinoma by targeting AKR1B10

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
4‑OHT directly inhibits AKR1B10 enzymatic activity to induce noncanonical ferroptosis in LUAD. AKR1B10 sustains LUAD survival by stabilising ACC1 and detoxifying reactive carbonyl species (RCSs). Nanatinostat similarly targets AKR1B10 and elicits the same cell death modality.
Hui Yang, Yanan Wang, Jiangbo Jin, Hanyan Xu, Yinshui Miao, Xiaojing Wu, Shengsong Chen, Tianyu Han, Qingyuan Zhan   +8 more
wiley   +1 more source

Nutritional content of phytoplankton communities under ice

Ecosphere, Volume 17, Issue 9, September 2026.
Abstract The effects of winter environmental conditions on lake ecology can be highly variable. Ice and overlying snow isolate the water below, impeding exchange of materials among water, atmosphere, and the watershed. Even with these limitations, biological communities under the ice can persist, where cold‐tolerant taxa can be especially abundant ...
Michael F. Meyer, Stephanie E. Hampton, Matthew R. Brousil, Joshua A. Culpepper, Hilary A. Dugan, Aaron W. E. Galloway, Noah R. Lottig, Stephen M. Powers, Sapna Sharma, Kirill Shchapov   +9 more
wiley   +1 more source