Results 21 to 30 of about 3,358,336 (306)

Vaccinomics to Design a Multi-Epitopes Vaccine for Acinetobacter baumannii

International Journal of Environmental Research and Public Health, 2022
Antibiotic resistance (AR) is the result of microbes’ natural evolution to withstand the action of antibiotics used against them. AR is rising to a high level across the globe, and novel resistant strains are emerging and spreading very fast. Acinetobacter baumannii is a multidrug resistant Gram-negative bacteria, responsible for causing severe ...
Miraj ud-din, Aqel Albutti, Asad Ullah, Saba Ismail, Sajjad Ahmad, Anam Naz, Muhammad Khurram, Mahboob ul Haq, Zobia Afsheen, Youness El Bakri, Muhammad Salman, Bilal Shaker, Muhammad Tahir ul Qamar   +12 more
openaire   +2 more sources

Schematic representation of the selection and validation of new putative immunogenic targets and multi-epitope-based vaccines against P. aeruginosa strain 24Pae112 using reverse vaccinology approaches and bioinformatics tools.

, 2023
All criteria and thresholds are shown in the flowchart. OMPs, outer membrane proteins; MEVs, multi-epitope vaccines.
Behnoush Khasheii (16748697), Mahdi Torkamaneh (16748694), Narjes Noori Goodarzi (13531555), Fatemeh Haririzadeh Jouriani (16748691), Farzad Badmasti (9327920), Sepideh Fereshteh (13531558)   +5 more
core   +1 more source

Additional file 1 of Design of a multi-epitope-based peptide vaccine against the S and N proteins of SARS-COV-2 using immunoinformatics approach

, 2022
Additional file 1. Design of a multi-epitope-based peptide vaccine against the S and N proteins of SARS -COV-2 using Immunoinformatics Approach. ( http://galaxy.seoklab.org/cgi-bin/report_REFINE.cgi?key=27ac3cd2f0bd1f0372ce673a67eac9e1 , https://npsa ...
Farnaz Kheirandish (805358), Seyedeh Zeinab Hosseini (12044459), Arian Karimi Rouzbahani (12044456)   +2 more
core   +1 more source

Exploring YidR Gene from Klebsiella pneumoniae To Design a Multi-epitope Vaccine Using Immunoinformatics Approach

Journal of Experimental Life Science, 2022
Klebsiella pneumoniae is the main leading cause of hospital-acquired infection, leading to severe infections such as pneumonia and urinary tract infection.
Maulana Wildan Seputra, Hani Susiati, Tri Yudani Mardining Raras   +2 more
doaj   +1 more source

Multi-epitope vaccine candidate design for dengue virus

Bioinformation, 2023
Dengue Fever (DF) is a vector-borne neglected viral disease with a high burden in the sub-tropics of Asia and Africa. Aedes aegypti is responsible for 90% of cases in the global burden of disease. The primary goal of the treatment is to eliminate the virus from the bloodstream of affected individuals.
Dharani, A, Ezhilarasi, DR, Priyadarsini, G, Abhinand, PA   +3 more
openaire   +2 more sources

Immunogenicity of a multi-epitope DNA vaccine against hantavirus [PDF]

Human Vaccines & Immunotherapeutics, 2012
Hemorrhagic fever with renal syndrome (HFRS) is a severe epidemic disease caused by hantaviruses including Hantaan virus (HTNV), Seoul virus (SEOV), Dobrava virus (DOBV) and Puumala virus. Three of the four HFRS hantaviruses, HTNV, SEOV, and PUUV are found in China. Currently, there is no effective strategy available to reduce infection risk.
Chen, Zhao, Ying, Sun, Yujie, Zhao, Si, Wang, Tongtong, Yu, Feng, Du, X Frank, Yang, Enjie, Luo   +7 more
openaire   +2 more sources

Computational Design and Analysis of a Multi-epitope Against Influenza A virus [PDF]

International Journal of Peptide Research and Therapeutics, 2021
Influenza A viruses are among the most studied viruses, however no effective prevention against influenza infection has been developed. So, designing an effective vaccine against Influenza A virus is a critical issue in the field of medical biotechnology.
Samaneh Rostaminia, Seyed Soheil Aghaei, Behrokh Farahmand, Raziye Nazari, Amir Ghaemi   +4 more
openaire   +2 more sources

Design and Evaluation of a Multi-Epitope Peptide of Human Metapneumovirus [PDF]

Intervirology, 2015
<b><i>Objectives:</i></b> No licensed vaccines or therapeutic agents for human metapneumovirus (hMPV) infection exist to date. We aimed to construct a multi-epitope peptide (MEP) of hMPV to show promising results for epitope-based vaccine development. <b><i>Methods:</i></b> Six independent algorithms were
Xiaoyan, Li, Liru, Guo, Mei, Kong, Xu, Su, Dongjing, Yang, Ming, Zou, Yinghua, Liu, Likun, Lu   +7 more
openaire   +2 more sources

Retinal S-antigen Th1 cell epitope mapping in patients with Behcet's disease [PDF]

, 2009
Background - Retinal S-antigen (S-Ag) is a most characterized autoantigen of autoimmune uveitis. The recognized immunodominant epitope of human S-Ag in patients with uveitis has not been identified. In this study, we selected certain patients with active
Yang, P.Z., Du, L.P., Zhao, C.L., Lin, X.M., He, H., Zhou, H.Y., Kijlstra, A.   +6 more
core   +1 more source

A Candidate multi-epitope vaccine against SARS-CoV-2 [PDF]

Scientific Reports, 2020
Abstract In the past two decades, 7 coronaviruses have infected the human population, with two major outbreaks caused by SARS-CoV and MERS-CoV in the year 2002 and 2012, respectively. Currently, the entire world is facing a pandemic of another coronavirus, SARS-CoV-2, with a high fatality rate.
Kar Tamalika, Narsaria Utkarsh, Basak Srijita, Deb Debashrito, Castiglione Filippo, Mueller David M, Srivastava Anurag P   +6 more
openaire   +6 more sources