Results 31 to 40 of about 3,358,336 (306)

Expression of a Novel HIV-1 Gag-Pol-Env-Nef-Rev Multi-Epitope Construct in Escherichia coli [PDF]

Journal of Medical Microbiology and Infectious Diseases, 2021
Introduction: Recombinant subunit vaccines have been explored against various human pathogens, however, developing an effective therapeutic toward human immunodeficiency virus (HIV) infection has been challenging.
Elahe Akbari, Soheila Ajdari, Esmat Mirabzadeh Ardakani, Elnaz Agi, Vahid Khalaj, Azam Bolhassani   +5 more
doaj  

Designing a multi-epitope vaccine to control porcine epidemic diarrhea virus infection using immunoinformatics approaches

Frontiers in Microbiology, 2023
Porcine epidemic diarrhea virus (PEDV), a continuously evolving pathogen, causes severe diarrhea in piglets with high mortality rates. However, current vaccines cannot provide complete protection against PEDV, so vaccine development is still necessary ...
Wei Hou, Heqiong Wu, Sibei Wang, Wenting Wang, Bin Wang, Bin Wang, Haidong Wang   +6 more
doaj   +1 more source

Various features of multi-epitope vaccines.

, 2022
Various features of multi-epitope vaccines.
Sohrab Najafipour (13531684), Ebrahim Barzegari (3301023), Saade Abdalkareem Jasim (12178300), Esmaeil Behmard (4845154), Amin Kouhpayeh (13531693), Hussein T. Abdulabbas (13531681), Abdolmajid Ghasemian (13531687), Akbar Farjadfar (13531690), Parviz Abdolmaleki (9078721)   +8 more
core   +1 more source

Enhancement of Tetravalent Immune Responses to Highly Conserved Epitopes of a Dengue Peptide Vaccine Conjugated to Polystyrene Nanoparticles

Vaccines, 2020
Vaccination remains the major approach to the prevention of dengue. Since the only licensed live attenuated vaccine (LAV) lacked efficacy against all four serotypes, other vaccine platforms, such as synthetic peptide vaccines, should be explored. In this
Yanqi Chan, Seyed Davoud Jazayeri, Babu Ramanathan, Chit Laa Poh   +3 more
doaj   +1 more source

Immune Responses to Orally Administered Recombinant Lactococcus lactis Expressing Multi-Epitope Proteins Targeting M Cells of Foot-and-Mouth Disease Virus

Viruses, 2021
Foot and mouth disease virus (FMDV), whose transmission occurs through mucosal surfaces, can also be transmitted through aerosols, direct contact, and pollutants. Therefore, mucosal immunity can efficiently inhibit viral colonization.
Fudong Zhang, Zhongwang Zhang, Xian Li, Jiahao Li, Jianliang Lv, Zhongyuan Ma, Li Pan   +6 more
doaj   +1 more source

Protection against H1N1 influenza challenge by a DNA vaccine expressing H3/H1 subtype hemagglutinin combined with MHC class II-restricted epitopes

Virology Journal, 2010
Background Multiple subtypes of avian influenza viruses have crossed the species barrier to infect humans and have the potential to cause a pandemic. Therefore, new influenza vaccines to prevent the co-existence of multiple subtypes within a host and ...
Tian Mingyao, Zhang Dan, Lu Huijun, Tan Lei, Hu Bo, Wang Zhuoyue, Jin Ningyi   +6 more
doaj   +1 more source

Design and Assessment of a Novel In Silico Approach for Developing a Next-Generation Multi-Epitope Universal Vaccine Targeting Coronaviruses

Microorganisms, 2023
In the past two decades, there have been three coronavirus outbreaks that have caused significant economic and health crises. Biologists predict that more coronaviruses may emerge in the near future.
Muhammad Asif Rasheed, Sohail Raza, Wadi B. Alonazi, Muhammad Adnan Ashraf, Muhammad Tariq Navid, Irfana Aslam, Muhammad Nasir Iqbal, Sarfraz Ur Rahman, Muhammad Ilyas Riaz   +8 more
doaj   +1 more source

Computational Design of a Multi-Epitope Vaccine Against Porphyromonas gingivalis [PDF]

Frontiers in Immunology, 2022
Porphyromonas gingivalisis a Gram-negative pathogenic bacterium associated with chronic periodontitis. The development of a chimeric peptide-based vaccine targeting this pathogen could be highly beneficial in preventing oral bone loss as well as other severe gum diseases.
Bilal Shaker, Sajjad Ahmad, Junhao Shen, Hyung Wook Kim, Dokyun Na   +4 more
openaire   +3 more sources

The physicochemical properties of a multi-epitope vaccine.

, 2023
The physicochemical properties of a multi-epitope vaccine.
Shahin Nazarian (9192158), Sajjad Ahmad (768814), Hamidreza Pazoki-Toroudi (10879906), Mahdi Ghatreh Samani (15852860), Elham Raeisi (15852857), Samira Sanami (13192454), Muhammad Tahir ul Qamar (9269536), Shahram Tahmasebian (14233182), Maryam Fazeli (3171162)   +8 more
core   +1 more source

Epitope-Directed Antibody Elicitation by Genetically Encoded Chemical Cross-Linking Reactivity in the Antigen

, 2023
No current methods can selectively elicit an antibody response to a specific conformational epitope in a whole antigen in vivo. Here, we incorporated Nε-acryloyl-l-lysine (AcrK) or Nε-crotonyl-l-lysine (Kcr) with cross-linking activities into the ...
Liang Xu (102656), Weiping Wu (534670), Yinjian Zhou (16028715), Shengwang Dai (7352774), Jay Zhang (422679), Yuhan Zhang (2792089), Shuang Liu (8449), Shuqin Xiang (16028712), Zihan Zhang (3117441), Chaoyang Zhu (2635984), Chengxiang Li (5278343), Hui Guo (110581), Feng Wang (44414), Longxin Chen (380248)   +13 more
core   +2 more sources