Results 61 to 70 of about 3,358,336 (306)

Image_2_The long multi-epitope peptide vaccine combined with adjuvants improved the therapeutic effects in a glioblastoma mouse model.tiff

open access: yes, 2022
Emerging data have suggested that single short peptides have limited success as a cancer vaccine; however, extending the short peptides into longer multi-epitope peptides overcame the immune tolerance and induced an immune response.
Tae-Kyu Lee (14078589)   +12 more
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

In silico designing of a recombinant multi-epitope antigen for leprosy diagnosis

open access: yesJournal of Genetic Engineering and Biotechnology, 2022
Leprosy is caused by Mycobacterium leprae and Mycobacterium lepromatosis. Most of the affected population lives in low-income countries and may take up to 10 years to show any clinical signs, which is how physicians diagnose it. However, due to progressive cell damage, early diagnosis is very important.
Marcela Rezende Lemes   +10 more
openaire   +3 more sources

Discontinuous Epitope Mapping of Antibodies Using Bacterial Cell Surface Display of Folded Domains

open access: yes, 2018
Knowledge of the exquisite-binding surface of an antibody on its target protein is of great value, in particular for therapeutic antibodies for understanding method of action and for stratification of patients carrying the necessary epitope for desired ...
Rockberg, Johan,   +3 more
core   +1 more source

Image_3_The long multi-epitope peptide vaccine combined with adjuvants improved the therapeutic effects in a glioblastoma mouse model.tif

open access: yes, 2022
Emerging data have suggested that single short peptides have limited success as a cancer vaccine; however, extending the short peptides into longer multi-epitope peptides overcame the immune tolerance and induced an immune response.
Tae-Kyu Lee (14078589)   +12 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

DataSheet_1_The long multi-epitope peptide vaccine combined with adjuvants improved the therapeutic effects in a glioblastoma mouse model.zip

open access: yes, 2022
Emerging data have suggested that single short peptides have limited success as a cancer vaccine; however, extending the short peptides into longer multi-epitope peptides overcame the immune tolerance and induced an immune response.
Tae-Kyu Lee (14078589)   +12 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Epitope-specific antibody responses in gD2 immunized guinea pigs and humans.

open access: yes, 2018
Epitope-specific antibody responses in gD2 immunized guinea pigs and humans.
Harvey M. Friedman (3682018)   +7 more
core   +1 more source

trypanosomatics/The-Chagas-Disease-Antigen-and-Epitope-Atlas: v1.0.0

open access: yes, 2023
A Trypanosoma cruzi Antigen and Epitope Atlas: deep characterization of individual antibody specificities in human Chagas Disease patients across the ...
Alejandro   +2 more
core   +1 more source

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