Results 211 to 220 of about 26,762 (251)

Desosamine in multicomponent reactions

Bioorganic & Medicinal Chemistry Letters, 2006
Desosamine occurring ubiquitously in natural products is introduced into isocyanide based multicomponent reaction chemistry. Corresponding products are of potential interest for the design of novel antibiotics.
Achatz, Sepp, Dömling, Alexander
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Photoinduced Multicomponent Reactions

Angewandte Chemie International Edition, 2016
AbstractThe combination of multicomponent approaches with light‐driven processes opens up new scenarios in the area of synthetic organic chemistry, where the need for sustainable, atom‐ and energy‐efficient reactions is increasingly urgent. Photoinduced multicomponent reactions are still in their infancy, but significant developments in this area are ...
GARBARINO, SILVIA, Ravelli, Davide, Protti, Stefano, BASSO, ANDREA   +3 more
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Multicomponent Reactions with Isocyanides

Angewandte Chemie, 2000
Multicomponent reactions (MCRs) are fundamentally different from two-component reactions in several aspects. Among the MCRs, those with isocyanides have developed into popular organic-chemical reactions in the pharmaceutical industry for the preparation of compound libraries of low-molecular druglike compounds.
, Dömling, , Ugi
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Multicomponent Reactions

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Arounarith Tuch, Stefan Walle
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Multicomponent Reactions and Multicomponent Cascade Reactions for the Synthesis of Sequence‐Controlled Polymers

Macromolecular Rapid Communications, 2018
AbstractControl over the monomer sequence during polymerization has attracted great attention in polymer science, but it remains a serious challenge. Recently, multicomponent reactions have been playing a significant role in the synthesis of sequence‐controlled polymers due to their inherent advantage of combining three or more starting materials in ...
Ze, Zhang, Yezi, You, Chunyan, Hong
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Multicomponent Reactions in the Synthesis of Antiviral Compounds

Current Medicinal Chemistry, 2022
Background:Multicomponent reactions are one-pot processes for the synthesis of highly functionalized hetero-cyclic and hetero-acyclic compounds, often endowed with biological activity.Objective:Multicomponent reactions are considered green processes with a high atom economy. In addition, they present advantages compared to the classic synthetic methods,
Lorenzo Botta, Cesarini, Silvia, Zippilli, Claudio, Bizzarri, Bruno Mattia, Fanelli, Angelica, Saladino, Raffaele   +5 more
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Borylated reagents for multicomponent reactions

Drug Discovery Today: Technologies, 2018
Over the past two decades, there has been an increasing interest in the therapeutic potential of organoboron reagents due to the discovery of bortezomib (Velcade). This has motivated synthetic chemists to develop novel routes for the preparation of heteroatom-rich boron-containing molecules (BCMs).
Joanne, Tan, Andrei K, Yudin
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Nonracemizable Isocyanoacetates for Multicomponent Reactions

The Journal of Organic Chemistry, 2008
Chiral ortho esters of alpha-isocyano acids were synthesized from commercially available Cbz-protected alpha-amino acids. These compounds are stable toward racemization in the Ugi 4CC in contrast to known esters of alpha-isocyano acids. Applying them in Ugi 4CC with subsequent deprotection gives access to dipeptides with preserved configuration at the ...
Alexander G, Zhdanko, Valentine G, Nenajdenko   +1 more
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Multicomponent reactions for the synthesis of pyrroles

Chemical Society Reviews, 2010
Multicomponent reactions are one of the most interesting concepts in modern synthetic chemistry and, as shown in this critical review, they provide an attractive entry into pyrrole derivatives, which are very important heterocycles from many points of view including medicinal and pharmaceutical chemistry and materials science (97 references).
Verónica, Estévez, Mercedes, Villacampa, J Carlos, Menéndez   +2 more
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Multicomponent Reactions of Convertible Isonitriles

The Journal of Organic Chemistry, 2009
A new family of unsaturated isonitriles has been prepared by the base-promoted ring-opening of oxazoles, offering an alternative to the conventional formamide dehydration route. These compounds undergo the full complement of multicomponent reactions for which isonitriles are known and offer the desirable trait of giving amide products that readily ...
Michael C, Pirrung, Subir, Ghorai, Tannya R, Ibarra-Rivera   +2 more
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