Results 151 to 160 of about 465,638 (353)

Detection of Escherichia coli Enteropathogens by Multiplex Polymerase Chain Reaction from Children's Diarrheal Stools in Two Caribbean–Colombian Cities

, 2009
Oscar G. Gómez‐Duarte, Octavio Arzuza, Delfina Urbina, Jing Bai, Julio A. Guerra, Oscar Montes, Marta Puello, Ketty Mendoza, Gregorio Y. Castro   +8 more
openalex   +1 more source

Macrophage–Derived Ferritin Exacerbates Silica‐Induced Pulmonary Fibrosis via PIK3R2‐Mediated Fibroblast Differentiation

Advanced Science, EarlyView.
This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang, Xuxi Chen, Hongying Quan, Rui Qian, Shuyu Gong, Qiurong He, Ying Gao, Ajia Axi, Manyu Zhao, Qin Zhang, Ling Zhang, Lijun Peng, Xin Sun, Ben Zhang, Yuqin Yao   +14 more
wiley   +1 more source

Novel multiplex polymerase chain reaction and an oligonucleotide array for specific detection of the dominant foodborne bacterial pathogens in chicken meat [PDF]

, 2013
Kupradit Chanida, Ruamkuson Darawan, Sureelak Rodtong, Ketudat Cairns Mariena   +3 more
openalex   +1 more source

Ultrafast Dense Immobilization of Noble Metal Nanoparticles on Customizable Multifunctional Polymer Microspheres for Heterogeneous Catalysis and Multiplexed Biodetection

Advanced Science, EarlyView.
This work proposes a facile co‐assembly strategy to achieve highly uniform and dense immobilization of diverse noble metal nanoparticles onto metastable multifunctional (e.g., magnetic or fluorescent) polymer microspheres, enabling fabrication of complex hierarchical superstructures.
Jie Zhao, Xinyi Liu, Dan Li, Xuefei Jing, Weijie Wu, Liangrui He, Yizhang Tang, Zhen Liu, Yulin Zeng, Haitian Sha, Huibin Qiu, Xujiang Yu, Wanwan Li   +12 more
wiley   +1 more source

Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai, Guihong Pan, Xixi Feng, Jun Zhang, Yunxia Li, Shanmeizi Zhao, Zhenming Lin, Yun Feng, Wei Bao, Hongyan Yang, Chengmei Xie, Chen Huang, Jun Wang   +12 more
wiley   +1 more source

Development and validation of a multiplex polymerase chain reaction assay for detection of the five families of plasmid-encoded colistin resistance.

International Journal of Antimicrobial Agents, 2019
A. Jousset, Sandrine Bernabeu, R. Bonnin, Elodie Creton, Garance Cotellon, Aimie Sauvadet, T. Naas, L. Dortet   +7 more
semanticscholar   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

Varicella zoster virus-associated anterior uveitis in a seronegative adult without a history of chickenpox

Clinical Ophthalmology, 2015
Izumi Mine, Sho Ishikawa, Masaru TakeuchiDepartment of Ophthalmology, National Defense Medical College, Tokorozawa City, Saitama, JapanAim: The aim of this report was to present a case of varicella zoster virus (VZV)-associated anterior uveitis, which ...
Mine I, Ishikawa S, Takeuchi M
doaj  

Peer Review #2 of "A rapid and accurate method for the detection of four aminoglycoside modifying enzyme drug resistance gene in clinical strains of Escherichia coli by a multiplex polymerase chain reaction (v0.2)"

, 2020

openalex   +1 more source