Results 81 to 90 of about 4,566 (189)
Rigidly connected multispecific artificial binders with adjustable geometries [PDF]
, 2017 Multivalent binding proteins can gain biological activities beyond what is inherent in the individual binders, by bringing together different target molecules, restricting their conformational flexibility or changing their subcellular localization.
Alexander Batyuk +5 more
core +2 more sources
Ilmu Kelautan, 2013 Perairan laut tropis seperti di Indonesia yang memiliki variasi lingkungan yang hampir konstan– diduga periode pemijahan karang melebar sampai beberapa bulan dan pada fase bulan yang berbeda, sehingga sulit menentukan waktu pemijahannya dalam skala bulan,
Syafyudin Yusuf +3 more
doaj +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.ABSTRACT As diabetes has become an important public health issue, Lonicerae Japonicae Flos (LJF) had gradually attracted increasing attention on diabetes. This study aimed to investigate the hypoglycemic ingredients and underlying mechanisms of LJF in diabetes using an integrated strategy of network pharmacology, molecular docking and experimental ...
Zhang Nan +5 more
wiley +1 more source
Experiments with defined multispecific coccidial infections in lambs
Parasitology, 1976 The behaviour of four species of Eimeria was studied in lambs which were given either monospecific or multispecific infections. In the presence of other species the patency of oocyst production of E. ovina and E. weybridgensis was extended and the total number of oocysts produced by all species except E. ninakohlyakimovae was increased.
J, Catchpole, C C, Norton, L P, Joyner
openaire +2 more sources
NK Cell Activation by Platinum Boosts Immunotherapy in HR+/HER2− Breast Cancer
Advanced Science, Volume 13, Issue 20, 9 April 2026.Multi‐omics and single‐cell analyses identify activated NK cells as key mediators of anti‐PD‐(L)1 response in HR+/HER2− breast cancer. Platinum chemotherapy enhances NK cell cytotoxicity through NF‐κB–associated signaling, synergizing with immunotherapy and providing a rationale for combination treatment.
Yi‐Yu Chen +8 more
wiley +1 more source
Molecular Mechanism of Ochratoxin A Transport in the Kidney
Toxins, 2010 The mycotoxin, ochratoxin A (OTA), is thought to be responsible for Balkan endemic nephropathy. OTA accumulates in several tissues, especially in the kidneys and liver.
Naohiko Anzai +2 more
doaj +1 more source
Taxonomic Complexity and Conservation Implications of Mediterranean Mesophotic Rhodolith Beds
Aquatic Conservation: Marine and Freshwater Ecosystems, Volume 36, Issue 4, April 2026.ABSTRACT Rhodolith beds are bioconstructions formed by coralline algae (Rhodophyta: Corallinophycidae) and are ecologically important worldwide because they provide habitats that support diverse biocenoses. However, conservation efforts are limited by gaps in our knowledge of their spatial distribution and species composition.
Andrea Cabrito +3 more
wiley +1 more source
, 1994 Bile is an important excretory route for the elimination of amphiphilic organic anions, and hepatocytes are the primary secretory units of bile formation.
JANSEN, PLM, ELFERINK, RPJO
core +1 more source
Context‐Dependent Chemoselectivity of Aromatic C‐Methyltransferases
ChemBioChem, Volume 27, Issue 8, April 2026.Chemoselectivity is context‐dependent: The SAM‐dependent C‐MTs SfmM2 and NapB5 from streptomycetes catalyze the C‐ and/or O‐dimethylation of aromatic substrates, including l‐tyrosine and flavonoids. C‐methylation activity requires precise substrate recognition and positioning to ensure proximity between the target carbon nucleophile and the methyl ...
Juliane Breiltgens +4 more
wiley +1 more source