Results 61 to 70 of about 1,599 (196)

msBiodat analysis tool, big data analysis for high-throughput experiments [PDF]

, 2016
Background Mass spectrometry (MS) are a group of a high-throughput techniques used to increase knowledge about biomolecules. They produce a large amount of data which is presented as a list of hundreds or thousands of proteins.
Belužić, Robert, Grbeša, Ivana, Muñoz-Torres, Pau M., Rokić, Filip, Vugrek, Oliver   +4 more
core   +3 more sources

Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit [PDF]

The American Journal of Pathology, 2016
The conserved RNA-binding protein Musashi1 (MSI1) has been characterized as a stem cell marker, controlling the balance between self-renewal and differentiation and as a key oncogenic factor in numerous solid tumors, including glioblastoma. To explore the potential use of MSI1 targeting in therapy, we studied MSI1 in the context of radiation ...
Patricia Rosa, de Araujo, Aparna, Gorthi, Acarizia E, da Silva, Sonal S, Tonapi, Dat T, Vo, Suzanne C, Burns, Mei, Qiao, Philip J, Uren, Zhi-Min, Yuan, Alexander J R, Bishop, Luiz O F, Penalva   +10 more
openaire   +2 more sources

Alteration of Musashi1 Intra-cellular Distribution During Regeneration Following Gentamicin-Induced Hair Cell Loss in the Guinea Pig Crista Ampullaris

Frontiers in Cellular Neuroscience, 2019
The mechanism underlying hair cell (HC) regeneration in the mammalian inner ear is still under debate. Understanding what molecules regulate the HC regeneration in mature mammals will be the key to the treatment of the inner ear disorder. Musashi1 (MSI1)
Makoto Kinoshita, Chisato Fujimoto, Shinichi Iwasaki, Akinori Kashio, Yayoi S. Kikkawa, Kenji Kondo, Hideyuki Okano, Tatsuya Yamasoba   +7 more
doaj   +1 more source

Musashi-1 and miR-147 Precursor Interaction Mediates Synergistic Oncogenicity Induced by Co-Infection of Two Avian Retroviruses

Cells, 2022
Synergism between avian leukosis virus subgroup J (ALV-J) and reticuloendotheliosis virus (REV) has been reported frequently in co-infected chicken flocks.
Defang Zhou, Longying Ding, Menglu Xu, Xiaoyao Liu, Jingwen Xue, Xinyue Zhang, Xusheng Du, Jing Zhou, Xiyao Cui, Ziqiang Cheng   +9 more
doaj   +1 more source

Leptin Regulation of Gonadotrope Gonadotropin-Releasing Hormone Receptors As a Metabolic Checkpoint and Gateway to Reproductive Competence

Frontiers in Endocrinology, 2018
The adipokine leptin signals the body’s nutritional status to the brain, and particularly, the hypothalamus. However, leptin receptors (LEPRs) can be found all throughout the body and brain, including the pituitary.
Angela K. Odle, Noor Akhter, Mohsin M. Syed, Melody L. Allensworth-James, Helen Beneš, Andrea I. Melgar Castillo, Melanie C. MacNicol, Angus M. MacNicol, Gwen V. Childs   +8 more
doaj   +1 more source

Musashi-1 promotes cancer stem cell properties of glioblastoma cells via upregulation of YTHDF1

Cancer Cell International, 2020
Background Glioblastoma (GBM) is the most lethal brain tumor characterized by high morbidity and limited treatment options. Tumor malignancy is usually associated with the epigenetic marks, which coordinate gene expression to ascertain relevant ...
Aliaksandr A. Yarmishyn, Yi-Ping Yang, Kai-Hsi Lu, Yi-Chen Chen, Yueh Chien, Shih-Jie Chou, Ping-Hsing Tsai, Hsin-I. Ma, Chian-Shiu Chien, Ming-Teh Chen, Mong-Lien Wang   +10 more
doaj   +1 more source

Mammary stem cell research in veterinary science : an update [PDF]

, 2013
The mammary gland is an organ with a remarkable regenerative capacity that can undergo multiple cycles of proliferation, lactation, and involution. Growing evidence suggests that these changes are driven by the coordinated division and differentiation of
Borena, Bizunesh Mideksa, Burvenich, Christian, Bussche, Leen, Duchateau, Luc, Van de Walle, Gerlinde   +4 more
core   +1 more source

Noncanonical Adult Human Neurogenesis and Axonal Growth as Possible Structural Basis of Recovery From Traumatic Vegetative State

Clinical Medicine Insights: Case Reports, 2017
Patient recovering from traumatic vegetative state has suddenly died from cardiac arrest. In-life improvement of consciousness appeared after reduction of generalized spasticity due to botulinum toxin administration.
Yulia Vainshenker, Vsevolod Zinserling, Alexander Korotkov, Svyatoslav Medvedev   +3 more
doaj   +1 more source

WNT and NOTCH signaling pathways as activators for epidermal growth factor receptor in esophageal squamous cell carcinoma

Cellular & Molecular Biology Letters, 2018
Background Esophageal squamous cell carcinoma (ESCC) is the most common histological type of esophageal cancer, with a poor prognosis. Deregulation of WNT and NOTCH signaling pathways is important in ESCC progression, which can be due to either ...
Mohammad Reza Abbaszadegan, Anali Riahi, Mohammad Mahdi Forghanifard, Meysam Moghbeli   +3 more
doaj   +1 more source

Wnt signalling in intestinal stem cells: lessons from mice and flies [PDF]

, 2018
Adult stem cells play critical roles in the basal maintenance of tissue integrity, also known as homeostasis, and in tissue regeneration following damage. The highly conserved Wnt signalling pathway is a key regulator of stem cell fate.
Carroll, Lynsey, Cordero, Julia, Perochon, Jessica   +2 more
core   +2 more sources