Results 81 to 90 of about 71,509 (231)
Agonist‐induced down‐regulation of m1 muscarinic receptors and reduction of their mRNA level in a transfected cell line [PDF]
, 1990 Shou Zhen Wang +5 more
openalex +1 more source
Andrology, EarlyView.Abstract Couple infertility is a very ancient medical condition. One of the first descriptions of familial infertility/subfertility is contained in the first book of the Bible, Genesis, written in the 10th century BC and reporting tales from the oral tradition even occurred about 800 years earlier.
Manuela Simoni +2 more
wiley +1 more source
Distribution of Muscarinic Acethylcholine Receptors and Related Signal [PDF]
Türk Biyokimya Dergisi, 2006 Muscarinic receptors are members of G protein coupled receptor family. Molecularcloning studies indicate five intronless genes that encode five muscarinic receptorglycoproteins.
Hülya Cabadak
doaj
ANTAGONIST DISCRIMINATION BETWEEN GANGLIONIC AND ILEAL MUSCARINIC RECEPTORS [PDF]
, 1980 David A. Brown, A. FORWARD, S. Marsh
openalex +1 more source
Vasoreactivity as a Measure of Kidney Viability During Ex Vivo Normothermic Machine Perfusion
Artificial Organs, EarlyView.This study aimed to investigate the influence of warm ischemic injury on renal vascular responsiveness to vasoactive drugs during normothermic machine perfusion (NMP). We found that the vascular responses to dopamine and norepinephrine could be used as objective indicators to assess kidney viability during NMP.
Isa M. van Tricht +4 more
wiley +1 more source
Agonist-selective activation of individual G-proteins by muscarinic receptors
Scientific ReportsSelective activation of individual subtypes of muscarinic receptors is a promising way to safely alleviate a wide range of pathological conditions in the central nervous system and the periphery as well.
Dominik Nelic +8 more
doaj +1 more source
Scientific Reports, 2017 Membrane potential controls the response of the M2 muscarinic receptor to its ligands. Membrane hyperpolarization increases response to the full agonist acetylcholine (ACh) while decreasing response to the partial agonist pilocarpine.
I-Shan Chen +2 more
doaj +1 more source
Heart rate responses to a muscarinic agonist in rats with experimentally induced acute and subacute chagasic myocarditis [PDF]
, 2000 Argenis Torres +5 more
openalex +1 more source
State‐dependent regulation of the Kv7.2 channel voltage sensor by QO‐58
British Journal of Pharmacology, EarlyView.Background and Purpose KV7(KCNQ) potassium channels are key modulators of neuronal excitability, and promising targets for development of drugs for epilepsy and pain. We investigated a candidate KV7 drug, QO‐58, which has been previously described but has an unclear mechanism of action.
Richard Kanyo +3 more
wiley +1 more source