Results 91 to 100 of about 1,110,204 (301)

Effect of NF‐κB on Myosin Heavy Chain Content and Muscle Atrophy After Laryngeal Muscle Denervation

World Journal of Otorhinolaryngology-Head and Neck Surgery
Objective To investigate the role of NF‐κB in regulating myosin heavy chain (MyHC) content and muscle atrophy following laryngeal muscle denervation. Methods Rats were divided into five groups: (1) recurrent laryngeal nerve injury (RLNI), (2) RLNI with ...
Jing‐Jing Yang, Rong Hu, Hai‐Zhou Wang, Xue‐Yan Li, Wen Xu   +4 more
doaj   +1 more source

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, EarlyView.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki, Alireza Amindarolzarbi, Tsion Abdi, John Clarke, Michael Hughes, Ami A. Shah, Zsuzsanna H. McMahan   +6 more
wiley   +1 more source

Tail-suspension Induces Altered Expression of GAPDH and ZAKI-4β mRNAs in Rat Hindlimbs : Implication for Disuse Muscle Atrophy

, 2003
2003-12Disuse atrophy of skeletal muscle is a serious complication for a number of bed-ridden patients. We previously demonstrated that unloading of hindlimb muscles by rat tail-suspension for 7 days resulted in disuse atrophy.
Mitsuyama, Hirohito, Seo, Hisao, Miyazaki, Takashi, Kanda, Kazumi, Cao, Xia, Kambe, Fukushi, Ohmori, Sachiko   +6 more
core   +1 more source

Bezafibrate attenuates immobilization-induced muscle atrophy in mice

Scientific Reports
Muscle atrophy due to fragility fractures or frailty worsens not only activity of daily living and healthy life expectancy, but decreases life expectancy.
Satoshi Nakamura, Yuiko Sato, Tami Kobayashi, Akihito Oya, Astuhiro Fujie, Morio Matsumoto, Masaya Nakamura, Arihiko Kanaji, Takeshi Miyamoto   +8 more
doaj   +1 more source

Fabrication Routes for Ionic Conducting Fiber Strain Sensors

Advanced Engineering Materials, EarlyView.
Ionic conducting fiber strain sensors (ICFSs) offer compliant, textile‐integrable sensing. Thus far, the commercialization of ICFSs has been constrained by fiber fabrication routes. This review provides a fabrication‐centric analysis of ICFSs correlating processing strategies with material properties and scalability.
Leo John Kershaw, Zhanhong Yang, Anne Ladegaard Skov, Magdalena Skowyra   +3 more
wiley   +1 more source

Prevention of bone loss during 56 days of strict bed rest by side-alternating resistive vibration exercise [PDF]

, 2010
Bed rest is a recognized model for muscle atrophy and bone loss in space flight and in clinical medicine. We hypothesized that whole body vibration in combination with resistive exercise (RVE) would be an effective countermeasure.
Schubert, Harald, Gast, Ulf, Beller, G., Stegeman, Dick F., Stegeman, D.F., Schiessl, Hans, Mulder, Edwin, de Haan, A., Felsenberg, D., de Haan, Arnold, Armbrecht, G., Buehring, Björn, Haan, A. de, Rittweger, J., Rittweger, Jörn, Buehring, B., Armbrecht, Gabriele, Mulder, E., Schiessl, H., Gast, U., Beller, Gisela, Mulder, Edwin R., Dimeo, Fernando C., Schubert, H., Dimeo, F., Felsenberg, Dieter, Dimeo, Fernando   +26 more
core   +2 more sources

Human skeletal muscle disuse atrophy: effects on muscle protein synthesis, breakdown and insulin resistance- a qualitative review

Frontiers in Physiology, 2016
The ever increasing burden of an ageing population and pandemic of metabolic syndrome worldwide demands further understanding of the modifiable risk factors in reducing disability and morbidity associated with these conditions.
Supreeth S Rudrappa, Daniel Wilkinson, Paul L Greenhaff, Kenneth Smith, Iskandar Idris, Philip James Atherton   +5 more
doaj   +1 more source

Self‐Sintering Ionogel Binder for Flexible, Recyclable, and Healable Printed Giant Magnetoresistive Sensors

Advanced Functional Materials, EarlyView.
ABSTRACT Electronic waste has emerged as a major environmental challenge, driven by the massive consumption and a limited lifetime of modern electronic devices, stimulating the development of sustainable electronics. Here, an all‐biomaterial gelatin‐choline‐citric acid ([Ch][CA]) ionogel is developed as an active binder to realize self‐sintered ...
Lin Guo, Xiaotao Wang, Guannan Mu, Proloy Taran Das, Igor Veremchuk, Conrad Schubert, Aaron D. Cross, Yevhen Zabila, Xuan Peng, Larysa Baraban, Denys Makarov   +10 more
wiley   +1 more source

PGC-1a in muscle links metabolism to inflammation [PDF]

, 2009
1. In higher eukaryotes, metabolism and immunity are tightly coupled. However, whereas in evolutionary terms, a compromised immune response due to undernourishment has been the predominant problem, the inflammatory response to obesity and other life ...
Handschin, C.
core