Results 111 to 120 of about 186,882 (307)

Mechanism of myostatin action during satellite cell activation and muscle wasting.

, 2007
Myostatin, a Transforming Growth Factor-beta (TGF-β) superfamily member, has been well characterised as a negative regulator of muscle growth and development.
McFarlane, Craig Desmond
core  

Multimodal Soft Surgical Robots Enabled by Eco‐Degradable, Sterilizable Polymers and Transient Electronics

Advanced Functional Materials, EarlyView.
A compostable PGS soft surgical robot with interchangeable modules integrates transient Mo tactile and Si thermal sensors for dual feedback. The device preserves its function after clinical‐grade sterilization, demonstrates stable actuation and cardiac tissue grasping with real‐time in vivo pulsatile monitoring, and biodegrades post‐use with soil‐safe, 
Minseong Chae, Kyung‐Sub Kim, Gyeong‐Seok Hwang, Jun‐Seok Shim, Sung‐Woo Kim, Yong‐Wu Kim, Jieun Han, Jae‐Young Bae, Jae‐Hwan Lee, Minjung Chae, Jooik Jeon, Joo‐Hyeon Park, You‐Jung Park, Ju‐Yong Lee, Sung‐Geun Choi, Min‐Ha Oh, Yong‐Joong Shin, Young‐In Ryu, Ji‐Woo Gu, Seong‐Yu Choi, Jeong‐Yun Sun, Jung Keun Hyun, Myoung‐Ryul Ok, Sang Yup Kim, Edyta Wyszkowska, Ju‐Young Kim, Kang‐Sik Lee, Seung‐Kyun Kang   +27 more
wiley   +1 more source

MicroRNA in myogenesis and muscle atrophy [PDF]

Current Opinion in Clinical Nutrition and Metabolic Care, 2013
To understand the impact of microRNA on myogenesis and muscle wasting in order to provide valuable information for clinical investigation.Muscle wasting increases the risk of morbidity/mortality in primary muscle diseases, secondary muscle disorders and elderly population. Muscle mass is controlled by several different signalling pathways. Insulin-like
openaire   +2 more sources

Protective effects of Liuwei dihuang water extracts on diabetic muscle atrophy

, 2019
Background: Liuwei dihuang (LWDH), a widely used traditional Chinese herbal medicine, has been noticed for its potential on the improvement of diabetic complications including diabetic nephropathy and diabetic encephalopathy.
Chang, Fang-Rong, Chang, Wan-Hsuan, Lo, Yi-Ching, Wu, Pao-Chu, Tseng, Yu-Ting, Lin, Chih-Cheng   +5 more
core   +1 more source

Skeletal muscle wasting with disuse atrophy is multi-dimensional: the response and interaction of myonuclei, satellite cells and signaling pathways [PDF]

, 2014
Maintenance of skeletal muscle is essential for health and survival. There are marked losses of skeletal muscle mass as well as strength and physiological function under conditions of low mechanical load, such as space flight, as well as ground based ...
Brooks, Naomi, Myburgh, Kathryn H, Naomi E. Brooks, Kathryn H. Myburgh   +3 more
core   +1 more source

Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review

Advanced Functional Materials, EarlyView.
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera, Chiranjeevi Kanike, Appurva Tiwari, Hongyan Wu, Larry D. Unsworth, Ben Bin Xu, Xuehua Zhang   +6 more
wiley   +1 more source

Phenotype selection reveals coevolution of muscle glycogen and protein and PTEN as a gate keeper for the accretion of muscle mass in adult female mice. [PDF]

, 2012
We have investigated molecular mechanisms for muscle mass accretion in a non-inbred mouse model (DU6P mice) characterized by extreme muscle mass. This extreme muscle mass was developed during 138 generations of phenotype selection for high protein ...
Hammon Harald M., Bidlingmaier, Martin, Bernhard G Baumgartner, Andreas Hoeflich, Zeissler, Anja, Brenig Bertram, Binder Gerhard, Sawitzky, Mandy, Christ Bruno, Binder, Gerhard, Bidlingmaier Martin, Stock Peggy, Metzger, Friedrich, Christ, Bruno, Bertram Brenig, Renne Ulla, Bielohuby Maximilian, Cornelia C Metges, Zeissler Anja, Sawitzky Mandy, Barbara J M Stoehr, Hoeflich Andreas, Metges, Cornelia C., Solvig Görs, Anja Zeissler, Gerhard Binder, Brenig, Bertram, Stoehr, Barbara J. M., Fromm-Dornieden Carolin, Görs, Solvig, Bielohuby, Maximilian, Stock, Peggy, Hammon, Harald M., Hoeflich, Andreas, Stoehr Barbara J. M., Harald M Hammon, Fromm-Dornieden, Carolin, Friedrich Metzger, Langhammer, Martina, Martina Langhammer, Metges Cornelia C., Langhammer Martina, Martin Bidlingmaier, Renne, Ulla, Görs Solvig, Mandy Sawitzky, Peggy Stock, Maximilian Bielohuby, Baumgartner, Bernhard G., Ulla Renne, Carolin Fromm-Dornieden, Baumgartner Bernhard G., Bruno Christ, Metzger Friedrich   +53 more
core   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

Advanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas, Marzia Dulal, Sophia K. Novoselov, Victoria K. Novoselov, Kostya S. Novoselov, Shaila Afroj, Nazmul Karim   +6 more
wiley   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

KLF13 restrains Dll4‐muscular Notch2 axis to improve the muscle atrophy

Journal of Cachexia, Sarcopenia and Muscle
Background Muscle atrophy can cause muscle dysfunction and weakness. Krüppel‐like factor 13 (KLF13), a central regulator of cellular energy metabolism, is highly expressed in skeletal muscles and implicated in the pathogenesis of several diseases.
Shu Yang, Lijiao Xiong, Guangyan Yang, Jiaqing Xiang, Lixing Li, Lin Kang, Zhen Liang   +6 more
doaj   +1 more source