Results 121 to 130 of about 186,882 (307)

Epigenetics of Skeletal Muscle Atrophy

International Journal of Molecular Sciences
Skeletal muscle atrophy, characterized by diminished muscle strength and mass, arises from various causes, including malnutrition, aging, nerve damage, and disease-related secondary atrophy. Aging markedly escalates the prevalence of sarcopenia. Concurrently, the incidence of muscle atrophy significantly rises among patients with chronic ailments such ...
Jiacheng Du, Qian Wu, Eun Ju Bae
openaire   +2 more sources

Prevention of bone loss during 56 days of strict bed rest by side-alternating resistive vibration exercise

, 2010
Bed rest is a recognized model for muscle atrophy and bone loss in space flight and in clinical medicine. We hypothesized that whole body vibration in combination with resistive exercise (RVE) would be an effective countermeasure.
Schubert, Harald, Gast, Ulf, Beller, G., Stegeman, Dick F., Stegeman, D.F., Schiessl, Hans, Mulder, Edwin, de Haan, A., Felsenberg, D., de Haan, Arnold, Armbrecht, G., Buehring, Björn, Haan, A. de, Rittweger, J., Rittweger, Jörn, Buehring, B., Armbrecht, Gabriele, Mulder, E., Schiessl, H., Gast, U., Beller, Gisela, Mulder, Edwin R., Dimeo, Fernando C., Schubert, H., Dimeo, F., Felsenberg, Dieter, Dimeo, Fernando   +26 more
core   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

Advanced Healthcare Materials, EarlyView.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină, Andreea Ioana Dinu, Jana Ghițman   +2 more
wiley   +1 more source

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

Advanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung, Minjun Kim, Da‐Yoon Kim, Min Kyu Kim, Sieun Lee, Yoonhee Jin, Joo H. Kang   +6 more
wiley   +1 more source

Skeletal Muscle Purine Nucleotide Degradation and Atrophy: Cause or Consequence of Increased Uric Acid Production

, 2023
Elevated serum uric acid is a risk factor for mortality in diseases and critical illnesses associated with skeletal muscle atrophy. Uric acid is generated by xanthine oxidoreductase (XOR) and XOR inhibitors can partially attenuate muscle atrophy. Whether
Miller, Spencer Graham, NC DOCKS at East Carolina University   +1 more
core   +1 more source

Irisin regulates the phosphorylation of glucocorticoid receptor Ser212 and Ser234 and mediates glucocorticoid-induced muscle atrophy in mice

Communications Biology
Glucocorticoid-induced skeletal muscle atrophy severely limits the clinical use of glucocorticoids and occurs in various endocrine and metabolic diseases.
Jingjing Yang, Pu Zhang, Yina An, Shuyu Tan, Siqi Sun, Yifan Liu, Lin Zhu, Haidong Wang, Ting Gao, Yanjun Dong   +9 more
doaj   +1 more source

Capsaicin protects against atrophy in human skeletal muscle cells [PDF]

, 2014
Skeletal muscle atrophy occurs in many pathological conditions, e.g. AIDS, cancer, sepsis and starvation, and with increased age. There is currently no effective treatment to prevent or reverse this muscle wasting.
Kortzon, Evelina C
core  

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source

Paradoxical sleep deprivation induces muscle atrophy

, 2012
Introduction: Because paradoxical sleep deprivation (PSD) induces a catabolic hormone profile, we sought to evaluate the morphology of the tibialis anterior (TA) muscle and testosterone and corticosterone levels of paradoxical sleepdeprived rats.Methods:
Marco Túlio de Mello, Antunes, Hanna Karen Moreira [UNIFESP], Sergio Tufik, Murilo Dattilo, Tufik, Sergio [UNIFESP], Kil Sun Lee, Alessandra Medeiros, Mônico-Neto, Marcos [UNIFESP], Marcos Mônico-neto, Medeiros, Alessandra [UNIFESP], Hanna Karen Moreira Antunes, Mello, Marco Tulio de [UNIFESP], Helton de SÁ Souza, Lee, Kil Sun [UNIFESP], Souza, Helton de Sá, Dattilo, Murilo [UNIFESP]   +15 more
core   +1 more source