Results 161 to 170 of about 162,609 (263)

SATB2 Mediates H3K9 Delactylation by Recruiting HDAC3 to Repress LCN2 and Inhibit Lung Tumor Growth and Metastasis

Advanced Science, EarlyView.
This study highlights the capacity for tumor suppressor SATB2 to recruit HDAC3 and catalyze histone H3K9 delactylation, thereby repress transcription of the oncogene LCN2. This novel epigenetic‐metabolic axis inhibits the growth and metastasis of non‐small cell lung cancer, delineating a new mechanistic pathway with potential therapeutic relevance ...
Ting Wen, Lihua Yang, Shuang Cai, Yunxia Liu, Jianan Fan, Peng Wu, Beibei Gao, Xiaoge Xie, Hong Sun, Sida Qin, Qiao Yi Chen   +10 more
wiley   +1 more source

Neuromuscular Mechanisms and Oxidative Stress in Skeletal Muscle Atrophy: Emerging Stem Cell and Gene-Based Therapeutic Strategies. [PDF]

Muscles
Gunasekaran SK, Amzad Khan M, Mirza M, Shanthi Bhupathi S, Abdul Azeeze MST.   +4 more
europepmc   +1 more source

Artificial Piezoelectric Interface Enables Ultrafast Interfacial Ion Kinetic for Highly‐Sensitive Piezoionic Sensors

Advanced Science, EarlyView.
This study proposes a piezoelectric interface modification strategy to amplify the piezoionic effect. The piezoelectric interface generates an intrinsic electric field, which not only drives rapid ion migration but also concentrates polarized ions on the interface. The flexible sensor delivers superior performance, such as a quick response rate, strong
Yanyu Chen, Xingyue Ling, Rizhong Gao, Xiaohong Zhang, Xi Chen, Chao Lu   +5 more
wiley   +1 more source

Gymnemantoside A Ameliorates Steroid-Induced Skeletal Muscle Atrophy via Bridging Glucocorticoid and Insulin Receptor Signalling. [PDF]

J Cachexia Sarcopenia Muscle
Park EJ, Kim HJ, Lee SH, Choi S, Doan TP, Joo KH, An JP, Jung DW, Williams DR, Oh WK.   +9 more
europepmc   +1 more source

Organic Thin‐Film Transistors for Neuromorphic Computing

Advanced Electronic Materials, EarlyView.
Organic thin‐film transistors (OTFTs) are reviewed for neuromorphic computing applications, highlighting their power‐efficient, and biological time‐scale operation. This article surveys OFET and OECT devices, compares them with memristors and CMOS, analyzes how fabrication parameters shape spike‐based metrics, proposes standardized characterization ...
Luke McCarthy, Mohan V. Jacob, Mostafa Rahimi Azghadi   +2 more
wiley   +1 more source

Neural Cues and Genomic Clues: NGS Insights into Neurogenic Sarcopenia and Muscle Atrophy. [PDF]

Int J Mol Sci
Kupriyanova D, Bilyalov A, Filatov N, Brovkin S, Shestakov D, Bodunova N, Gusev O.   +6 more
europepmc   +1 more source

Rethinking Power Solutions for Healthcare Wearables: From Point‐of‐Care and Episodic use to Continuous Monitoring and Therapeutic Platforms

Advanced Energy and Sustainability Research, EarlyView.
This Perspective examines practical power solutions for wearable healthcare systems, highlighting the limits of standard batteries. It categorizes wearables into four domains—point‐of‐care diagnostics, episodic monitoring, continuous long‐term monitoring, and therapeutic platforms—and analyzes their power needs.
Seokheun Choi
wiley   +1 more source

Exercise mitigates IL-27-induced muscle atrophy following myocardial infarction through anti-inflammatory mechanisms. [PDF]

J Transl Med
Li Y, Yin G, Li S, Zheng Q, Jiang Y, Li C, Yang L, Li H, Chen X, Yang P, Sun L.   +10 more
europepmc   +1 more source

Impact of Body Weight Loss During Preoperative Chemoradiotherapy on Prognosis of Patients With Lower Rectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
The present study aimed to investigate the relationship between changes in body weight and composition during chemoradiotherapy, such as the psoas muscle mass index, visceral fat index, and subcutaneous fat index obtained from computed tomography images, and long‐term outcomes in rectal cancer patients.
Shinya Abe, Hiroaki Nozawa, Kazuhito Sasaki, Koji Murono, Shigenobu Emoto, Yuichiro Yokoyama, Yuzo Nagai, Yuzo Harada, Takahide Shinagawa, Soichiro Ishihara   +9 more
wiley   +1 more source

Biglycan Alleviates Age-Related Muscle Atrophy and Hepatocellular Senescence. [PDF]

Int J Mol Sci
Lee DS, Lim JH, Lee YJ.
europepmc   +1 more source