Results 81 to 90 of about 162,609 (263)

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Purpose‐Adaptable Reinforced 3D Hyaluronic‐Acid Based Platform to Study Pathomechanisms of the Central Nervous System

Advanced Healthcare Materials, EarlyView.
Platform system to create biofabricated 3D spinal cord tissue models: Combining high resolution PCL fiber placement, a customized, hyaluronic acid‐based hydrogel, two cell types (spinal cord neurons and astrocytes) together with three distinct laminin isoforms allow the formation of functional cell–cell network interactions.
Nicoletta Murenu, Esra Tuerker, Anna‐Lena Wiessler, Jessica Faber, Ievgenii Liashenko, Jeanette Weigelt, Jörg Tessmar, Paul D. Dalton, Sibylle Jablonka, Mateo S. Andrade Mier, Carmen Villmann, Silvia Budday, Natascha Schaefer   +12 more
wiley   +1 more source

Soft Ionic and Electronic Triboelectric Nanogenerators: Toward Attachable and Implantable Biomedical Applications

Advanced Materials, EarlyView.
This review provides an overview of triboelectric nanogenerator (TENG)–based biomedical applications by classifying studies into electronic and ionic systems across attachable and implantable platforms. It summarizes key material choices, device structures, and working mechanisms that characterize current TENG‐based research, and outlines six future ...
Kyongtae Choi, Jimin Park, Won Jun Song, Soohwan An, Seonggyu Choe, Byeong‐Rak Keum, Min Young Kim, Dae Hee Hwang, Young‐Geun Park, Sung‐Won Kim, Sangyul Baik, Gwang‐Bum Im, Younghoon Lee   +12 more
wiley   +1 more source

Transcriptional Co‐Activator With PDZ Binding Motif (TAZ) Inhibits Dexamethasone‐Induced Muscle Atrophy via mTOR Signalling

Journal of Cachexia, Sarcopenia and Muscle
Background Glucocorticoid therapy has a beneficial effect in several diseases, but chronic treatment has adverse effects, including muscle atrophy, which refers to the gradual decrease in muscle mass, size and strength.
Kyung Min Kim, Ho Taek Oh, Youjin Do, Gi Don Yoo, Woong Heo, Jeekeon Park, Hyejin Yang, Suh Jin Yoon, Mi Ran Byun, Eun Sook Hwang, Jeong‐Ho Hong   +10 more
doaj   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Epigenetics of Skeletal Muscle Atrophy

International Journal of Molecular Sciences
Skeletal muscle atrophy, characterized by diminished muscle strength and mass, arises from various causes, including malnutrition, aging, nerve damage, and disease-related secondary atrophy. Aging markedly escalates the prevalence of sarcopenia. Concurrently, the incidence of muscle atrophy significantly rises among patients with chronic ailments such ...
Jiacheng Du, Qian Wu, Eun Ju Bae
openaire   +2 more sources

Functional Polymers for Ionic Thermoelectrics: Multiscale Design Strategies for Ion Dynamics, Mechanics, and Energy Harvesting

Advanced Materials, EarlyView.
This review highlights the impact of the polymers at the molecular‐, micro‐, and macro‐scale engineering. Particular emphasis is placed on their roles at different scales to provide an in‐depth understanding of performance improvement. In addition, current challenges and potential research approaches are discussed, outlining directions for the future ...
Sungryong Kim, Jin Han Kwon, Juyoung Kang, Hong Chul Moon   +3 more
wiley   +1 more source

N-Acetylcysteine Attenuates Sepsis-Induced Muscle Atrophy by Downregulating Endoplasmic Reticulum Stress

Biomedicines
(1) Background: Sepsis-induced muscle atrophy is characterized by a loss of muscle mass and function which leads to decreased quality of life and worsens the long-term prognosis of patients.
Renyu Chen, Yingfang Zheng, Chenchen Zhou, Hongkai Dai, Yurou Wang, Yun Chu, Jinlong Luo   +6 more
doaj   +1 more source

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

Advanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton, Chris R. Bowen, Hamideh Khanbareh   +2 more
wiley   +1 more source

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source