Results 21 to 30 of about 1,993,181 (312)

Guinea Pig Ciliary Muscle Development [PDF]

open access: yesOptometry and Vision Science, 2014
The purpose of this study was to develop a method for quantifying guinea pig ciliary muscle volume (CMV) and to determine its relationship to age and ocular biometric measurements.Six albino guinea pigs' eyes were collected at each of five ages (n = 30 eyes).
Andrew D, Pucker   +3 more
openaire   +2 more sources

Monitoring muscle fatigue following continuous load changes [PDF]

open access: yes, 2020
Department of Human Factors EngineeringPrevious studies related to monitoring muscle fatigue during dynamic motion have focused on detecting the accumulation of muscle fatigue.
Yoon, Woojin
core  

Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy [PDF]

open access: yes, 2018
Mutations in the gene encoding dystrophin, a protein that maintains muscle integrity and function, cause Duchenne muscular dystrophy (DMD). The deltaE50-MD dog model of DMD harbors a mutation corresponding to a mutational “hotspot” in the human DMD gene.
Amoasii, L   +12 more
core   +2 more sources

miR-324-5p Inhibits C2C12 cell Differentiation and Promotes Intramuscular Lipid Deposition through lncDUM and PM20D1

open access: yesMolecular Therapy: Nucleic Acids, 2020
Skeletal muscle is an important metabolic organ of the body, and impaired skeletal muscle differentiation can result in a wide range of metabolic diseases.
Yihao Liu   +8 more
doaj   +1 more source

Modulation of PGC-1α activity as a treatment for metabolic and muscle-related diseases [PDF]

open access: yes, 2014
Physical inactivity is a predisposing factor for various disease states including obesity, cardiovascular disease, as well as for certain types of cancer. Regular endurance exercise mediates several beneficial effects such as increased energy expenditure
Handschin, Christoph   +1 more
core   +1 more source

Acute and chronic cold exposure differentially affects the browning of porcine white adipose tissue

open access: yesAnimal, 2018
Piglets are characteristically cold intolerant and thus susceptible to high mortality. However, browning of white adipose tissue (WAT) can induce non-shivering thermogenesis as a potential strategy to facilitate the animal’s response to cold.
Y. Gao   +7 more
doaj   +1 more source

Muscle-specific microRNAs in skeletal muscle development

open access: yesDevelopmental Biology, 2016
Proper muscle function constitutes a precondition for good heath and an active lifestyle during an individual's lifespan and any deviations from normal skeletal muscle development and its functions may lead to numerous health conditions including e.g. myopathies and increased mortality.
Horak, Martin   +2 more
openaire   +2 more sources

MicroRNA-222 regulates muscle alternative splicing through Rbm24 during differentiation of skeletal muscle cells [PDF]

open access: yes, 2016
A number of microRNAs have been shown to regulate skeletal muscle development and differentiation. MicroRNA-222 is downregulated during myogenic differentiation and its overexpression leads to alteration of muscle differentiation process and specialized ...
Cappella, Marisa   +7 more
core   +2 more sources

Left dorsolateral prefrontal cortex repetitive transcranial magnetic stimulation reduces the development of long-term muscle pain [PDF]

open access: yes, 2018
The left dorsolateral prefrontal cortex (DLPFC) is involved in the experience and modulation of pain, and may be an important node linking pain and cognition.
De Martino, Enrico   +3 more
core   +3 more sources

Cholesterol-derived glucocorticoids control early fate specification in embryonic stem cells

open access: yesStem Cell Research, 2015
Aside from its role in cell membrane integrity, cholesterol is a key component in steroid hormone production. The vital functions of steroid hormones such as estrogen, testosterone, glucocorticoids (Gcrts) and mineralocorticoids (Mnrts) in perinatal and ...
Joaquim Cabral-Teixeira   +5 more
doaj   +1 more source

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