Results 41 to 50 of about 771,323 (309)

Hox Genes Regulate Muscle Founder Cell Pattern Autonomously and Regulate Morphogenesis Through Motor Neurons [PDF]

open access: yes, 2010
The differentiation of myoblasts to form functional muscle fibers is a consequence of interactions between the mesoderm and ectoderm. The authors examine the role of segment identity in directing these interactions by studying the role of Hox genes in ...
Dutta, Devkanya   +4 more
core   +1 more source

Pask integrates hormonal signaling with histone modification via Wdr5 phosphorylation to drive myogenesis

open access: yeseLife, 2016
PAS domain containing protein kinase (Pask) is an evolutionarily conserved protein kinase implicated in energy homeostasis and metabolic regulation across eukaryotic species.
Chintan K Kikani   +11 more
doaj   +1 more source

Differentiation of multipotent vascular stem cells contributes to vascular diseases. [PDF]

open access: yes, 2012
It is generally accepted that the de-differentiation of smooth muscle cells, from the contractile to the proliferative/synthetic phenotype, has an important role during vascular remodelling and diseases.
Chu, Julia S   +7 more
core   +1 more source

Myogenin controls via AKAP6 non-centrosomal microtubule-organizing center formation at the nuclear envelope

open access: yeseLife, 2021
Non-centrosomal microtubule-organizing centers (MTOCs) are pivotal for the function of multiple cell types, but the processes initiating their formation are unknown. Here, we find that the transcription factor myogenin is required in murine myoblasts for
Robert Becker   +7 more
doaj   +1 more source

A functional motor unit in the culture dish : co-culture of spinal cord explants and muscle cells [PDF]

open access: yes, 2012
Human primary muscle cells cultured aneurally in monolayer rarely contract spontaneously because, in the absence of a nerve component, cell differentiation is limited and motor neuron stimulation is missing(1). These limitations hamper the in vitro study
Arnold, Anne-Sophie   +2 more
core   +1 more source

Klf5 regulates muscle differentiation by directly targeting muscle-specific genes in cooperation with MyoD in mice

open access: yeseLife, 2016
Krüppel-like factor 5 (Klf5) is a zinc-finger transcription factor that controls various biological processes, including cell proliferation and differentiation.
Shinichiro Hayashi   +4 more
doaj   +1 more source

Effects of Protein Hydrolysate from Silkworm (Bombyx mori) pupae on the C2C12 Myogenic Differentiation

open access: yesFoods, 2023
This study investigated the effects and active compounds of silkworm pupae, an edible insect, on C2C12 muscle differentiation. The protein of silkworm pupae was extracted using sonication after defatting with hexane.
Hyeong-Seok Kang   +2 more
doaj   +1 more source

A Poglut1 mutation causes a muscular dystrophy with reduced Notch signaling and satellite cell loss [PDF]

open access: yes, 2016
Skeletal muscle regeneration by muscle satellite cells is a physiological mechanism activated upon muscle damage and regulated by Notch signaling. In a family with autosomal recessive limbgirdle muscular dystrophy, we identified a missense mutation in ...
Cabrera Serrano, Macarena   +5 more
core   +1 more source

Aronia Upregulates Myogenic Differentiation and Augments Muscle Mass and Function Through Muscle Metabolism

open access: yesFrontiers in Nutrition, 2021
Black chokeberry or aronia (the fruit of Aronia melanocarpa) has been reported to having pharmacological activities against metabolic syndrome, such as hypertension, obesity, diabetes, and pro-inflammatory conditions.
Chae-Eun Yun   +14 more
doaj   +1 more source

Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay. [PDF]

open access: yes, 2015
Skeletal muscle satellite cells in their niche are quiescent and upon muscle injury, exit quiescence, proliferate to repair muscle tissue, and self-renew to replenish the satellite cell population.
Blackshear, Perry J   +7 more
core   +2 more sources

Home - About - Disclaimer - Privacy