Results 21 to 30 of about 771,323 (309)
The Role of Embryonic Chick Muscle Cell Culture in the Study of Skeletal Myogenesis
The mechanisms involved in the development of skeletal muscle fibers have been studied in the last 70 years and yet many aspects of this process are still not completely understood.
Manoel L. Costa +3 more
doaj +1 more source
MicroRNA-222 regulates muscle alternative splicing through Rbm24 during differentiation of skeletal muscle cells [PDF]
A number of microRNAs have been shown to regulate skeletal muscle development and differentiation. MicroRNA-222 is downregulated during myogenic differentiation and its overexpression leads to alteration of muscle differentiation process and specialized ...
Cappella, Marisa +7 more
core +2 more sources
HDAC4 regulates skeletal muscle regeneration via soluble factors [PDF]
Skeletal muscle possesses a high ability to regenerate after an insult or in pathological conditions, relying on satellite cells, the skeletal muscle stem cells.
Alessandra Renzini +5 more
core +3 more sources
Myoblast fusion is essential for skeletal muscle development, growth, and regeneration. However, the molecular mechanisms underlying myoblast fusion and differentiation are not fully understood.
Mitsutoshi Kurosaka +3 more
doaj +1 more source
The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration. [PDF]
Metabolic reprogramming is an active regulator of stem cell fate choices, and successful stem cell differentiation in different compartments requires the induction of oxidative phosphorylation.
Cunningham, Thomas J +9 more
core +3 more sources
miRNA mediated downregulation of cyclase-associated protein 1 (CAP1) is required for myoblast fusion
Myoblast fusion is essential for the formation, growth, and regeneration of skeletal muscle, but the molecular mechanisms that govern fusion and myofiber formation remain poorly understood.
Anurag Kumar Singh +4 more
doaj +1 more source
Differential Roles of p300 and PCAF Acetyltransferases in Muscle Differentiation [PDF]
PCAF is a histone acetyltransferase that associates with p300/CBP and competes with E1A for access to them. While exogenous expression of PCAF potentiates both MyoD-directed transcription and myogenic differentiation, PCAF inactivation by anti-PCAF antibody microinjection prevents differentiation.
Pier Lorenzo Puri +10 more
openaire +2 more sources
Obesity is associated with excess body fat accumulation that can cause hyperglycemia and reduce skeletal muscle function and strength, which characterize the development of sarcopenic obesity.
Kippeum Lee +5 more
doaj +1 more source
Muscle Differentiation: A Gene for Slow Muscle? [PDF]
Skeletal muscle comes in two fundamental flavours, slow and fast, which determine physiological performance. Zebrafish screens have provided a handle on the molecular mechanism driving slow muscle formation. The transcriptional repressor Blimp1 has now been shown to be required in embryonic slow muscle precursor cells.
openaire +3 more sources
Meeting the meat: delineating the molecular machinery of muscle development
Muscle, studied mostly with respect to meat production, represents one of the largest protein reservoirs of the body. As gene expression profiling holds credibility to deal with the increasing demand of food from animal sources, excessive loss due to ...
Arif Tasleem Jan +3 more
doaj +1 more source

