Results 11 to 20 of about 771,323 (309)
CBP/p300 and muscle differentiation: no HAT, no muscle [PDF]
The EMBO Journal, 2001 Terminal differentiation of muscle cells follows a precisely orchestrated program of transcriptional regulatory events at the promoters of both muscle-specific and ubiquitous genes. Two distinct families of transcriptional co-activators, GCN5/PCAF and CREB-binding protein (CBP)/p300, are crucial to this process.
A, Polesskaya +9 more
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Muscles, 2023 The skeletal muscle is a highly plastic tissue that shows a remarkable adaptive capacity in response to acute and resistance exercise, and modifies its composition to adapt to use and disuse, a process referred to as muscle plasticity.
Silvia Pomella +9 more
doaj +1 more source
Differential localization of HDAC4 orchestrates muscle differentiation [PDF]
Nucleic Acids Research, 2001 The class II histone deacetylases HDAC4 and HDAC5 interact specifically with the myogenic MEF2 transcription factor and repress its activity. Here we show that HDAC4 is cytoplasmic during myoblast differentiation, but relocates to the nucleus once fusion has occurred. Inappropriate nuclear entry of HDAC4 following overexpression suppresses the myogenic
E A, Miska +5 more
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PCAF Involvement in Lamin A/C-HDAC2 Interplay during the Early Phase of Muscle Differentiation
Cells, 2020 Lamin A/C has been implicated in the epigenetic regulation of muscle gene expression through dynamic interaction with chromatin domains and epigenetic enzymes. We previously showed that lamin A/C interacts with histone deacetylase 2 (HDAC2).
Spartaco Santi +4 more
doaj +1 more source
Adipocyte-Like Differentiation in a Posttreatment Embryonal Rhabdomyosarcoma. [PDF]
, 2015 We describe a 16-year-old boy with rhabdomyosarcoma, consistent with embryonal subtype, of the lower extremity who received systemic neoadjuvant chemotherapy and subsequent excision.
Balitzer, Dana +2 more
core +9 more sources
The differentiation and morphogenesis of craniofacial muscles [PDF]
Developmental Dynamics, 2006 AbstractUnraveling the complex tissue interactions necessary to generate the structural and functional diversity present among craniofacial muscles is challenging. These muscles initiate their development within a mesenchymal population bounded by the brain, pharyngeal endoderm, surface ectoderm, and neural crest cells.
Noden, D M, Francis-West, P
openaire +3 more sources
Effect of Ashwagandha Withanolides on Muscle Cell Differentiation
Biomolecules, 2021 Withania somnifera (Ashwagandha) is used in Indian traditional medicine, Ayurveda, and is believed to have a variety of health-promoting effects. The molecular mechanisms and pathways underlying these effects have not yet been sufficiently explored.
Jia Wang +6 more
doaj +1 more source
Frontiers in Nutrition, 2020 Adequate maternal methyl-donor micronutrient (MET) intake is an important determinant of the organ development and metabolic renovation of offspring. The mechanism involved in skeletal myogenesis and the effect of MET supplementation during pregnancy on ...
Qin He +17 more
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ZNF281/Zfp281 is a target of miR‐1 and counteracts muscle differentiation
Molecular Oncology, 2020 Defects in achieving a fully differentiated state and aberrant expression of genes and microRNAs (miRs) involved in differentiation are common to virtually all tumor types.
Sara Nicolai +11 more
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Methods for Accurate Assessment of Myofiber Maturity During Skeletal Muscle Regeneration
Frontiers in Cell and Developmental Biology, 2020 Adult skeletal muscle has a remarkable ability to regenerate. Regeneration of mature muscle fibers is dependent on muscle stem cells called satellite cells.
Yuki Yoshimoto +4 more
doaj +1 more source