Results 51 to 60 of about 5,165,603 (261)

Soluble RANKL contributes to osteoclast formation in adult mice but not ovariectomy-induced bone loss

Nature Communications, 2018
RANKL is a cytokine produced as a membrane-bound and a secreted protein. Here, using mice lacking soluble RANKL, the authors show that the secreted protein is important for osteoclast function, but not for mammary gland and lymphocyte development.
Jinhu Xiong, Keisha Cawley, Marilina Piemontese, Yuko Fujiwara, Haibo Zhao, Joseph J. Goellner, Charles A. O’Brien   +6 more
doaj   +1 more source

An upper limb musculoskeletal model using bond graphs for rotorcraft-pilot couplings analysis [PDF]

, 2014
Under certain flight conditions, a rotorcraft fuselage motions and vibrations might interact with its pilot voluntary and involuntary actions leading to potentially dangerous dynamic instabilities known as rotorcraft-pilot couplings (RPCs).
GOMAND, Julien, BARRE, Pierre-Jean, TOD, Georges, MALBURET, François   +3 more
core  

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich, Alexis Ogdie, Alisa Stephens Shields, Peter A. Merkel, Shervin Assassi, Elana J. Bernstein, Andreea Bujor, Flavia V. Castelino, Lorinda Chung, Luke B. Evnin, Tracy M. Frech, Jessica K. Gordon, Melissa Griffith, Faye N. Hant, Monica L. Harding, Laura K. Hummers, Dinesh Khanna, Kimberly S. Lakin, Dorota J. Lebiedz‐Odrobina, Yiming Luo, Ashima Makol, Maureen D. Mayes, Zsuzsanna H. McMahan, Jerry Molitor, Duncan F. Moore, Julie Paik, Carrie Richardson, Brian Skaug, Ami A. Shah, Ankoor Shah, Virginia Steen, John M. VanBuren, Elizabeth R. Volkmann, Carleigh Zahn, Nora Sandorfi, for the CONQUER Investigators   +35 more
wiley   +1 more source

An In Vitro Orbital Flow Model to Study Mechanical Loading Effects on Osteoblasts

Biology
Flow induced by an orbital shaker is known to produce shear stress and oscillatory flow, but the utility of this model for studying mechanical loading effects in osteoblasts is not well defined.
Subburaman Mohan, Ritika Surisetty, Chandrasekhar Kesavan   +2 more
doaj   +1 more source

Musculoskeletal biomechanics of the shoulder in functional activities [PDF]

, 2013
The aim of this thesis is to determine shoulder function, during specific functional tasks and relate this to key parameters associated with pathology.
Pandis, Petros
core   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Incidence and prevalence of complaints of the neck and upper extremity in general practice [PDF]

, 2005
OBJECTIVE: To study the incidence and prevalence of neck and upper extremity musculoskeletal complaints in Dutch general practice. METHODS: Data were obtained from the second Dutch national survey of general practice.
Bot, Sandra D.M., Bouter, L. M., Schellevis, F. G., Waal, J.M. van der, Schellevis, F.G., Dekker, J., Van Der Waal, J. M., Bouter, L.M.; id_orcid, Terwee, C. E., Terwee, C.B., Windt, D.A.W.M. van der, Windt - Mens, D.A.W.M. van der, Bouter, L.M., Bot, S.D.M., van der Windt-Mens, D.A.W.M., van der Waal, J.M., Van Der Windt, D. A.W.M.   +16 more
core   +2 more sources

Development and validation of an index of musculoskeletal functional limitations

, 2022
Background: While musculoskeletal problems are leading sources of disability, there has been little research on measuring the number of functionally limiting musculoskeletal problems for use as predictor of outcome in studies of chronic disease.
Wright, Elizabeth, Katz, Jeffrey, Baron, John A, Losina, Elena   +3 more
core   +1 more source

Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective Individuals with systemic lupus erythematosus (SLE) can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the Area Deprivation Index (ADI), and FS in a national SLE sample.
Baljeet Rai, Jessica Fitzpatrick, Jing Li, Eric Roberts, Patricia Katz, Laura Plantinga, Gabriela Schmajuk, Jinoos Yazdany   +7 more
wiley   +1 more source