Results 61 to 70 of about 5,165,603 (261)

Mapping genetic loci that regulate lipid levels in a NZB/B1NJ×RF/J intercross and a combined intercross involving NZB/B1NJ, RF/J, MRL/MpJ, and SJL/J mouse strains

Journal of Lipid Research, 2007
The NZB/B1NJ (NZB) mouse strain exhibits high cholesterol and HDL levels in blood compared with several other strains of mice. To study the genetic regulation of blood lipid levels, we performed a genome-wide linkage analysis in 542 chow-fed F2 female ...
Jon E. Wergedal, Cheryl L. Ackert-Bicknell, Wesley G. Beamer, Subburaman Mohan, David J. Baylink, Apurva K. Srivastava   +5 more
doaj   +1 more source

Health Care Use Among Patients Presenting to Emergency Department for Gout Flares in Ontario, Canada: A Population‐Based Health Systems Analysis

Arthritis Care &Research, EarlyView.
Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.
Timothy S. H. Kwok, Samantha Morais, William K. Silverstein, Clare L. Atzema, Gregory Choy, Priyanka Chandratre, Ping Li, Jessica Widdifield   +7 more
wiley   +1 more source

Cross-species gene modules emerge from a systems biology approach to osteoarthritis

npj Systems Biology and Applications, 2017
Joint degeneration: linking animal and human disease Cartilage, and other tissues in our joints, begins to degenerate with age resulting in pain and reduced mobility; this is termed osteoarthritis (OA). To understand OA better researchers have often used
Alan James Mueller, Elizabeth G. Canty-Laird, Peter D. Clegg, Simon R. Tew   +3 more
doaj   +1 more source

Zoledronic acid prevents pagetic-like lesions and accelerated bone loss in the p62P394L mouse model of Paget's disease

Disease Models & Mechanisms, 2018
Paget's disease of bone (PDB) is an age-related metabolic bone disorder, characterised by focally increased and disorganised bone remodelling initiated by abnormal and hyperactive osteoclasts.
Anna Daroszewska, Lorraine Rose, Nadine Sarsam, Gemma Charlesworth, Amanda Prior, Kenneth Rose, Stuart H. Ralston, Robert J. van ‘t Hof   +7 more
doaj   +1 more source

Lifestyle factors and lumbar disc disease: results of a German multi-center case-control study (EPILIFT) [PDF]

, 2010
Introduction: In the large-scale case-control study EPILIFT, we investigated the dose-response relationship between lifestyle factors (weight, smoking amount, cumulative duration of different sports activities) and lumbar disc disease.
Grifka, Joachim, Bergmann, Annekatrin, Joachim Grifka, Haerting, Johannes, Elsner, Gine, Martina Michaelis, Ulrich Bolm-Audorff, Annekatrin Bergmann, Ellegast, Rolf, Bolm-Audorff, Ulrich, Barbara Schumann, Rolf Ellegast, Gine Elsner, Seidler, Andreas, Ellegast, Rolf Peter, Jäger, Matthias, Schumann, Barbara,, Matthias Jäger, Schumann, Barbara, Andreas Seidler, Michaelis, Martina, Johannes Haerting   +21 more
core   +1 more source

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

Arthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos, William Daniel Soulsby III, Emily von Scheven   +2 more
wiley   +1 more source

Identification of quantitative trait loci that regulate obesity and serum lipid levels in MRL/MpJ × SJL/J inbred mice

Journal of Lipid Research, 2006
The total body fat mass and serum concentration of total cholesterol, HDL cholesterol, and triglyceride (TG) differ between standard diet-fed female inbred mouse strains MRL/MpJ (MRL) and SJL/J (SJL) by 38–120% (P < 0.01).
Apurva K. Srivastava, Subburaman Mohan, Godfred L. Masinde, Hongrun Yu, David J. Baylink   +4 more
doaj   +1 more source

The effectiveness of therapeutic ultrasound for musculoskeletal conditions of the lower limb: a literature review [PDF]

, 2010
Background: Ultrasound is suggested as one of the treatment options available for soft tissue musculoskeletal conditions of the lower limb and to this end, the objective was to review the literature and evaluate the effectiveness of therapeutic ...
Fletcher, Paul, Paul Fletcher, Curran, Mike, Pippa Shanks, Richard Thompson, Michael Curran, Shanks, Pippa, Thompson, Richard   +7 more
core   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

An assessment of undergraduate musculoskeletal training at Medical Schools in South Africa [PDF]

, 2012
Includes abstract.
Dachs, Robert
core   +1 more source