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Massive Mutagenesis®: High-Throughput Combinatorial Site-Directed Mutagenesis
2010Massive Mutagenesis is a proprietary library creation method that enables the fast generation of high-quality genetic libraries. Starting from a single gene on a plasmid and hundreds to thousands of oligonucleotides, a one-step single-strand circular amplification method creates random combinations of several site-directed substitutions, insertions, or
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Cancer risk among World Trade Center rescue and recovery workers: A review
Ca-A Cancer Journal for Clinicians, 2022Paolo Boffetta +2 more
exaly
Splice site m6A methylation prevents binding of U2AF35 to inhibit RNA splicing
Cell, 2021Kamila Delaney +2 more
exaly
Site-Directed Mutagenesis in the Mouse
1993Publisher Summary This chapter presents site-directed mutagenesis in the mouse. The correlation of genotype and phenotype is a central theme in the analysis of development. In the mouse, this type of reverse genetics is constrained not only by the size of the murine genome, which makes positional cloning difficult, but also by the limited ...
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Understanding the inter-site distance effect in single-atom catalysts for oxygen electroreduction
Nature Catalysis, 2021Zhaoyu Jin, Panpan Li, Yan Meng
exaly