Results 41 to 50 of about 136,223 (377)

Polycyclic aromatic hydrocarbons bound to outdoor and indoor airborne particles (PM2.5) and their mutagenicity and carcinogenicity in Silesian kindergartens, Poland

Air quality, atmosphere and health, 2016
Assessment of exposure to polycyclic aromatic hydrocarbons (PAHs) is important due to the widespread presence of PAHs in the environment and their toxicological relevance, especially to susceptible populations such as children and their health.
E. Błaszczyk, W. Rogula-Kozłowska, K. Klejnowski, I. Fulara, Danuta Mielżyńska-Švach   +4 more
semanticscholar   +1 more source

Scientific Opinion on Flavouring Group Evaluation 7, Revision 5 (FGE.07Rev5) : saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched‐chain carboxylic acids from chemical group 5 [PDF]

, 2017
Acknowledgements: The Panel wishes to thank the members of the Working Group on Flavourings: Ulla Beckman Sundh, Leon Brimer, Karl-Heinz Engel, Paul Fowler, Rainer Gürtler, Trine Husøy, Wim Mennes and Gerard Mulder for the preparatory work on this ...
Anastassiadou, Maria, Bolognesi, Claudia, Brimer, Leon, Castle, Laurence, Cravedi, Jean-Pierre, de Fátima Tavares Poças, Maria, EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Engel, Karl-Heinz, Fowler , Paul, Franz, Roland, Grob, Konrad, Gürtler, Rainer, Husøy, Trine, Kärenlampi, Sirpa, Mennes, Wim, Mosesso, Pasquale, Mulder, Gerard, Penninks, André, Rosaria Milana, Maria, Silano, Vittorio, Smith, Andrew, Sundh, Ulla Beckman, Tlustos, Christina, Wölfle , Detlef, Zorn, Holger, Zugravu, Corina-Aurelia   +25 more
core   +3 more sources

Comprehensive In Vitro Safety Assessment of Acorus calamus Rhizome Oil Using OECD-Compliant New Approach Methods: Classification as a GHS Category 1B Sensitiser and Category 2 Irritant

Toxics
Background: Acorus calamus (sweet flag) is widely used in traditional medicine, yet its dermal safety profile remains insufficiently defined under modern regulatory standards.
Karishma R. Desai, Jay R. Ranade, Rajendra M. Nagane, Manish V. Patel, Abhay D. Deshpande, Clive S. Roper, Gireesh Babu Kantli   +6 more
doaj   +1 more source

DNA Oxidation Photoinduced by Norharmane Rhenium(I) Polypyridyl Complexes: Effect of the Bidentate N,N′-Ligands on the Damage Profile [PDF]

, 2018
ReI-polypyridyl complexes have interesting and distinctive photochemical and photosensitizing properties. This work describes the capability to induce (or photoinduce) DNA damage of three ReI-complexes with a naturally occurring alkaloid called ...
Ahmad, Balasingham, Balón, Blasius, Boerner, Boiteux, Bonett, Cao, Coggan, Copeland, Crespy, Daley, de Souza, Dhar, Dong, Epe, Epe, Erkkila, Etienne, Feliz, Fernández-Moreira, Friedman, Gasser, Ghesquière, Gonzalez, Gonzalez, Gonzalez, Gonzalez, Gonzalez, Gonzalez, Hayashi, Häring, Kaplanis, Kastl, Kaulage, Knopf, Krokan, Kumar, Kydonaki, Lakowicz, Lee, Leonidova, Lhiaubet-Vallet, Lo, Maisuls, Maisuls, Maisuls, Mari, Marker, Maron, Martí, McKenzie, McKinley, Müller, Ng, Niesel, Paul, Pohl, Pyle, Ragone, Rasse-Suriani, Ruiz, Ruiz, Ruiz, Salditt, Schatzschneider, Schmidt, Schutte, Schäfer, Shahabadi, Smith, Song, Stemp, Stoeffler, Sun, Taira, Thornton, Vignoni, Wilson, Wolfe, Zeglis, Ziessel, Zobi   +82 more
core   +1 more source

A Review on Mutagenicity Testing for Hazard Classification of Chemicals at Work: Focusing on in vivo Micronucleus Test for Allyl Chloride

Safety and Health at Work, 2015
Chemical mutagenicity is a major hazard that is important to workers' health. Despite the use of large amounts of allyl chloride, the available mutagenicity data for this chemical remains controversial.
Kyung-Taek Rim, Soo-Jin Kim
doaj   +1 more source

Genotoxic and Mutagenic Effects of the Alternaria Mycotoxin Alternariol in Combination with the Process Contaminant Acrylamide

Toxins, 2023
Humans are constantly exposed to mixtures of different xenobiotics through their diet. One emerging concern is the Alternaria mycotoxin alternariol (AOH), which can occur in foods typically contaminated by the process contaminant acrylamide (AA). AA is a
Francesco Crudo, Chenyifan Hong, Elisabeth Varga, Giorgia Del Favero, Doris Marko   +4 more
doaj   +1 more source

Acrolein- and 4-Aminobiphenyl-DNA adducts in human bladder mucosa and tumor tissue and their mutagenicity in human urothelial cells

OncoTarget, 2014
Tobacco smoke (TS) is a major cause of human bladder cancer (BC). Two components in TS, 4-aminobiphenyl (4-ABP) and acrolein, which also are environmental contaminants, can cause bladder tumor in rat models.
Hyun-wook Lee, Hsiang-Tsui Wang, Mao‐wen Weng, Yu Hu, Wei-sheng Chen, David Chou, Yan Liu*, Nicholas M. Donin, W. Huang, H. Lepor, Xue-Ru Wu, Hailin Wang, F. Beland, M. Tang   +13 more
semanticscholar   +1 more source

Adapting the Interrelated Two-way Clustering method for Quantitative Structure-Activity Relationship (QSAR) Modeling of a Diverse Set of Chemical Compounds

, 2013
Interrelated Two-way Clustering (ITC) is an unsupervised clustering method developed to divide samples into two groups in gene expression data obtained through microarrays, selecting important genes simultaneously in the process.
Basak, Subhash C., Grunwald, Gregory D., Majumdar, Subhabrata   +2 more
core   +1 more source

Molnupiravir: From Hope to Epic Fail?

Viruses, 2022
Molnupiravir has been the first oral antiviral authorized for COVID-19 outpatients, reporting extraordinary sales and preserved in vitro efficacy against Omicron sublineages so far.
Daniele Focosi
doaj   +1 more source

His+ reversions Caused in Salmonella typhimurium by different types of ionizing radiation [PDF]

, 1988
The yield of his+ reversions in the Ames Salmonella tester strain TA2638 has been determined for 60Co γ rays, 140 kV X rays, 5.4 keV characteristic X rays, 2.2 MeV protons, 3.1 MeV α particles, and 18 MeV/U Fe ions.
Fitzek, M., Kellerer, Albrecht M., Roos, H., Thomas, W.-H.   +3 more
core   +1 more source