A Single‐Base Mutation in TaWAK3‐B Reduces Plant Height via Cytoskeleton in Bread Wheat
ABSTRACT Introduction of Reduced height (Rht) genes into modern wheat cultivars has resulted in ‘Green Revolution’ that skyrocketed wheat grain yields worldwide since the 1960s. These ‘Green Revolution’ cultivars show shorter plant height, but higher lodging resistance and harvest index.
Naijiao Wang +16 more
wiley +1 more source
<i>In Vitro</i> and <i>In Vivo</i> Safety Evaluation of <i>Streptococcus salivarius</i> eK12, a Genetically Modified Dietary Probiotic Derived from the Oral Probiotic <i>S. salivarius</i> K12. [PDF]
Di Pierro F +15 more
europepmc +1 more source
<i>in vitro</i> evaluation of mutagenic potential in common oral hygiene products. [PDF]
Hegde S +5 more
europepmc +1 more source
An In Vitro and In Vivo Assessment of the Genotoxic Potential of Maizinol (UP165), a Zea mays Leaf Extract. [PDF]
Weston JK, Lynch BS, Akingbasote JA.
europepmc +1 more source
From Hemp Bast to Lyocell Fiber: Sustainable Process Optimization for Lyocell‐Grade Dissolving Pulp
This study presents a sustainable method to produce lyocell‐grade dissolving pulp from Canadian hemp bast fibers. A simplified alkali‐chelation‐bleaching process, free from sulfur and chlorine, yielded high α‐cellulose pulp with low lignin and hemicellulose content. The pulp was successfully spun into continuous hemp‐based lyocell fibers, demonstrating
Md Abu Sayed +8 more
wiley +1 more source
On the Utilization and Characterization of External Biotransformation Systems in <i>In Vitro</i> Toxicology: A Critical Review of the Scientific Literature with Guidance Recommendations. [PDF]
Lungu-Mitea S +7 more
europepmc +1 more source
Structure‐ and Ligand‐Based Discovery of Novel 3‐Chymotrypsin‐Like Protease Nonpeptidomimetic Hits
A multistep virtual screening cascade, integrating shape‐based, ensemble docking, and quantitative structure–activity relationship (QSAR) models, was employed to screen 1.5 million compounds. This funnel identified a novel 3‐chymotrypsin‐like protease (3CLpro) inhibitor, LabMol‐499, which was experimentally validated using a Förster Resonance Energy ...
Sabrina Silva‐Mendonça +14 more
wiley +1 more source
Molecular insights into the bioactivity of H-thiazine compounds against breast cancer cells: a computational study. [PDF]
Mogoane LM +3 more
europepmc +1 more source
Flavonoid Oxime Carbamate Derivatives: Reversal of Multidrug Resistance in Cancer Cells
A set of 23 new flavonoid oxime carbamates was synthesized and evaluated as multidrug resistance (MDR) reversers in ABCB1‐transfected mouse lymphoma cells. All derivatives strongly inhibited P‐glycoprotein (P‐gp) efflux activity in a transport assay, while most selected compounds behaved as ATPase inhibitors. In drug combination assays, they interacted
Filipa Barbosa +5 more
wiley +1 more source
Structure-mutagenicity relationships on quinoline and indole analogues in the Ames test. [PDF]
Kurakami M +7 more
europepmc +1 more source

