Results 11 to 20 of about 1,757,426 (287)
accuMUlate: a mutation caller designed for mutation accumulation experiments [PDF]
Bioinformatics, 2017 Abstract Summary Mutation accumulation (MA) is the most widely used method for directly studying the effects of mutation. By sequencing whole genomes from MA lines, researchers can directly study the rate and molecular spectra of spontaneous mutations and use these results to understand how ...
David J. Winter +5 more
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A comparative study of adaptive mutation operators for metaheuristics [PDF]
, 2009 Genetic algorithms (GAs) are a class of stochastic optimization methods inspired by the principles of natural evolution. Adaptation of strategy parameters and genetic operators has become an important and promising research area in GAs.
Yang, S, Li, C, Korejo, I
core +6 more sources
Consideration of a Liquid Mutation-Accumulation Experiment to Measure Mutation Rates by Successive Serial Dilution [PDF]
Genome Biology and EvolutionCharles Baer +2 more
exaly +2 more sources
Is Natural Population of Candida tropicalis Sexual, Parasexual, and/or Asexual?
Frontiers in Cellular and Infection Microbiology, 2021 Candida tropicalis is one of the most common opportunistic yeast pathogens of humans, especially prevalent in tropical and subtropical regions. This yeast has broad ecological distributions, can be found in both terrestrial and aquatic ecosystems ...
Jianping Xu, Jianping Xu
doaj +1 more source
Stability across the Whole Nuclear Genome in the Presence and Absence of DNA Mismatch Repair
Cells, 2021 We describe the contribution of DNA mismatch repair (MMR) to the stability of the eukaryotic nuclear genome as determined by whole-genome sequencing.
Scott Alexander Lujan, Thomas A. Kunkel
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The Dynamics of Somatic Mutagenesis During Life in Humans
Frontiers in Aging, 2021 From conception to death, human cells accumulate somatic mutations in their genomes. These mutations can contribute to the development of cancer and non-malignant diseases and have also been associated with aging.
Freek Manders +2 more
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Insects, 2022 Despite its substantial costs, sexual reproduction dominates in animals. One popular explanation for the paradox of sex is that asexual reproduction is more likely to accumulate deleterious mutations than sexual reproduction.
Zhi-Chao Yan +3 more
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Mutation Accumulation, Performance, Fitness [PDF]
Integrative and Comparative Biology, 2003 The morphology-performance-fitness paradigm is usually explored by determining whether natural or "phenotypically engineered" variation among individuals in morphology (physiology) or performance covaries with an index of fitness such as survival. Here we study between-line covariation between performance and fitness for 44 lines of flies that had ...
Raymond B, Huey +5 more
openaire +2 more sources
An adaptive mutation operator for particle swarm optimization [PDF]
, 2008 Copyright @ 2008 MICParticle swarm optimization (PSO) is an effcient tool for optimization and search problems. However, it is easy to betrapped into local optima due to its in-formation sharing mechanism.
Yang, S, Li, C, Korejo, I
core +6 more sources
eLife, 2021 The dynamics and diversity of the appearance of genetic variants play an essential role in the evolution of the genome and the shaping of biodiversity.
Abhishek Dutta +2 more
doaj +1 more source