Results 31 to 40 of about 27,474 (197)

DNA repair mechanisms and gametogenesis [PDF]

open access: yes, 2001
In mammals, there is a complex and intriguing relationship between DNA repair and gametogenesis. DNA repair mechanisms are involved not only in the repair of different types of DNA damage in developing germline cells, but ...
Baarends, W.M. (Willy)   +2 more
core   +2 more sources

Prognostic Significance of ARID1A Expression Patterns Varies with Molecular Subtype in Advanced Gastric Cancer

open access: yesGut and Liver, 2023
Background/Aims: AT-rich interactive domain 1A (ARID1A) is frequently mutated in gastric cancer (GC), especially Epstein-Barr virus (EBV)-associated and microsatellite instability high GC.
Jun Yong Kim   +5 more
doaj   +1 more source

MutL homolog 1 expression in thyroid carcinoma and its clinical significance.

open access: yesJournal of Cancer Research and Therapeutics, 2016
OBJECTIVE The aim of this study was to evaluate the MutL homolog 1 (MLH1) protein expression in thyroid cancer patients and its association with clinical pathological characteristics.
Yi Lu   +4 more
semanticscholar   +1 more source

Leucine modulates the IPEC-J2 cell proteome associated with cell proliferation, metabolism and phagocytosis

open access: yesAnimal Nutrition, 2018
Leucine can affect intestinal protein expressions, and improve mucosal immune function. However, little study has been conducted to determine the change of protein component by leucine treatment in intestine epithelial cells.
Xiangbing Mao   +9 more
doaj   +1 more source

Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues [PDF]

open access: yes, 2012
Copyright @ 2012 Bourn et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
Chiranjeevi Sandi   +7 more
core   +2 more sources

Genomic and proteomic evidences unravel the UV-resistome of the poly-extremophile Acinetobacter sp. Ver3 [PDF]

open access: yes, 2015
Ultraviolet radiation can damage biomolecules, with detrimental or even lethal effects for life. Even though lower wavelengths are filtered by the ozone layer, a significant amount of harmful UV-B and UV-A radiation reach Earth?s surface, particularly in
Carolina eBelfiore   +6 more
core   +1 more source

A novel c. 204 Ile68Met germline variant in exon 2 of the mutL homolog 1 gene in a colorectal cancer patient

open access: yesOncology Letters, 2014
Mutations in the mutL homolog 1 (MLH1) gene are frequent in patients with hereditary non-polyposis colorectal cancer (CRC). The MLH1 gene was screened for mutations in patients with sporadic CRC.
P. Vodicka   +8 more
semanticscholar   +1 more source

The G67E mutation in hMLH1 is associated with an unusual presentation of Lynch syndrome [PDF]

open access: yes, 2009
Germline mutations in the mismatch repair (MMR) genes are associated with Lynch syndrome, also known as hereditary non-polyposis colorectal cancer (HNPCC) syndrome.
A Ardern-Jones   +52 more
core   +6 more sources

Comparison of screening strategies for Lynch syndrome in patients with newly diagnosed endometrial cancer: a prospective cohort study in China

open access: yesCancer Communications, 2019
Background The prevalence of Lynch syndrome and screening strategies for this disorder in Chinese patients with endometrial cancer have seldom been investigated.
Xiaopei Chao   +7 more
doaj   +1 more source

Clinical exome performance for reporting secondary genetic findings. [PDF]

open access: yes, 2014
BACKGROUND : Reporting clinically actionable incidental genetic findings in the course of clinical exome testing is recommended by the American College of Medical Genet- ics and Genomics (ACMG).
Clark, P   +6 more
core   +1 more source

Home - About - Disclaimer - Privacy