Results 81 to 90 of about 26,893 (208)

Transcriptome sequencing of Salvia miltiorrhiza after infection by its endophytic fungi and identification of genes related to tanshinone biosynthesis

open access: yesPharmaceutical Biology, 2019
Context: Salvia miltiorrhiza Bunge (Labiatae) is a traditional Chinese herb. Endophytic fungi, which are biotic elicitors, can induce accumulation of secondary metabolites in their host plants.
Yan Jiang   +6 more
doaj   +1 more source

Enhancement of linalool production in Saccharomyces cerevisiae by utilizing isopentenol utilization pathway

open access: yesMicrobial Cell Factories, 2022
Background Linalool is a monoterpenoid, also a vital silvichemical with commercial applications in cosmetics, flavoring ingredients, and medicines. Regulation of mevalonate (MVA) pathway metabolic flux is a common strategy to engineer Saccharomyces ...
Yaoyao Zhang   +3 more
doaj   +1 more source

Deciphering the properties and reaction mechanism of anhydromevalonate phosphate decarboxylase, a prenylated flavin mononucleotide‐dependent enzyme in the archaeal mevalonate pathway

open access: yesThe FEBS Journal, EarlyView.
Characterization of anhydromevalonate phosphate decarboxylase, the UbiD‐family decarboxylase involved in the archaeal mevalonate pathway, was conducted. The enzyme is responsible for the biosynthesis of isoprenoids, such as archaeal membrane lipids, respiratory quinones, and dolichols.
Rino Ishikawa   +9 more
wiley   +1 more source

Carotenoid biosynthesis and overproduction in Corynebacterium glutamicum [PDF]

open access: yes, 2012
Heider S, Peters-Wendisch P, Wendisch VF. Carotenoid biosynthesis and overproduction in Corynebacterium glutamicum. BMC Microbiology. 2012;12(1): 198.Background Corynebacterium glutamicum contains the glycosylated C50 carotenoid decaprenoxanthin as ...
Heider, Sabine   +2 more
core   +2 more sources

Spatially resolved mapping of histones reveals selective neuronal response in Rett syndrome

open access: yesThe FEBS Journal, EarlyView.
Loss of Mecp2 function is associated with Rett syndrome (RTT). MeCP2 regulates chromatin, yet its influence on histone composition and dynamics is unclear. Combining MALDI‐MSI with LCM–LC–MS/MS, we mapped histone proteoforms across the dentate gyrus, cornu ammonis, and cerebellum in two mouse models of RTT.
Frederike Schäfer   +6 more
wiley   +1 more source

Carbocations and the Complex Flavor and Bouquet of Wine: Mechanistic Aspects of Terpene Biosynthesis in Wine Grapes. [PDF]

open access: yes, 2015
Computational chemistry approaches for studying the formation of terpenes/terpenoids in wines are presented, using five particular terpenes/terpenoids (1,8-cineole, α-ylangene, botrydial, rotundone, and the wine lactone), volatile compounds (or their ...
Pemberton, Ryan P   +2 more
core   +2 more sources

Evaluation of the effectiveness and safety of anti‐CGRP monoclonal antibodies in patients with migraine and autoimmune diseases: IMMUNO‐CGRP study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study aimed to evaluate demographic characteristics, treatment effectiveness, and safety outcomes in patients with migraine undergoing anti‐calcitonin gene‐related peptide (CGRP) treatments regarding the presence of autoimmune diseases. Background CGRP has an important role in migraine pathophysiology through neuronal modulation
María Clara García‐Castillo   +37 more
wiley   +1 more source

3-Hydroxy-3-methylglutaryl coenzyme A reductase genes from Glycine max regulate plant growth and isoprenoid biosynthesis

open access: yesScientific Reports, 2023
Isoprenoids, a large kind of plant natural products, are synthesized by the mevalonate (MVA) pathway in the cytoplasm and the 2-C-methyl-d-erythritol 4-phosphate (MEP) pathway in plastids. As one of the rate-limiting enzymes in the MVA pathway of soybean
Shuai Wang   +7 more
doaj   +1 more source

Nursing‐Led Knowledge Translation Strategies to Improve Patient Safety in Hospital Settings: A Scoping Review

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To conduct a scoping review of nurse‐led Knowledge Translation strategies aimed at promoting and enhancing patient safety in hospital settings. Design Scoping review. Methods This review followed the Joanna Briggs Institute methodology and was reported according to PRISMA‐ScR.
Jhenyfer Amanda Ciriaco Canhete   +5 more
wiley   +1 more source

Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus

open access: yesFrontiers in Microbiology, 2018
In this study we addressed the question how a mevalonate (MVA)-auxotrophic Staphylococcus aureusΔmvaS mutant can revert to prototrophy. This mutant couldn’t grow in the absence of MVA.
Sebastian Reichert   +11 more
doaj   +1 more source

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