Results 71 to 80 of about 17,684 (224)
, 2022 The mevalonate (MVA) pathway in eukaryotic organisms produces isoprenoids, sterols, ubiquinone, and dolichols. These molecules are vital for diverse cellular functions, ranging from signaling to membrane integrity, and from post-translational ...
Xue Jiang (411020) +10 more
core +1 more source
Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death
Phytotherapy Research, EarlyView.ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi +6 more
wiley +1 more source
, 2017 Gene sequences putatively involved in the mevalonate (MVA) pathway of P. infestans, or with roles in sterol modification.
Paul Dahlin (107424) +4 more
core +1 more source
Squalene Biosynthesis in Engineered Escherichia Coli
Pharmaceutical Fronts, 2023 Squalene is a natural triterpenoid that is important in medicine, and daily-use chemical and nutraceutical industries. The demand for squalene remains high and constant.
Wei Zhang +3 more
doaj +1 more source
3 Biotech, 2019 In this study, RNA sequencing of several Hevea brasiliensis clones grown in Malaysia with different annual rubber production yields and disease resistance was performed on the Illumina platform. A total of 29,862,548 reads were generated, resulting in 101,269 assembled transcripts that were used as the reference transcripts. A similarity search against
Siti Nurfazilah, Abdul Rahman +3 more
openaire +3 more sources
steel research international, EarlyView.The study presents a dynamic zonal model for hydrogen plasma smelting reduction (HPSR) in direct current arc furnaces, predicting time‐dependent behavior of metal, slag, and off‐gas. The study considers various industrial scenarios to quantify energy demand, hydrogen utilization, degree of reduction, and other operational sensitivities.
Tristan K. Wickham +4 more
wiley +1 more source
Natural Product Communications, 2015 The biosynthetic pathway of terpene trilactones of Ginkgo biloba is unclear. In this present study, suspension cultured cells of G. biloba were used to explore the regulation of the mevalonic acid (MVA) and methylerythritol 4-phosphate (MEP) pathways in ...
Lijia Chen +6 more
doaj +1 more source
Frontiers in Immunology, 2022 A majority of patients with sepsis surviving the first days in intensive care units (ICU) enter a state of immunosuppression contributing to their worsening.
Morgane Crausaz +11 more
doaj +1 more source
p53 regulates the mevalonate pathway in human glioblastoma multiforme.
, 2015 The mevalonate (MVA) pathway is an important metabolic pathway implicated in multiple aspects of tumorigenesis. In this study, we provided evidence that p53 induces the expression of a group of enzymes of the MVA pathway including 3′-hydroxy-3 ...
D'Alessandro, Alba +21 more
core +1 more source
Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery
VIEW, EarlyView.This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf +5 more
wiley +1 more source