Results 51 to 60 of about 1,146,862 (173)

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Baseline survey of indicators of health and wellbeing for the population of Greater Glasgow: final report

, 2000
Core health and wellbeing indicators for Greater Glasgow were developed to monitor what progress was being made towards health targets.
MVA
core   +1 more source

Changing biosynthesis of terpenoid percursors in rice through synthetic biology

Frontiers in Plant Science, 2023
Many highly valued chemicals in the pharmaceutical, biotechnological, cosmetic, and biomedical industries belong to the terpenoid family. Biosynthesis of these chemicals relies on polymerization of Isopentenyl di-phosphate (IPP) and/or dimethylallyl ...
Orio Basallo, Orio Basallo, Lucia Perez, Lucia Perez, Abel Lucido, Abel Lucido, Albert Sorribas, Albert Sorribas, Alberto Marin-Saguino, Alberto Marin-Saguino, Ester Vilaprinyo, Ester Vilaprinyo, Laura Perez-Fons, Alfonso Albacete, Alfonso Albacete, Cristina Martínez-Andújar, Paul D. Fraser, Paul Christou, Paul Christou, Paul Christou, Teresa Capell, Teresa Capell, Rui Alves, Rui Alves   +23 more
doaj   +1 more source

Diverging perspectives on emerging mental health symptoms: Multi‐informant discrepancies and their associated determinants across the transition to adolescence in the Adolescent Brain Cognitive Development Study

JCPP Advances, EarlyView.
Abstract Background The transition from childhood to adolescence is marked by significant developmental, social, and contextual changes that present practical challenges for the measurement of emerging mental health symptoms. This study explores transdiagnostic symptoms across three core dimensions from the Achenbach system of empirically based ...
Matias Martinez, Vijay A. Mittal, Jonathan D. Schaefer, Claudia M. Haase, Katherine S. F. Damme   +4 more
wiley   +1 more source

Comprehensive elucidation of volatile, phenolic, and organic acid profiles in Turkish mallow (Malva sylvestris L.) petal herbal tea: impact of diverse brewing conditions

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Mallow (Malva sylvestris L.) petals are traditionally consumed as herbal tea across the Mediterranean for their soothing and anti‐inflammatory properties; however, scientific characterization of this consumption‐relevant matrix under realistic brewing conditions remains scarce.
Armin Amanpour, Ali Tekin, Ali Adnan Hayaloglu   +2 more
wiley   +1 more source

Mevalonate pathway inhibition reduces bladder cancer metastasis by modulating RhoB protein stability and integrin β1 localization

Communications Biology
The progression and outcome of bladder cancer (BLCA) are critically affected by the propensity of tumor metastasis. Our previous study revealed that activation of the mevalonate (MVA) pathway promoted migration of BLCA cells; however, the exact mechanism
Gang Wang, Tianchen Peng, Liang Chen, Kangping Xiong, Lingao Ju, Kaiyu Qian, Yi Zhang, Yu Xiao, Xinghuan Wang   +8 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Energy Security and Sustainability in the GCC: The Conditional and Contested Role of AI and Digital Infrastructure

Sustainable Development, EarlyView.
ABSTRACT As Gulf Cooperation Council (GCC) economies pursue simultaneous commitments to national AI strategies, renewable energy targets, and Paris Agreement pledges, a key sustainable‐management question remains empirically unresolved: does digital and AI investment genuinely advance energy security and environmental sustainability in hydrocarbon ...
Alanoud Al‐Maadid, Mohamed Sami Ben Ali, Azmat Sher   +2 more
wiley   +1 more source

Squalene Biosynthesis in Engineered Escherichia Coli

Pharmaceutical Fronts, 2023
Squalene is a natural triterpenoid that is important in medicine, and daily-use chemical and nutraceutical industries. The demand for squalene remains high and constant.
Wei Zhang, Yuan Li, Li-Ping Xie, You-Jia Hu   +3 more
doaj   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source