Results 51 to 60 of about 16,944 (177)

Diverging perspectives on emerging mental health symptoms: Multi‐informant discrepancies and their associated determinants across the transition to adolescence in the Adolescent Brain Cognitive Development Study

JCPP Advances, EarlyView.
Abstract Background The transition from childhood to adolescence is marked by significant developmental, social, and contextual changes that present practical challenges for the measurement of emerging mental health symptoms. This study explores transdiagnostic symptoms across three core dimensions from the Achenbach system of empirically based ...
Matias Martinez, Vijay A. Mittal, Jonathan D. Schaefer, Claudia M. Haase, Katherine S. F. Damme   +4 more
wiley   +1 more source

Dynamics of Monoterpene Formation in Spike Lavender Plants

Metabolites, 2017
The metabolic cross-talk between the mevalonate (MVA) and the methylerythritol phosphate (MEP) pathways was analyzed in spike lavender (Lavandula latifolia Med) on the basis of 13CO2-labelling experiments using wildtype and transgenic plants ...
Isabel Mendoza-Poudereux, Erika Kutzner, Claudia Huber, Juan Segura, Isabel Arrillaga, Wolfgang Eisenreich   +5 more
doaj   +1 more source

Comprehensive elucidation of volatile, phenolic, and organic acid profiles in Turkish mallow (Malva sylvestris L.) petal herbal tea: impact of diverse brewing conditions

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Mallow (Malva sylvestris L.) petals are traditionally consumed as herbal tea across the Mediterranean for their soothing and anti‐inflammatory properties; however, scientific characterization of this consumption‐relevant matrix under realistic brewing conditions remains scarce.
Armin Amanpour, Ali Tekin, Ali Adnan Hayaloglu   +2 more
wiley   +1 more source

Mevalonate pathway inhibition reduces bladder cancer metastasis by modulating RhoB protein stability and integrin β1 localization

Communications Biology
The progression and outcome of bladder cancer (BLCA) are critically affected by the propensity of tumor metastasis. Our previous study revealed that activation of the mevalonate (MVA) pathway promoted migration of BLCA cells; however, the exact mechanism
Gang Wang, Tianchen Peng, Liang Chen, Kangping Xiong, Lingao Ju, Kaiyu Qian, Yi Zhang, Yu Xiao, Xinghuan Wang   +8 more
doaj   +1 more source

Fetal Heart Rate at 12 Weeks' Gestation and the Risk of Preterm Birth

Journal of Ultrasound in Medicine, EarlyView.
Objectives To prospectively validate the association between fetal heart rate (FHR) at the 12‐week scan and the risk of preterm birth (PTB), including spontaneous preterm birth (sPTB). Methods This prospective cohort study included 1276 singleton pregnancies undergoing routine first‐trimester screening at 11–13 + 6 weeks' gestation and followed until ...
José Morales‐Roselló, Alicia Soriano‐Payá, Blanca Novillo‐Del Álamo, Alicia Martínez‐Varea   +3 more
wiley   +1 more source

Effective Equilibrium Reaction Zone Modeling of Hydrogen Plasma Smelting Reduction: A Scenario Analysis

steel research international, EarlyView.
The study presents a dynamic zonal model for hydrogen plasma smelting reduction (HPSR) in direct current arc furnaces, predicting time‐dependent behavior of metal, slag, and off‐gas. The study considers various industrial scenarios to quantify energy demand, hydrogen utilization, degree of reduction, and other operational sensitivities.
Tristan K. Wickham, Stephanus P. Du Preez, Dmitri G. Bessarabov, Stephan C. Louw, Ernst L. J. Kleynhans   +4 more
wiley   +1 more source

Squalene Biosynthesis in Engineered Escherichia Coli

Pharmaceutical Fronts, 2023
Squalene is a natural triterpenoid that is important in medicine, and daily-use chemical and nutraceutical industries. The demand for squalene remains high and constant.
Wei Zhang, Yuan Li, Li-Ping Xie, You-Jia Hu   +3 more
doaj   +1 more source

Single-nucleotide polymorphism markers within MVA and MEP pathways among Hevea brasiliensis clones through transcriptomic analysis

3 Biotech, 2019
In this study, RNA sequencing of several Hevea brasiliensis clones grown in Malaysia with different annual rubber production yields and disease resistance was performed on the Illumina platform. A total of 29,862,548 reads were generated, resulting in 101,269 assembled transcripts that were used as the reference transcripts. A similarity search against
Siti Nurfazilah, Abdul Rahman, Mohd Fahmi Abu, Bakar, G Veera, Singham, Ahmad Sofiman, Othman   +3 more
openaire   +3 more sources

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Effect of Enzyme Inhibitors on Terpene Trilactones Biosynthesis and Gene Expression Profiling in Cultured Cells

Natural Product Communications, 2015
The biosynthetic pathway of terpene trilactones of Ginkgo biloba is unclear. In this present study, suspension cultured cells of G. biloba were used to explore the regulation of the mevalonic acid (MVA) and methylerythritol 4-phosphate (MEP) pathways in ...
Lijia Chen, Hui Tong, Mingxuan Wang, Jianhua Zhu, Jiachen Zi, Liyan Song, Rongmin Yu   +6 more
doaj   +1 more source