Results 41 to 50 of about 17,684 (224)

Single-cell analysis reveals divergent responses of human dendritic cells to the MVA vaccine

, 2021
International audienceModified vaccinia Ankara (MVA) is a live, attenuated human smallpox vaccine and a vector for the development of new vaccines against infectious diseases and cancer.
Döring, Marius, Satoh, Takeshi, de Silva, Nilushi,, Conrad, Cécile, Lévy, Yves, Manel, Nicolas, de Azevedo, Kevin, Lahaye, Xavier, Jouve, Mabel, de Silva, Nilushi, S, Gentili, Matteo, Blanco-Rodriguez, Guillermo, Centlivre, Mireille, Nadalin, Francesca   +13 more
core   +1 more source

Optimum conditions for regulating content change of secondary metabolites of Gentiana macrophylla by orthogonal method

Guangxi Zhiwu, 2023
Gentiana macrophylla is a traditional Chinese herbal medicine for treating jaundice, hepatitis, and stomachic and choleretic ailments, and its main secondary metabolites are secoiridiod glycosides represented by gentiopicroside.
Huanhuan FU, Yihan HE, Yangyang YIN, Wei HU, Ye YANG, Zhenggang YUE   +5 more
doaj   +1 more source

Roles for Treg expansion and HMGB1 signaling through the TLR1-2-6 axis in determining the magnitude of the antigen-specific immune response to MVA85A [PDF]

, 2013
© 2013 Matsumiya et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Helen McShane (80704), Pathan, Ansar A, Stylianou, E, Lang, Z, Stephanie A. Harris (429956), Elena Stylianou (292312), Matsumiya, Magali, Griffiths Kristin, Lang Zoe, McShane Helen, Meyer, Joel, Magali Matsumiya, Griffiths, Kristin, Zoe Lang (429954), Lang, Zoe, Ansar A Pathan, Meyer, J, Angela M. Minassian (345365), Magali Matsumiya (429952), Fletcher Helen, Harris, Stephanie A, Rowland Rosalind, Meyer Joel, Kristin Griffiths (429953), Joel Meyer, Harris, SA, McShane, H, Fletcher, Helen, McShane, Helen, Minassian, Angela M, Zoe Lang, Rowland, Rosalind, Matsumiya Magali, Minassian Angela M., Angela M Minassian, Kristin Griffiths, Pathan Ansar A., Joel Meyer (429955), Helen Fletcher, Harris Stephanie A., Rowland, R, Rosalind Rowland, Matsumiya, M, Pathan, AA, Fletcher, H, Minassian, AM, Helen Fletcher (249210), Rosalind Rowland (429957), Helen McShane, Griffiths, K, Elena Stylianou, Stephanie A Harris, Ansar A. Pathan (80697), Stylianou, Elena, Stylianou Elena   +54 more
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Additional file 1 of Synthesis of cembratriene-ol and cembratriene-diol in yeast via the MVA pathway

, 2021
Additional file 1: Figure S1. Diagrams of vector structures. Figure S2. Mass spectra of CBT-ol and GGPP. Figure S3. Yeast growth and cembranoid production by shake-flask cultivation. Table S1. Codon-optimized sequences of CBTS1 and CYP450. Table S2. Primers for vector construction. Table S3. Gradient mobile phase for UPLC assay.
Zhang, Yu, Bian, Shiquan, Liu, Xiaofeng, Fang, Ning, Wang, Chunkai, Liu, Yanhua, Du, Yongmei, Timko, Michael P., Zhang, Zhongfeng, Zhang, Hongbo   +9 more
openaire   +2 more sources

The MVA pathway bypasses fosmidomycin toxicity in PfMev parasites.

, 2020
A) Diagram of the parasite cell showing that the endogenous MEP pathway is localized with the apicoplast organelle of the parasite, with IPP and DMAPP presumably being exported out of the organelle.
Hans B. Liu (8452467), Anders Wallqvist (43485), Shivendra G. Tewari (8452482), Amanda Dziedzic (2549350), Russell P. Swift (8452464), Sean T. Prigge (370088), Namandje N. Bumpus (8452479), Krithika Rajaram (3350864), Hugo Jhun (8153199), Krista A. Matthews (8452476), Anne E. Jedlicka (8452470), Aleah D. Roberts (8452473)   +11 more
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The Mevalonate Pathway, a Metabolic Target in Cancer Therapy

Frontiers in Oncology, 2021
A hallmark of cancer cells includes a metabolic reprograming that provides energy, the essential building blocks, and signaling required to maintain survival, rapid growth, metastasis, and drug resistance of many cancers.
Borja Guerra, Carlota Recio, Haidée Aranda-Tavío, Miguel Guerra-Rodríguez, José M. García-Castellano, Leandro Fernández-Pérez   +5 more
doaj   +1 more source

Image_7_The Mevalonate Pathway Is Important for Growth, Spore Production, and the Virulence of Phytophthora sojae.TIF

, 2022
The mevalonate (MVA) pathway in eukaryotic organisms produces isoprenoids, sterols, ubiquinone, and dolichols. These molecules are vital for diverse cellular functions, ranging from signaling to membrane integrity, and from post-translational ...
Xue Jiang (411020), Huiying Sun (338156), Weiqi Yan (5793062), Xin Zhang (35492), Wenwu Ye (154887), Yuanhua Wu (5237519), Qifeng Huang (11866166), Yue Liang (2294437), Francine Govers (52155), Zhichao Zhang (530603), Xinyu Yang (197010)   +10 more
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Table_1_The Mevalonate Pathway Is Important for Growth, Spore Production, and the Virulence of Phytophthora sojae.XLSX

, 2022
The mevalonate (MVA) pathway in eukaryotic organisms produces isoprenoids, sterols, ubiquinone, and dolichols. These molecules are vital for diverse cellular functions, ranging from signaling to membrane integrity, and from post-translational ...
Xue Jiang (411020), Huiying Sun (338156), Weiqi Yan (5793062), Xin Zhang (35492), Wenwu Ye (154887), Yuanhua Wu (5237519), Qifeng Huang (11866166), Yue Liang (2294437), Francine Govers (52155), Zhichao Zhang (530603), Xinyu Yang (197010)   +10 more
core   +1 more source

Image_2_The Mevalonate Pathway Is Important for Growth, Spore Production, and the Virulence of Phytophthora sojae.TIF

, 2022
The mevalonate (MVA) pathway in eukaryotic organisms produces isoprenoids, sterols, ubiquinone, and dolichols. These molecules are vital for diverse cellular functions, ranging from signaling to membrane integrity, and from post-translational ...
Xue Jiang (411020), Huiying Sun (338156), Weiqi Yan (5793062), Xin Zhang (35492), Wenwu Ye (154887), Yuanhua Wu (5237519), Qifeng Huang (11866166), Yue Liang (2294437), Francine Govers (52155), Zhichao Zhang (530603), Xinyu Yang (197010)   +10 more
core   +1 more source

Image_5_The Mevalonate Pathway Is Important for Growth, Spore Production, and the Virulence of Phytophthora sojae.TIF

, 2022
The mevalonate (MVA) pathway in eukaryotic organisms produces isoprenoids, sterols, ubiquinone, and dolichols. These molecules are vital for diverse cellular functions, ranging from signaling to membrane integrity, and from post-translational ...
Xue Jiang (411020), Huiying Sun (338156), Weiqi Yan (5793062), Xin Zhang (35492), Wenwu Ye (154887), Yuanhua Wu (5237519), Qifeng Huang (11866166), Yue Liang (2294437), Francine Govers (52155), Zhichao Zhang (530603), Xinyu Yang (197010)   +10 more
core   +1 more source