Results 61 to 70 of about 16,944 (177)

An Overview of High‐Temperature Superconducting Cables in DC Systems: Unlocking Potential for High‐Voltage DC Networks

open access: yesHigh Voltage, EarlyView.
ABSTRACT This paper provides an overview of high‐temperature superconducting (HTS) cables in DC systems, with a focus on their deployment in high‐voltage DC (HVDC) networks. The assessment of HTS cable properties—such as extremely low electrical resistance, high current‐carrying capacity and a compact geometry—and their comparison with those of ...
Mohammad Hossein Mousavi   +2 more
wiley   +1 more source

Transcriptomic profiling reveals MEP pathway contributing to ginsenoside biosynthesis in Panax ginseng

open access: yesBMC Genomics, 2019
Background Panax ginseng C. A. Mey is one of famous medicinal herb plant species. Its major bioactive compounds are various ginsenosides in roots and rhizomes.
Le Xue   +6 more
doaj   +1 more source

Additional file 1 of Optimizing the downstream MVA pathway using a combination optimization strategy to increase lycopene yield in Escherichia coli

open access: yes, 2022
Additional file 1: Table S1. Primers used in this study. Figure S1. Ten colonies were randomly picked and analyzed by colony PCR to determine ratio of successfully assembled pHM-library, pMM-library, and pLM-library. M marker.
Cheng, Tao   +3 more
openaire   +1 more source

Minocycline and bone marrow–derived mononuclear cells as potential therapeutics for hereditary retinal degenerations

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To assess in Royal College of Surgeons (RCS) rats if the combination of two previously documented neuroprotective strategies: minocycline administration and bone marrow–derived mononuclear cells (BM‐MNCs) intravitreal transplantation, offers enhanced neuroprotection compared with each treatment alone.
Alba Videla‐Ristol   +6 more
wiley   +1 more source

miR-612 Enhances RSL3-Induced Ferroptosis of Hepatocellular Carcinoma Cells via Mevalonate Pathway

open access: yesJournal of Hepatocellular Carcinoma, 2023
Kailin Xing,1,* Xinyu Bian,2,* Dongmin Shi,3,* Shuangshuang Dong,1 Hongxin Zhou,1 Shuxiu Xiao,4 Jinjin Bai,4 Weizhong Wu1,4 1Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion ...
Xing K   +7 more
doaj  

Improving Adaptive and Memory Immune Responses of an HIV/AIDS Vaccine Candidate MVA-B by Deletion of Vaccinia Virus Genes (C6L and K7R) Blocking Interferon Signaling Pathways. [PDF]

open access: yesPLoS ONE, 2013
Poxvirus vector Modified Vaccinia Virus Ankara (MVA) expressing HIV-1 Env, Gag, Pol and Nef antigens from clade B (termed MVA-B) is a promising HIV/AIDS vaccine candidate, as confirmed from results obtained in a prophylactic phase I clinical trial in ...
Juan García-Arriaza   +4 more
doaj   +1 more source

A luminal non‐coding RNA‐based genomic classifier confirms favourable outcomes in patients with clinically organ‐confined bladder cancer treated with radical cystectomy

open access: yesBJU International, Volume 135, Issue 4, Page 648-656, April 2025.
Objective To further evaluate a genomic classifier (GC) in a cohort of patients undergoing radical cystectomy (RC), as long non‐coding RNA (lncRNA)‐based genomic profiling has suggested utility in identifying a distinct tumour subgroup corresponding to a favourable prognosis in patients with bladder cancer.
Joep J. de Jong   +14 more
wiley   +1 more source

Enhancement of linalool production in Saccharomyces cerevisiae by utilizing isopentenol utilization pathway

open access: yesMicrobial Cell Factories, 2022
Background Linalool is a monoterpenoid, also a vital silvichemical with commercial applications in cosmetics, flavoring ingredients, and medicines. Regulation of mevalonate (MVA) pathway metabolic flux is a common strategy to engineer Saccharomyces ...
Yaoyao Zhang   +3 more
doaj   +1 more source

Spatially resolved mapping of histones reveals selective neuronal response in Rett syndrome

open access: yesThe FEBS Journal, EarlyView.
Loss of Mecp2 function is associated with Rett syndrome (RTT). MeCP2 regulates chromatin, yet its influence on histone composition and dynamics is unclear. Combining MALDI‐MSI with LCM–LC–MS/MS, we mapped histone proteoforms across the dentate gyrus, cornu ammonis, and cerebellum in two mouse models of RTT.
Frederike Schäfer   +6 more
wiley   +1 more source

Updates and controversies in contemporary grading of clear cell renal cell carcinoma and papillary renal cell carcinoma

open access: yesHistopathology, EarlyView.
New concepts, innovations and some issues have emerged since the adoption a decade ago of WHO/ISUP grading for CCRCC and PRCC. Continued use of the WHO/ISUP grading for CCRCC and PRCC has been upheld by newer studies, and practice guidance for some of the grading issues, where data are available, is provided.
Gladell P. Paner   +4 more
wiley   +1 more source

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