Results 61 to 70 of about 1,146,862 (173)

Effect of Enzyme Inhibitors on Terpene Trilactones Biosynthesis and Gene Expression Profiling in Cultured Cells

Natural Product Communications, 2015
The biosynthetic pathway of terpene trilactones of Ginkgo biloba is unclear. In this present study, suspension cultured cells of G. biloba were used to explore the regulation of the mevalonic acid (MVA) and methylerythritol 4-phosphate (MEP) pathways in ...
Lijia Chen, Hui Tong, Mingxuan Wang, Jianhua Zhu, Jiachen Zi, Liyan Song, Rongmin Yu   +6 more
doaj   +1 more source

Dynamics of Monoterpene Formation in Spike Lavender Plants

Metabolites, 2017
The metabolic cross-talk between the mevalonate (MVA) and the methylerythritol phosphate (MEP) pathways was analyzed in spike lavender (Lavandula latifolia Med) on the basis of 13CO2-labelling experiments using wildtype and transgenic plants ...
Isabel Mendoza-Poudereux, Erika Kutzner, Claudia Huber, Juan Segura, Isabel Arrillaga, Wolfgang Eisenreich   +5 more
doaj   +1 more source

An Overview of High‐Temperature Superconducting Cables in DC Systems: Unlocking Potential for High‐Voltage DC Networks

High Voltage, EarlyView.
ABSTRACT This paper provides an overview of high‐temperature superconducting (HTS) cables in DC systems, with a focus on their deployment in high‐voltage DC (HVDC) networks. The assessment of HTS cable properties—such as extremely low electrical resistance, high current‐carrying capacity and a compact geometry—and their comparison with those of ...
Mohammad Hossein Mousavi, Hassan Moradi, Kumars Rouzbehi   +2 more
wiley   +1 more source

The MVA pathway bypasses fosmidomycin toxicity in PfMev parasites.

, 2020
A) Diagram of the parasite cell showing that the endogenous MEP pathway is localized with the apicoplast organelle of the parasite, with IPP and DMAPP presumably being exported out of the organelle.
Hans B. Liu (8452467), Anders Wallqvist (43485), Shivendra G. Tewari (8452482), Amanda Dziedzic (2549350), Russell P. Swift (8452464), Sean T. Prigge (370088), Namandje N. Bumpus (8452479), Krithika Rajaram (3350864), Hugo Jhun (8153199), Krista A. Matthews (8452476), Anne E. Jedlicka (8452470), Aleah D. Roberts (8452473)   +11 more
core   +1 more source

Improved adjuvanting of seasonal influenza vaccines: Pre-clinical studies of MVA-NP+M1 co-administration with inactivated influenza vaccine. [PDF]

, 2013
Licensed seasonal influenza vaccines induce antibody responses against influenza hemagglutinin that are limited in their ability to protect against different strains of influenza.
Gilbert, SC, Temperton, Nigel J., Charleston, Bryan, Molesti, E, Sarah C. Gilbert, Butter, Colin, Massimiliano Baratelli, Lambe, Teresa, Boyd, A, Mullarkey, CE, Charleston, B, Caitlin E. Mullarkey, Eleonora Molesti, Gilbert, Sarah, van Laarhoven, Arjan, Veronica Carr, B, van Laarhoven, A, Eric A. Lefevre, Molesti, Eleonora, Amy Boyd, Colin Butter, Mullarkey, Caitlin E, Gilbert, Sarah C, Lefevre, EA, B. Veronica Carr, Arjan van Laarhoven, Nigel J. Temperton, Lambe, T, Baratelli, M, Carr, B Veronica, Baratelli, Massimiliano, Lefevre, Eric A, Boyd, Amy, Temperton, NJ, Butter, C, Teresa Lambe, Bryan Charleston   +36 more
core   +1 more source

miR-612 Enhances RSL3-Induced Ferroptosis of Hepatocellular Carcinoma Cells via Mevalonate Pathway

Journal of Hepatocellular Carcinoma, 2023
Kailin Xing,1,* Xinyu Bian,2,* Dongmin Shi,3,* Shuangshuang Dong,1 Hongxin Zhou,1 Shuxiu Xiao,4 Jinjin Bai,4 Weizhong Wu1,4 1Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion ...
Xing K, Bian X, Shi D, Dong S, Zhou H, Xiao S, Bai J, Wu W   +7 more
doaj  

Transcriptomic profiling reveals MEP pathway contributing to ginsenoside biosynthesis in Panax ginseng

BMC Genomics, 2019
Background Panax ginseng C. A. Mey is one of famous medicinal herb plant species. Its major bioactive compounds are various ginsenosides in roots and rhizomes.
Le Xue, Zilong He, Xiaochun Bi, Wei Xu, Ting Wei, Shuangxiu Wu, Songnian Hu   +6 more
doaj   +1 more source

Unraveling Suicidal Ideation and Behaviors in a Global Cohort of Individuals at Clinical High‐Risk for Psychosis: Multivariable Correlates and Subthreshold Psychotic Symptoms

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Suicidal ideation and behaviors (SIB) are common among individuals at clinical high risk for psychosis (CHR‐P), but their relationship with the overall clinical profile remains unclear. This study aimed to identify sociodemographic/clinical factors associated with SIB in CHR‐P individuals and to examine whether subthreshold ...
Stefano Damiani, Marika Orlandi, Umberto Provenzani, Elisa Bortolin, Margherita Rovida, Riccardo Stefanelli, Jean Addington, Luis Alameda, Celso Arango, Nicholas J. K. Breitborde, Matthew R. Broome, Kristin S. Cadenhead, Monica E. Calkins, Ricardo E. Carrion, Rolando I. Castillo‐Passi, Eric Yu Hai Chen, Jimmy Choi, Philippe Conus, Barbara A. Cornblatt, Covadonga M. Diaz‐Caneja, Lauren M. Ellman, Abigayle Fogarty, Pablo A. Gaspar, Carla Gerber, Louise Birkedal Glenthøj, Leslie E. Horton, Christy Lai Ming Hui, Joseph Kambeitz, Lana Kambeitz‐Ilankovic, Matcheri S. Keshavan, Minah Kim, Sung‐Wan Kim, Nikolaos Koutsouleris, Zsuliet Kristof, Jun Soo Kwon, Kerstin Langbein, Daniel Mamah, Daniel H. Mathalon, Vijay A. Mittal, Josh Nguyen, Merete Nordentoft, Godfrey D. Pearlson, Nora Penzel, Jesus Perez, Diana O. Perkins, Albert R. Powers III, Jack Rogers, Fred W. Sabb, Jason Schiffman, Jai L. Shah, Steven M. Silverstein, Stefan Smesny, William S. Stone, Gregory P. Strauss, Judy L. Thompson, Rachel Upthegrove, Swapna Verma, Cassandra Wannan, Jijun Wang, Heather Wastler, Daniel H. Wolf, Tianhong Zhang, Sylvain Bouix, Cheryl M. Corcoran, Tina Kapur, Ofer Pasternak, Carrie E. Bearden, Rene S. Kahn, John M. Kane, Patrick D. McGorry, Barnaby Nelson, Martha E. Shenton, Scott W. Woods, Paolo Fusar‐Poli   +73 more
wiley   +1 more source

p53 regulates Mevalonate Metabolic pathway

, 2014
2012-2013The mevalonate pathway is an important metabolic pathway implicated in multiple aspects of tumorigenesis. In this study, I provided evidences about genetic and pharmacologic perturbation of p53, which directly influenced expression of mevalonate
D'Alessandro, Alba
core   +1 more source

Improving Adaptive and Memory Immune Responses of an HIV/AIDS Vaccine Candidate MVA-B by Deletion of Vaccinia Virus Genes (C6L and K7R) Blocking Interferon Signaling Pathways. [PDF]

PLoS ONE, 2013
Poxvirus vector Modified Vaccinia Virus Ankara (MVA) expressing HIV-1 Env, Gag, Pol and Nef antigens from clade B (termed MVA-B) is a promising HIV/AIDS vaccine candidate, as confirmed from results obtained in a prophylactic phase I clinical trial in ...
Juan García-Arriaza, Pilar Arnáez, Carmen E Gómez, Carlos Óscar S Sorzano, Mariano Esteban   +4 more
doaj   +1 more source