Results 61 to 70 of about 26,893 (208)

The Identification of β-Ocimene Biosynthetic Pathway Through Mevalonate Acid (MVA) and 1-Deoxy-D-Xylulose 5-Phosphate (DXP) Pathways Using Crude Enzyme Extracts in Indonesian Bay Leaf/Salam Leaf (Syzygium polyanthum)

Tropical Life Sciences Research, 2022
Salam leaf has a β-ocimene as a key volatile compound that gives a fresh aroma to the food when the salam leaves are involved in the cooking process. As a secondary metabolic product, enzymatic biosynthesis as the early stage of β-ocimene is a factor that needs to be known.
Pratama, Bima Putra, Pranoto, Yudi, Supriyadi,, Swasono, Respati Tri   +3 more
openaire   +2 more sources

Dynamics of Monoterpene Formation in Spike Lavender Plants

Metabolites, 2017
The metabolic cross-talk between the mevalonate (MVA) and the methylerythritol phosphate (MEP) pathways was analyzed in spike lavender (Lavandula latifolia Med) on the basis of 13CO2-labelling experiments using wildtype and transgenic plants ...
Isabel Mendoza-Poudereux, Erika Kutzner, Claudia Huber, Juan Segura, Isabel Arrillaga, Wolfgang Eisenreich   +5 more
doaj   +1 more source

The bHLH transcription factors TSAR1 and TSAR2 regulate triterpene saponin biosynthesis in Medicago truncatula [PDF]

, 2015
Plants respond to stresses by producing a broad spectrum of bioactive specialized metabolites. Hormonal elicitors, such as jasmonates, trigger a complex signaling circuit leading to the concerted activation of specific metabolic pathways.
Goossens, Alain, Lopez-Vidriero, Irene, Manuel Franco-Zorrilla, José, Mertens, Jan, Pollier, Jacob, Vanden Bossche, Robin   +5 more
core   +2 more sources

Disease Site‐Specific Outcomes in p16‐Positive Non‐Oropharyngeal Mucosal Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Objectives To report disease‐free survival (DFS) in p16‐positive non‐oropharyngeal head‐and‐neck squamous‐cell carcinoma (HNSCC). Methods Curatively‐treated non‐oropharyngeal HNSCC (2009–2021) were reviewed. DFS was compared among p16‐positive, p16‐negative, and p16‐untested cases for the overall cohort and by disease site.
Revadhi C. Chelvarajah, Lessandra Y. S. Chee, Jie Su, Brian O'Sullivan, Christopher M. K. L. Yao, Enrique Sanz‐Garcia, Stephen M. Smith, Ilan Weinreb, Scott Bratman, B. C. John Cho, Ezra Hahn, Andrew Hope, Ali Hosni, John Kim, Andrew McPartlin, Nauman Malik, Chiaojung Jillian Tsai, John de Almeida, Anna Spreafico, Li Tong, Shao Hui Huang, John N Waldron   +21 more
wiley   +1 more source

The putative mevalonate diphosphate decarboxylase from Picrophilus torridus is in reality a mevalonate-3-kinase with high potential for bioproduction of isobutene [PDF]

, 2015
Mevalonate diphosphate decarboxylase (MVD) is an ATP-dependent enzyme that catalyzes the phosphorylation/decarboxylation of (R)-mevalonate-5-diphosphate to isopentenyl pyrophosphate in the mevalonate (MVA) pathway.MVD is a key enzyme in engineered ...
A. M. Spormann, Gill Stephens, Global Bioenergies, Graham Eastham, Luca Rossoni, Organization for Economic Cooperation and Development, Peter Licence, Stephen J. Hall, UniProt Consortium   +8 more
core   +3 more sources

Integration of contraception provision in emergency obstetric and neonatal care: A scoping review

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Emergency obstetric and neonatal care (EmONC) provides a framework to assess the capacity of health systems and mitigate maternal mortality. Given the high unmet need for contraception, integrating contraception provision and EmONC services could improve maternal and newborn health outcomes.
Mikaela R. Koch, Asha Kasliwal, Nasser Elkholy, Kidist Gizachew, Azra Ashan, Anita Makins, Helena Kallner, Sian Mosedale, Aparna Sridhar   +8 more
wiley   +1 more source

Coordinated carbon metabolite flux between the methyl erythritol phosphate (MEP) and the mevalonate (MVA) pathway regulates the withanolide biosynthesis in Withania somnifera (L.) Dunal

Discover Plants
Withanolides are bioactive triterpenoids that require isoprene units viz., isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) as precursor molecule for their biosynthesis, mediated via two independent routes, the plastidial methyl ...
Prince Choyal, Virendra Singh Rana, Maharishi Tomar, Kalidindi Usha, Bhupinder Singh   +4 more
doaj   +1 more source

Metabolic origins and transport of vitamin e biosynthetic precursors [PDF]

, 2017
Tocochromanols are organic compounds mostly produced by photosynthetic organisms that exhibit vitamin E activity in animals. They result from the condensation of homogentisate with four different polyprenyl side chains derived all from geranylgeranyl ...
Mène-Saffrané, Laurent, Pellaud, Sébastien   +1 more
core   +2 more sources

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Squalene Biosynthesis in Engineered Escherichia Coli

Pharmaceutical Fronts, 2023
Squalene is a natural triterpenoid that is important in medicine, and daily-use chemical and nutraceutical industries. The demand for squalene remains high and constant.
Wei Zhang, Yuan Li, Li-Ping Xie, You-Jia Hu   +3 more
doaj   +1 more source