Results 91 to 100 of about 1,146,862 (173)
Elamipretide Rejuvenates Oocyte Quality and Restores Female Fertility During Reproductive Aging
We reported a novel peptide therapy showing that elamipretide restores the quality of aged oocytes for fertility by coordinately boosting oocyte nuclear and cytoplasmic maturation via activation of the VEGF signaling pathway. ABSTRACT Aging represents a major contributor to the deterioration of female fertility, with oocyte quality being the central ...
Hao‐Lin Zhang +12 more
wiley +1 more source
Heterologous (Ad26-Ad35, Ad26-MVA or MVA-Ad26) prime at week 0 and boost at week 8 with a trivalent vaccine, or empty Ad26-Ad35 vectors, at the doses indicated. One group received a heterologous Ad26-Ad35 prime at week 4 and boost at week 8 of monovalent
Hanneke Schuitemaker (85702) +20 more
core +1 more source
Spatially resolved mapping of histones reveals selective neuronal response in Rett syndrome
Rett syndrome (RTT) is a severe neurological disorder caused by loss‐of‐function mutations in the X‐linked MECP2 gene that causes profound life‐long neurological dysfunction. MeCP2 regulates chromatin, yet its influence on histone composition and dynamics is unclear.
Frederike Schäfer +6 more
wiley +1 more source
Single-cell analysis reveals divergent responses of human dendritic cells to the MVA vaccine
International audienceModified vaccinia Ankara (MVA) is a live, attenuated human smallpox vaccine and a vector for the development of new vaccines against infectious diseases and cancer.
Döring, Marius +13 more
core +1 more source
ABSTRACT Universities are under increasing pressure to convert strategic priorities into participatory and sustained internal change. This study examines a 5‐year president‐led challenge program at a private Latin American university as a governance mechanism for internal innovation.
Andrés Muñoz‐Villamizar +1 more
wiley +1 more source
Correction to: Optimizing the downstream MVA pathway using a combination optimization strategy to increase lycopene yield in Escherichia coli. [PDF]
Cheng T, Wang L, Sun C, Xie C.
europepmc +1 more source
New concepts, innovations and some issues have emerged since the adoption a decade ago of WHO/ISUP grading for CCRCC and PRCC. Continued use of the WHO/ISUP grading for CCRCC and PRCC has been upheld by newer studies, and practice guidance for some of the grading issues, where data are available, is provided.
Gladell P. Paner +4 more
wiley +1 more source
Understanding and classifying the raw water transfer invasion pathway [PDF]
Raw Water Transfer (RWT) schemes move large volumes of freshwater between separate waterbodies to supply water as a specific commodity. Water is translocated by complex purpose-built networks of pipelines, tunnels and water supply canals.
Waine, Ava +2 more
core +1 more source
Evolution‐Inspired Engineering of Diterpene Biosynthesis via Chloroplast Genome Modification
ABSTRACT Terpenes constitute the largest and most structurally diverse class of plant secondary metabolites, with critical roles in plant‐environment interactions and broad industrial applications. Although nuclear genome engineering of terpene pathways has been extensively explored, chloroplast genome engineering remains largely undeveloped, with most
Alessandro Occhialini +6 more
wiley +1 more source
Two models (with and without outlier) for prediction of bicyclogermacrene concentrations from transcript levels of MEP and MVA pathway genes.
Robert Lanfear (395145) +4 more
core +1 more source

