Results 91 to 100 of about 26,893 (208)

KIF11 manipulates SREBP2‐dependent mevalonate cross talk to promote tumor progression in pancreatic ductal adenocarcinoma

Cancer Medicine, 2022
Cholesterol metabolism is highly correlated with risks of pancreatic ductal adenocarcinoma (PDAC). Nevertheless, the underlying mechanisms of activation of cholesterol biogenesis remain inconclusive.
Xiang Gu, Qunshan Zhu, Guangyu Tian, Wenbo Song, Tao Wang, Ali Wang, Xiaojun Chen, Songbing Qin   +7 more
doaj   +1 more source

Sedimentary membrane lipids recycled by deep-sea benthic archaea [PDF]

, 2010
http://www.godac.jamstec.go.jp/darwin/cruise/natsushima/nt06-04/ehttp://www.godac.jamstec.go.jp/darwin/cruise/natsushima/nt06-05/ehttp://www.godac.jamstec.go.jp/darwin/cruise/natsushima/nt06-22/ehttp://www.godac.jamstec.go.jp/darwin/cruise/natsushima ...
CHIKARAISHI, Yoshito, Hinrichs, Kai-Uwe, HINRICHS, Kai-Uwe, INAGAKI, Fumio, KITAZATO, Hiroshi, MORONO, Yuki, NOMAKI, Hidetaka, OGAWA, Nanako, OHKOUCHI, Naohiko, TAKANO, Yoshinori, 力石, 嘉人, 北里, 洋, 大河内, 直彦, 小川, 奈々子, 稲垣, 史生, 諸野, 祐樹, 野牧, 秀隆, 高野, 淑識   +17 more
core   +1 more source

Towards an integrated molecular understanding of plant hormones

Journal of Integrative Plant Biology, EarlyView.
This review offers a comprehensive overview of the nine plant hormones, delving into their biosynthesis, transport, signaling and crosstalk mechanisms. Because the complexity of plant hormonal control goes beyond these core elements, additional specific features are discussed. Lastly, this review highlights how fundamental insights drive hormonal‐based
Louise Vilain, Marie‐Laure Fauconnier, Manon Genva   +2 more
wiley   +1 more source

Mevalonate Diphosphate Decarboxylase MVD/Erg19 Is Required for Ergosterol Biosynthesis, Growth, Sporulation and Stress Tolerance in Aspergillus oryzae

Frontiers in Microbiology, 2019
Mevalonate diphosphate decarboxylase (MVD; EC 4.1.1.33) is a key enzyme of the mevalonic acid (MVA) pathway. In fungi, the MVA pathway functions as upstream of ergosterol biosynthesis, and MVD is also known as Erg19.
Yunlong Sun, Yali Niu, Hui Huang, Bin He, Long Ma, Yayi Tu, Van-Tuan Tran, Van-Tuan Tran, Bin Zeng, Zhihong Hu   +9 more
doaj   +1 more source

Combining Metabolomics and Transcriptomics to Characterize Tanshinone Biosynthesis in Salvia Miltiorrhiza [PDF]

, 2014
Plant natural products have been co-opted for millennia by humans for various uses such as flavor, fragrances, and medicines. These compounds often are only produced in relatively low amounts and are difficult to chemically synthesize, limiting access ...
Cui, Guanghong, Gao, Wei, Hillwig, Matthew L, Huang, Luqi, Jackson, Alana, Peters, Reuben J, Shen, Ye, Sun, Hai-Xi, Wang, Xiao, Wang, Xiu-Jie, Xiao, Hongbin, Zhang, Liangxiao, Zhao, Nan   +12 more
core   +3 more sources

The Role of the Hyoid Bone in Obstructive Sleep Apnea Severity: A Systematic Review

Journal of Sleep Research, EarlyView.
ABSTRACT Obstructive sleep apnea (OSA) has numerous complications that negatively impact patients' quality of life. Early diagnosis can significantly reduce these complications. The aim of the study was to evaluate the relationship between the hyoid bone position and the severity of apnea, and to determine if hyoid‐related cephalometric variables can ...
Carmen María Correa‐Morillo, Paola Cardil París, Marta Macarena Paz‐Cortés, Andrea Martín‐Vacas, Giovanni Giovannini   +4 more
wiley   +1 more source

Additional file 1 of Optimizing the downstream MVA pathway using a combination optimization strategy to increase lycopene yield in Escherichia coli

, 2022
Additional file 1: Table S1. Primers used in this study. Figure S1. Ten colonies were randomly picked and analyzed by colony PCR to determine ratio of successfully assembled pHM-library, pMM-library, and pLM-library. M marker.
Cheng, Tao, Wang, Lili, Sun, Chao, Xie, Congxia   +3 more
openaire   +1 more source

Tracing the biosynthetic origin of limonoids and their functional groups through stable isotope labeling and inhibition in neem tree (Azadirachta indica) cell suspension

BMC Plant Biology, 2018
Background Neem tree serves as a cornucopia for triterpenoids called limonoids that are of profound interest to humans due to their diverse biological activities.
Thiagarayaselvam Aarthy, Fayaj A. Mulani, Avinash Pandreka, Ashish Kumar, Sharvani S. Nandikol, Saikat Haldar, Hirekodathakallu V. Thulasiram   +6 more
doaj   +1 more source

Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome. [PDF]

PLoS Pathogens, 2009
Modified vaccinia virus Ankara (MVA) is an attenuated double-stranded DNA poxvirus currently developed as a vaccine vector against HIV/AIDS. Profiling of the innate immune responses induced by MVA is essential for the design of vaccine vectors and for ...
Julie Delaloye, Thierry Roger, Quynh-Giao Steiner-Tardivel, Didier Le Roy, Marlies Knaup Reymond, Shizuo Akira, Virginie Petrilli, Carmen E Gomez, Beatriz Perdiguero, Jürg Tschopp, Giuseppe Pantaleo, Mariano Esteban, Thierry Calandra   +12 more
doaj   +1 more source

Modeling of Dolichol Mass Spectra Isotopic Envelopes as a Tool to Monitor Isoprenoid Biosynthesis1 [PDF]

, 2017
The cooperation of the mevalonate (MVA) and methylerythritol phosphate (MEP) pathways, operating in parallel in plants to generate isoprenoid precursors, has been studied extensively. Elucidation of the isoprenoid metabolic pathways is indispensable for
Chojnacki, Tadeusz, Danikiewicz, Witold, Jóźwiak, Adam, Kania, Magdalena, Lipko, Agata, Poznański, Jarosław, Pączkowski, Cezary, Surmacz, Liliana, Swiezewska, Ewa, Witek, Agnieszka, Wójcik, Jacek, Zdanowski, Konrad   +11 more
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