Results 101 to 110 of about 17,684 (224)

Modulation of the Isoprenoid/Cholesterol Biosynthetic Pathway during Neuronal Differentiation in vitro [PDF]

, 2016
During differentiation, neurons acquire their typical shape and functional properties. At present, it is unclear, whether this important developmental step involves metabolic changes.
Ilenia Di Tunno, Segatto, M. (Marco), Marco Segatto, Pfrieger, Frank, Cartocci, V. (Veronica), Pallottini, V. (Valentina), SEGATTO, MARCO, Valentina Pallottini, Di Tunno, I. (Ilenia), Pfrieger, Frank W, PALLOTTINI, Valentina, Veronica Cartocci, Frank W. Pfrieger, CARTOCCI, VERONICA, Di Tunno, Ilenia, LEONE, STEFANO, Stefano Leone, Pfrieger, F. (Frank), Pfrieger, Frank W., Leone, S. (Stefano), Tunno, Ilenia Di   +20 more
core   +1 more source

Mevalonate Diphosphate Decarboxylase MVD/Erg19 Is Required for Ergosterol Biosynthesis, Growth, Sporulation and Stress Tolerance in Aspergillus oryzae

Frontiers in Microbiology, 2019
Mevalonate diphosphate decarboxylase (MVD; EC 4.1.1.33) is a key enzyme of the mevalonic acid (MVA) pathway. In fungi, the MVA pathway functions as upstream of ergosterol biosynthesis, and MVD is also known as Erg19.
Yunlong Sun, Yali Niu, Hui Huang, Bin He, Long Ma, Yayi Tu, Van-Tuan Tran, Van-Tuan Tran, Bin Zeng, Zhihong Hu   +9 more
doaj   +1 more source

Orchid genome evolution and trait innovation

Journal of Integrative Plant Biology, EarlyView.
Orchids became one of the world's most diverse plant groups through genome‐driven innovations, unique relationships with fungi and pollinators, and remarkable adaptability. This review explains the origins of orchids and the evolution of their distinctive life forms, flowers, and ecological strategies and highlights promising directions for future ...
Meng‐Yao Zeng, Cheng‐Yuan Zhou, Linying Wang, Jie Gao, Weilun Yin, Dong‐Hui Peng, Siren Lan, Feng‐Xi Yang, Zhong‐Jian Liu   +8 more
wiley   +1 more source

Mutant p53, the Mevalonate Pathway and the Tumor Microenvironment Regulate Tumor Response to Statin Therapy

, 2022
SIMPLE SUMMARY: For tumors to initiate and sustain rapid growth, they need to alter their metabolic reprograming to support this growth. While many oncogenes upregulate metabolic pathways in cancer, here, we focus on how mutant p53 interacts with the ...
Pereira, Madison, Glogova, Alice, Kathy Matuszewska, Jim Petrik, Matuszewska, Kathy, Madison Pereira, Petrik, Jim, Alice Glogova   +7 more
core   +1 more source

Tracing the biosynthetic origin of limonoids and their functional groups through stable isotope labeling and inhibition in neem tree (Azadirachta indica) cell suspension

BMC Plant Biology, 2018
Background Neem tree serves as a cornucopia for triterpenoids called limonoids that are of profound interest to humans due to their diverse biological activities.
Thiagarayaselvam Aarthy, Fayaj A. Mulani, Avinash Pandreka, Ashish Kumar, Sharvani S. Nandikol, Saikat Haldar, Hirekodathakallu V. Thulasiram   +6 more
doaj   +1 more source

The Role of the Hyoid Bone in Obstructive Sleep Apnea Severity: A Systematic Review

Journal of Sleep Research, EarlyView.
ABSTRACT Obstructive sleep apnea (OSA) has numerous complications that negatively impact patients' quality of life. Early diagnosis can significantly reduce these complications. The aim of the study was to evaluate the relationship between the hyoid bone position and the severity of apnea, and to determine if hyoid‐related cephalometric variables can ...
Carmen María Correa‐Morillo, Paola Cardil París, Marta Macarena Paz‐Cortés, Andrea Martín‐Vacas, Giovanni Giovannini   +4 more
wiley   +1 more source

Additional file 1: of A novel MVA-mediated pathway for isoprene production in engineered E. coli

, 2016
Optimization of Fermentation Process and three Figs. (DOCX 216 kb)
Yang, Jianming, Nie, Qingjuan, Liu, Hui, Xian, Mo, Liu, Huizhou   +4 more
openaire   +1 more source

Gene Editing of Nicotiana benthamiana Architecture for Space‐Efficient Production of Recombinant Proteins in Closed Environments

Plant Biotechnology Journal, EarlyView.
ABSTRACT Indoor vertical farming (VF) offers practical advantages for the cultivation of plant protein bio‐factories including plant uniformity, product consistency, water/nutrient recycling and production cycles on a year‐round basis. Much progress has been achieved toward the development of innovative systems for artificial lighting, automated ...
Béatrice Giroux, Kristina LeBreux, Louis Feyzeau, Marie‐Claire Goulet, Charles Goulet, Dominique Michaud   +5 more
wiley   +1 more source

Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families

Plant, Cell &Environment, EarlyView.
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor, Kavita Verma, Nishu, Barkat Hussain, Vartika Mathur   +4 more
wiley   +1 more source

Elevated desmoglein‐2 expression in multiple myeloma is a prognostic marker across genomic subtypes with impact on high‐risk cytogenetics and a distinct gene expression profile

British Journal of Haematology, EarlyView.
Barbara J. McClure, John Toubia, Charlotte E. J. Toomes, O. Giles Best, Angelina Yong, Cindy H. Lee, Claudine S. Bonder, Chung Hoow Kok   +7 more
wiley   +1 more source