Results 101 to 110 of about 333,256 (300)

The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability [PDF]

, 2009
Myc-induced SUN domain–containing protein (Misu or NSun2) is a nucleolar RNA methyltransferase important for c-Myc–induced proliferation in skin, but the mechanisms by which Misu contributes to cell cycle progression are unknown.
Michaela Frye, Benavente, Sandra Blanco, Elisabete Nascimento, Kurowski, Agata, Nascimento, Elisabete, Hussain, Shobbir, Ilaria Dragoni, Dragoni, Ilaria, Gillich, Astrid, Shobbir Hussain, Sandra Blanco Benavente, Astrid Gillich, Frye, Michaela, Peter Humphreys, Humphreys, Peter, Agata Kurowski   +15 more
core   +1 more source

Cazarin and Derollo et al Figure 3 and Supplemental Figure 3: SHEP N-MYC-ER Phase Set Enrichment Analysis (PSEA) ResultsSource data for MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesis

, 2023
Source data from Phase Set Enrichment Analysis (PSEA) of oscillating genes from SHEP N-MYC-ER OFF and ON.
Brian J. Altman (16819407), Aalim M. Weljie (244968), Chi V. Dang (9424989), Brian Altman (14202566), Stephano S. Mello (15101894), Rebekah Brooks (16819404), Siti Noor Ain Binti Ahmad Shahidan (16819392), Zandra E. Walton (16819401), Jamison B. Burchett (9707399), Daniel Mwangi (16819395), Rachel E. DeRollo (16819389), Annie L. Hsieh (16819398), Saikumari Krishnaiah (4433761), Juliana Cazarin (16819386), Brian Altman (17117536)   +14 more
core   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Deciphering the role of MYC Gene Variants in Childhood Cerebral Adrenoleukodystrophy (ccALD) using Integrative Transcriptomic and Variant Analysis [PDF]

BIO Web of Conferences
Objective: Childhood cerebral adrenoleukodystrophy (ccALD) is a severe neurodegenerative disorder characterized by rapid demyelination and disruption of the blood-brain barrier (BBB).
Jain Chakresh Kumar, Maurya Sarita, Tripathi Pankaj Kumar, Mishra Divya   +3 more
doaj   +1 more source

c-Myc induced changes in higher order rDNA structure accompany growth factor stimulation of quiescent cells

, 2007
Human c-Myc is believed to be a high level coordinator of protein synthesis capacity and cell growth rate, capable of activating transcription by all three nuclear RNA Polymerases.
Rachel G. Berkson, Chiou-Nan Shiue, Anthony P. H. Wright   +2 more
core  

C-myc and immunoglobulin kappa light chain constant genes are on the 8q+ chromosome of three Burkitt lymphoma lines with t(2;8) translocations [PDF]

, 1984
We have determined the localization of c-myc and the immunoglobulin kappa light chain genes on the 8q+/2p- chromosomes of the three Burkitt lymphoma lines BL21, LY66 and LY91 with t(2;8) translocation by in situ hybridization.
Cremer, Thomas, Lenoire, Gilbert M., Rappold, Gudrun A., Bornkamm, Georg W., Adolph, Sabine, Hameister, Horst, Henglein, Berthold, Freese, Ulrich-K.   +7 more
core  

Brief inactivation of c-Myc is not sufficient for sustained regression of c-Myc-induced tumours of pancreatic islets and skin epidermis-2

, 2011
Copyright information:Taken from "Brief inactivation of c-Myc is not sufficient for sustained regression of c-Myc-induced tumours of pancreatic islets and skin epidermis"BMC Biology 2004;2():26-26.Published online 21 Dec 2004PMCID:PMC544575.Copyright ...
Sevasti Zervou (71022), Stella Pelengaris (71018), Linda Cheung (71020), Michael Khan (71023), Sylvie Abouna (71019), Vasiliki Ifandi (71021)   +5 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

The predictive value of immunohistochemistry for MYC, BCL2, and BCL6 in fluorescence in situ hybridization in aggressive mature B-cell lymphomas and re-evaluation according to the 5th edition of the World Health Organization classification: A single-center 9-year experience

Indian Journal of Pathology and Microbiology
Background: Diffuse large B-cell lymphoma/High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 translocations (DLBCL/HGBL-MYC/BCL2) represent a distinct and rare diagnostic category in 5th Edition World Health Organization (WHO-HAEM5) classification.
Nuray Bassullu, Fatma Tokat, Irem Guvendir, Cansu Gokpinar, Tulay Tecimer   +4 more
doaj   +1 more source

Brief inactivation of c-Myc is not sufficient for sustained regression of c-Myc-induced tumours of pancreatic islets and skin epidermis-3

, 2011
Copyright information:Taken from "Brief inactivation of c-Myc is not sufficient for sustained regression of c-Myc-induced tumours of pancreatic islets and skin epidermis"BMC Biology 2004;2():26-26.Published online 21 Dec 2004PMCID:PMC544575.Copyright ...
Sevasti Zervou (71022), Stella Pelengaris (71018), Linda Cheung (71020), Michael Khan (71023), Sylvie Abouna (71019), Vasiliki Ifandi (71021)   +5 more
core   +1 more source